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Biology and Biochemistry

D-Index
61
Citations
18230
World Ranking
11161
National Ranking
404

Overview

Frédéric Relaix is affiliated with Paris-Est Créteil University in France. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a notable focus on Medicine. Within these domains, key subfields include Molecular Biology, Genetics, Physiology, Cardiology and Cardiovascular Medicine, and Surgery.

Their main research topics revolve around Muscle Physiology and Disorders, Pluripotent Stem Cells Research, Tissue Engineering and Regenerative Medicine, Adipose Tissue and Metabolism, RNA Research and Splicing, Neurogenetic and Muscular Disorders Research, and Mesenchymal Stem Cell Research.

Frédéric Relaix has published extensively, with frequent contributions to the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neuromuscular Disorders
  • Nature Communications
  • Skeletal Muscle
  • Stem Cell Reports

Representative recent publications include:

  • Perspectives on skeletal muscle stem cells, 2021, Nature Communications
  • Platelets Facilitate the Wound-Healing Capability of Mesenchymal Stem Cells by Mitochondrial Transfer and Metabolic Reprogramming, 2021, Cell Metabolism
  • Single-nucleus RNA-seq and FISH identify coordinated transcriptional activity in mammalian myofibers, 2020, Nature Communications
  • Tissue damage induces a conserved stress response that initiates quiescent muscle stem cell activation, 2021, Cell stem cell
  • Direct contribution of skeletal muscle mesenchymal progenitors to bone repair, 2021, Nature Communications

Throughout their research career, Frédéric Relaix has collaborated frequently with several co-authors, including Marianne Gervais, François-Jérôme Authier, Baptiste Periou, Valentina Taglietti, and Laurent Tiret.

Best Publications

  • A Pax3/Pax7-dependent population of skeletal muscle progenitor cells

    Frédéric Relaix;Didier Rocancourt;Ahmed Mansouri;Margaret Buckingham

  • Direct isolation of satellite cells for skeletal muscle regeneration.

    Didier Montarras;Jennifer Morgan;Charlotte Collins;Frédéric Relaix

  • The formation of skeletal muscle: from somite to limb.

    Margaret Buckingham;Lola Bajard;Ted Chang;Philippe Daubas

  • Satellite cells are essential for skeletal muscle regeneration: the cell on the edge returns centre stage.

    Frederic Relaix;Frederic Relaix;Peter S. Zammit

  • Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells

    Frédéric Relaix;Didier Montarras;Stéphane Zaffran;Barbara Gayraud-Morel

  • Pax7 and myogenic progression in skeletal muscle satellite cells.

    Peter S. Zammit;Frederic Relaix;Yosuke Nagata;Ana Pérez Ruiz

  • The role of Pax genes in the development of tissues and organs: Pax3 and Pax7 regulate muscle progenitor cell functions.

    Margaret Buckingham;Frédéric Relaix

  • Differentiation of pluripotent stem cells to muscle fiber to model Duchenne muscular dystrophy.

    Jérome Chal;Masayuki Oginuma;Ziad Al Tanoury;Bénédicte Gobert

  • Divergent functions of murine Pax3 and Pax7 in limb muscle development

    Frédéric Relaix;Didier Rocancourt;Ahmed Mansouri;Margaret Buckingham

  • A novel genetic hierarchy functions during hypaxial myogenesis: Pax3 directly activates Myf5 in muscle progenitor cells in the limb

    Lola Bajard;Frédéric Relaix;Mounia Lagha;Didier Rocancourt

  • Muscle contraction is necessary to maintain joint progenitor cell fate.

    Joy Kahn;Yulia Shwartz;Einat Blitz;Sharon Krief

  • In Situ Fixation Redefines Quiescence and Early Activation of Skeletal Muscle Stem Cells

    Léo Machado;Joana Esteves de Lima;Odile Fabre;Caroline Proux

  • Perspectives on skeletal muscle stem cells

    F. Relaix;M. Bencze;M. J. Borok;A. Der Vartanian

  • Reciprocal signalling by Notch-Collagen V-CALCR retains muscle stem cells in their niche.

    Meryem B. Baghdadi;Meryem B. Baghdadi;David Castel;Léo Machado;So-ichiro Fukada

  • PAX3 and PAX7 as upstream regulators of myogenesis.

    Margaret Buckingham;Frédéric Relaix

  • Muscle hypertrophy driven by myostatin blockade does not require stem/precursor-cell activity

    Helge Amthor;Anthony Otto;Adeline Vulin;Anne Rochat

  • Pw1/Peg3 is a potential cell death mediator and cooperates with Siah1a in p53-mediated apoptosis

    Frédéric Relaix;Xiao Jun Wei;Wei Li;Jianjing Pan

  • Smooth muscle of the dorsal aorta shares a common clonal origin with skeletal muscle of the myotome.

    Milan Esner;Sigolène M. Meilhac;Frédéric Relaix;Jean-François Nicolas

  • Peg3/Pw1 is an imprinted gene involved in the TNF-NFκB signal transduction pathway

    Frédéric Relaix;Xiao-Jun Wei;Xiangwei Wu;David A. Sassoon

  • Single-nucleus RNA-seq and FISH identify coordinated transcriptional activity in mammalian myofibers.

    Matthieu Dos Santos;Stéphanie Backer;Benjamin Saintpierre;Brigitte Izac

Frequent Co-Authors

Margaret Buckingham
Margaret Buckingham Institut Pasteur
Shahragim Tajbakhsh
Shahragim Tajbakhsh Institut Pasteur
Peter S. Zammit
Peter S. Zammit King's College London
Ana Cumano
Ana Cumano Institut Pasteur
Delphine Duprez
Delphine Duprez Université Paris Cité
David Sassoon
David Sassoon Université Paris Cité
Ahmed Mansouri
Ahmed Mansouri Max Planck Society
Romain K. Gherardi
Romain K. Gherardi Paris-Est Créteil University
Jennifer E. Morgan
Jennifer E. Morgan University College London

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