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Molecular Biology

D-Index
64
Citations
12392
World Ranking
1761
National Ranking
141

Overview

Jennifer E. Morgan is affiliated with University College London in the United Kingdom. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant contributions in medicine. Morgan's work centers on several subfields, including molecular biology, genetics, surgery, physiology, and rehabilitation.

The scientist's research topics cover a range of areas related to muscle physiology and disorders, tissue engineering and regenerative medicine, CRISPR and genetic engineering, virus-based gene therapy research, exercise and physiological responses, adipose tissue and metabolism, as well as neurogenetic and muscular disorders research.

Morgan's recent published papers include:

  • Increased dystrophin production with golodirsen in patients with Duchenne muscular dystrophy (2020, Neurology)
  • Long-Term Safety and Efficacy Data of Golodirsen in Ambulatory Patients with Duchenne Muscular Dystrophy Amenable to Exon 53 Skipping: A First-in-human, Multicenter, Two-Part, Open-Label, Phase 1/2 Trial (2021, Nucleic Acid Therapeutics)
  • Skeletal muscle in health and disease (2020, Disease Models & Mechanisms)
  • Myostatin inhibition in combination with antisense oligonucleotide therapy improves outcomes in spinal muscular atrophy (2020, Journal of Cachexia Sarcopenia and Muscle)
  • The administration of antisense oligonucleotide golodirsen reduces pathological regeneration in patients with Duchenne muscular dystrophy (2021, Acta Neuropathologica Communications)

Frequent co-authors collaborating with Morgan include:

  • Francesco Muntoni (13 publications)
  • Jinhong Meng (10 publications)
  • Silvia Torelli (8 publications)
  • Volker Straub (6 publications)
  • Francesco Catapano (6 publications)

Morgan has published extensively in several scientific journals. The most frequent publication venues are:

  • Neuromuscular Disorders (4 publications)
  • Acta Neuropathologica Communications (3 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (3 publications)
  • Molecular Therapy - Methods & Clinical Development (2 publications)
  • Cells (2 publications)

Best Publications

  • Direct isolation of satellite cells for skeletal muscle regeneration.

    Didier Montarras;Jennifer Morgan;Charlotte Collins;Frédéric Relaix

  • Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study.

    Sebahattin Cirak;Virginia Arechavala-Gomeza;Michela Guglieri;Lucy Feng

  • Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: a single-blind, placebo-controlled, dose-escalation, proof-of-concept study

    Maria Kinali;Maria Kinali;Virginia Arechavala-Gomeza;Lucy Feng;Sebahattin Cirak

  • Antisense-induced exon skipping and synthesis of dystrophin in the mdx mouse

    Christopher J. Mann;Kaite Honeyman;Andy J. Cheng;Tina Ly

  • Increased dystrophin production with golodirsen in patients with Duchenne muscular dystrophy.

    Diane E. Frank;Frederick J. Schnell;Cody Akana;Saleh H. El-Husayni

  • Comparative analysis of antisense oligonucleotide sequences for targeted skipping of exon 51 during dystrophin pre-mRNA splicing in human muscle

    V. Arechavala-Gomeza;I.R. Graham;L.J. Popplewell;Abbie Adams

  • BMP signalling permits population expansion by preventing premature myogenic differentiation in muscle satellite cells

    Yusuke Ono;Frederico Calhabeu;Jennifer Elizabeth Morgan;Takenobu Katagiri

  • Muscle satellite cells are a functionally heterogeneous population in both somite-derived and branchiomeric muscles

    Yusuke Ono;Luisa Boldrin;Paul Knopp;Jennifer E. Morgan

  • Age-related changes in replication of myogenic cells in mdx mice: quantitative autoradiographic studies

    John K. McGeachie;Miranda D. Grounds;Terence A. Partridge;Jennifer E. Morgan

  • Are Human and Mouse Satellite Cells Really the Same

    L Boldrin;F Muntoni;JE Morgan

  • Galectin-1 Induces Skeletal Muscle Differentiation in Human Fetal Mesenchymal Stem Cells and Increases Muscle Regeneration

    Jerry Chan;Keelin O'Donoghue;Manuela Gavina;Yvan Torrente

  • Integrated functions of Pax3 and Pax7 in the regulation of proliferation, cell size and myogenic differentiation.

    Charlotte A. Collins;Viola F. Gnocchi;Robert B. White;Luisa Boldrin

  • Dystrophin quantification and clinical correlations in Becker muscular dystrophy: implications for clinical trials

    Karen Anthony;Sebahattin Cirak;Silvia Torelli;Giorgio Tasca

  • Widespread Distribution and Muscle Differentiation of Human Fetal Mesenchymal Stem Cells After Intrauterine Transplantation in Dystrophic mdx Mouse

    Jerry Chan;Simon N. Waddington;Keelin O'Donoghue;Hitoshi Kurata

  • Restoration of the Dystrophin-associated Glycoprotein Complex After Exon Skipping Therapy in Duchenne Muscular Dystrophy

    Sebahattin Cirak;Lucy Feng;Karen Anthony;Virginia Arechavala-Gomeza

  • A Novel Morpholino Oligomer Targeting ISS-N1 Improves Rescue of Severe Spinal Muscular Atrophy Transgenic Mice

    Haiyan Zhou;Narinder Janghra;Chalermchai Mitrpant;Rachel L. Dickinson

  • Dystrophin quantification: Biological and translational research implications

    Karen Anthony;Virginia Arechavala-Gomeza;Laura E. Taylor;Adeline Vulin

  • Loss-of-function mutations in SCN4A cause severe foetal hypokinesia or ‘classical’ congenital myopathy

    Irina T. Zaharieva;Michael G. Thor;Emily C. Oates;Emily C. Oates;Clara Van Karnebeek

  • Direct effects of the pathogenic mutation on satellite cell function in muscular dystrophy.

    Jennifer E. Morgan;Peter S. Zammit

  • Recent progress in satellite cell/myoblast engraftment -- relevance for therapy.

    Unknown

Frequent Co-Authors

Francesco Muntoni
Francesco Muntoni University College London
Volker Straub
Volker Straub Newcastle University
Caroline Sewry
Caroline Sewry University College London
Peter S. Zammit
Peter S. Zammit King's College London
Kate Bushby
Kate Bushby Newcastle University
George Dickson
George Dickson Royal Holloway University of London
Matthew J.A. Wood
Matthew J.A. Wood University of Oxford
Dominic J. Wells
Dominic J. Wells Royal Veterinary College
Terence A. Partridge
Terence A. Partridge Children’s National Health System
Alessandra Ferlini
Alessandra Ferlini University of Ferrara

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