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Biology and Biochemistry
UK
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
101
Citations
55385
World Ranking
1414
National Ranking
83

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United Kingdom Leader Award

Overview

Matthew J.A. Wood is affiliated with the University of Oxford in the United Kingdom. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a notable focus on Medicine. Within these areas, the scientist's work is concentrated in several subfields, including Molecular Biology, Genetics, Cellular and Molecular Neuroscience, Cancer Research, and Immunology.

The major topics explored in their research include RNA Interference and Gene Delivery, Muscle Physiology and Disorders, Extracellular vesicles in disease, Neurogenetic and Muscular Disorders Research, Advanced biosensing and bioanalysis techniques, RNA Research and Splicing, and RNA modifications and cancer.

Selected recent publications demonstrate the scope of their work:

  • "Advances in oligonucleotide drug delivery," 2020, Nature Reviews Drug Discovery
  • "Extracellular vesicles as a next-generation drug delivery platform," 2021, Nature Nanotechnology
  • "A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA," 2020, Nature Communications
  • "Exosomes mediate sensory hair cell protection in the inner ear," 2020, Journal of Clinical Investigation
  • "Therapeutic approaches for Duchenne muscular dystrophy," 2023, Nature Reviews Drug Discovery

Frequent co-authors include Thomas C. Roberts, Samir EL Andaloussi, Imre Mäger, Dhanu Gupta, and Mariana Conceição. Their collaborations suggest ongoing work in similar areas of molecular and genetic research.

Major venues for publication reveal a pattern of dissemination primarily in high-impact and specialized journals. These venues include bioRxiv (Cold Spring Harbor Laboratory), Molecular Therapy - Nucleic Acids, Nature Communications, Nucleic Acids Research, and Molecular Therapy.

In addition to journal publications, Matthew J.A. Wood has contributed to book literature, with a title published by Hart Publishing eBooks titled Not What The Bus Promised in 2023.

Best Publications

  • Genome-wide atlas of gene expression in the adult mouse brain

    Ed S. Lein;Michael J. Hawrylycz;Nancy Ao;Mikael Ayres

  • Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

    Lydia Alvarez-Erviti;Yiqi Seow;HaiFang Yin;Corinne Betts

  • Extracellular vesicles: biology and emerging therapeutic opportunities

    Samir El Andaloussi;Imre Mäger;Imre Mäger;Xandra O. Breakefield;Matthew J. A. Wood

  • Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting

    Oscar P. B. Wiklander;Joel Z. Nordin;Aisling O'Loughlin;Ylva Gustafsson

  • Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study.

    Sebahattin Cirak;Virginia Arechavala-Gomeza;Michela Guglieri;Lucy Feng

  • Extracellular vesicles as a next-generation drug delivery platform.

    Inge Katrin Herrmann;Inge Katrin Herrmann;Matthew John Andrew Wood;Gregor Fuhrmann;Gregor Fuhrmann

  • Exosomes and microvesicles: extracellular vesicles for genetic information transfer and gene therapy

    Yi Lee;Samir El Andaloussi;Samir El Andaloussi;Matthew J.A. Wood

  • Extracellular Vesicle Heterogeneity: Subpopulations, Isolation Techniques, and Diverse Functions in Cancer Progression

    Eduard Willms;Carlos Cabañas;Carlos Cabañas;Imre Mäger;Imre Mäger;Matthew J.A. Wood

  • Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: a single-blind, placebo-controlled, dose-escalation, proof-of-concept study

    Maria Kinali;Maria Kinali;Virginia Arechavala-Gomeza;Lucy Feng;Sebahattin Cirak

  • Cells release subpopulations of exosomes with distinct molecular and biological properties

    Eduard Willms;Henrik J. Johansson;Imre Mäger;Imre Mäger;Yi Lee

  • Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission

    L Alvarez-Erviti;Y Seow;A H Schapira;C Gardiner

  • Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties

    Joel Z. Nordin;Yi Lee;Pieter Vader;Imre Mäger;Imre Mäger

  • Electroporation-induced siRNA precipitation obscures the efficiency of siRNA loading into extracellular vesicles.

    Sander A.A. Kooijmans;Stephan Stremersch;Kevin Braeckmans;Stefaan C. de Smedt

  • Isolation of Exosomes from Blood Plasma: Qualitative and Quantitative Comparison of Ultracentrifugation and Size Exclusion Chromatography Methods.

    Tamás Baranyai;Kata Herczeg;Zsófia Onódi;István Voszka

  • DNA Cage Delivery to Mammalian Cells

    Anthony S. Walsh;HaiFang Yin;Christoph M. Erben;Matthew J. A. Wood

  • Exosome-mediated delivery of siRNA in vitro and in vivo

    Samir El-Andaloussi;Samir El-Andaloussi;Yi Lee;Samira Lakhal-Littleton;Jinghuan Li

  • Extracellular vesicle-based therapeutics: natural versus engineered targeting and trafficking.

    Daniel E. Murphy;Olivier G. de Jong;Maarten Brouwer;Matthew J. Wood

  • Exosomes for targeted siRNA delivery across biological barriers.

    Samir El Andaloussi;Samira Lakhal;Imre Mäger;Matthew J.A. Wood

  • Systemic exosomal siRNA delivery reduced alpha-synuclein aggregates in brains of transgenic mice.

    JM Cooper;PB Wiklander;JZ Nordin;R Al-Shawi

  • Extracellular vesicles: emerging targets for cancer therapy.

    Pieter Vader;Xandra O. Breakefield;Matthew J.A. Wood

Frequent Co-Authors

Samir El Andaloussi
Samir El Andaloussi Karolinska Institute
Lucy Fortson
Lucy Fortson University of Minnesota
R. A. Ong
R. A. Ong University of California, Los Angeles
J. P. Finley
J. P. Finley Purdue University West Lafayette
Michael J. Gait
Michael J. Gait MRC Laboratory of Molecular Biology
S. P. Wakely
S. P. Wakely University of Chicago
Wystan Benbow
Wystan Benbow Harvard University
John L. Quinn
John L. Quinn University College Cork
T. C. Weekes
T. C. Weekes Harvard University
F. Krennrich
F. Krennrich Iowa State University

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