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Genetics

D-Index
67
Citations
20857
World Ranking
2510
National Ranking
94

Overview

Annemieke Aartsma-Rus is affiliated with Leiden University Medical Center in the Netherlands. Their research primarily focuses on areas within Biochemistry, Genetics, and Molecular Biology as well as Medicine.

The scientist has contributed to multiple fields of study, including:

  • Molecular Biology
  • Genetics
  • Physiology
  • Cardiology and Cardiovascular Medicine
  • Biomedical Engineering

The main topics covered in their work include:

  • Muscle Physiology and Disorders
  • Neurogenetic and Muscular Disorders Research
  • RNA Research and Splicing
  • CRISPR and Genetic Engineering
  • RNA Interference and Gene Delivery
  • Adipose Tissue and Metabolism
  • Cardiomyopathy and Myosin Studies

Frequent coauthors in their publications are:

  • Maaike van Putten (29 publications)
  • Pietro Spitali (19 publications)
  • David van de Vijver (15 publications)
  • E. Niks (13 publications)
  • Marlen C. Lauffer (12 publications)

They have published extensively across several journals and venues, including:

  • Neuromuscular Disorders (28 publications)
  • Nucleic Acid Therapeutics (12 publications)
  • Journal of Neuromuscular Diseases (9 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (8 publications)
  • PLoS ONE (4 publications)

Some recent papers authored by Annemieke Aartsma-Rus include:

  • "Duchenne muscular dystrophy," 2021, Nature Reviews Disease Primers
  • "Delivery of oligonucleotide-based therapeutics: challenges and opportunities," 2021, EMBO Molecular Medicine
  • "Possibilities and limitations of antisense oligonucleotide therapies for the treatment of monogenic disorders," 2024, Communications Medicine
  • "Opportunities and challenges for antisense oligonucleotide therapies," 2020, Journal of Inherited Metabolic Disease
  • "The 10th Oligonucleotide Therapy Approved: Golodirsen for Duchenne Muscular Dystrophy," 2020, Nucleic Acid Therapeutics

Best Publications

  • Local Dystrophin Restoration with Antisense Oligonucleotide PRO051

    Judith C. van Deutekom;Anneke A. Janson;Ieke B. Ginjaar;Wendy S. Frankhuizen

  • Systemic administration of PRO051 in Duchenne's muscular dystrophy.

    Nathalie M Goemans;Mar Tulinius;Johanna T van den Akker;Brigitte E Burm

  • Entries in the Leiden Duchenne muscular dystrophy mutation database: an overview of mutation types and paradoxical cases that confirm the reading-frame rule.

    Annemieke Aartsma-Rus;Judith C. T. Van Deutekom;Ivo F. Fokkema;Gert-Jan B. Van Ommen

  • Duchenne muscular dystrophy.

    Dongsheng Duan;Nathalie Goemans;Shin'ichi Takeda;Eugenio Mercuri

  • Theoretic applicability of antisense-mediated exon skipping for Duchenne muscular dystrophy mutations.

    Annemieke Aartsma-Rus;Ivo Fokkema;Jan Verschuuren;Ieke Ginjaar

  • The TREAT-NMD DMD Global Database: Analysis of More than 7,000 Duchenne Muscular Dystrophy Mutations

    Catherine L. Bladen;David Salgado;Soledad Monges;Maria E. Foncuberta

  • Digenic inheritance of an SMCHD1 mutation and an FSHD-permissive D4Z4 allele causes facioscapulohumeral muscular dystrophy type 2

    Richard J.L.F. Lemmers;Rabi Tawil;Lisa M. Petek;Judit Balog

  • Prevalence, incidence and carrier frequency of 5q–linked spinal muscular atrophy – a literature review

    Ingrid E. C. Verhaart;Agata Robertson;Ian J. Wilson;Annemieke Aartsma-Rus

  • Therapeutic antisense-induced exon skipping in cultured muscle cells from six different DMD patients

    Annemieke Aartsma-Rus;Anneke A.M. Janson;Wendy E. Kaman;Mattie Bremmer-Bout

  • Therapeutic developments for Duchenne muscular dystrophy.

    Ingrid E C Verhaart;Annemieke Aartsma-Rus

  • The importance of genetic diagnosis for Duchenne muscular dystrophy

    Annemieke Aartsma-Rus;Ieke B Ginjaar;Kate Bushby

  • Antisense-Induced Multiexon Skipping for Duchenne Muscular Dystrophy Makes More Sense

    Annemieke Aartsma-Rus;Anneke A.M. Janson;Wendy E. Kaman;Mattie Bremmer-Bout

  • FDA Approves Eteplirsen for Duchenne Muscular Dystrophy: The Next Chapter in the Eteplirsen Saga.

    Annemieke Aartsma-Rus;Arthur M. Krieg

  • Antisense-mediated exon skipping: A versatile tool with therapeutic and research applications

    Annemieke Aartsma-Rus;Gert-Jan B. van Ommen

  • Delivery of oligonucleotide-based therapeutics: challenges and opportunities.

    Suzan M. Hammond;Annemieke Aartsma-Rus;Sandra Alves;Sven Even F. Borgos

  • Targeted exon skipping as a potential gene correction therapy for Duchenne muscular dystrophy.

    Annemieke Aartsma-Rus;Mattie Bremmer-Bout;Anneke A.M Janson;Johan T den Dunnen

  • The Pathogenesis and Therapy of Muscular Dystrophies

    Simon Guiraud;Annemieke Aartsma-Rus;Natassia M. Vieira;Kay E. Davies

  • In vivo comparison of 2'-O-methyl phosphorothioate and morpholino antisense oligonucleotides for Duchenne muscular dystrophy exon skipping.

    Hans A. Heemskerk;Christa L. de Winter;Sjef J. de Kimpe;Petra van Kuik-Romeijn

  • Comparative analysis of antisense oligonucleotide sequences for targeted skipping of exon 51 during dystrophin pre-mRNA splicing in human muscle

    V. Arechavala-Gomeza;I.R. Graham;L.J. Popplewell;Abbie Adams

  • Current status of pharmaceutical and genetic therapeutic approaches to treat DMD.

    Christophe Pichavant;Annemieke Aartsma-Rus;Paula R Clemens;Kay E Davies

Frequent Co-Authors

Gert-Jan B. van Ommen
Gert-Jan B. van Ommen Leiden University Medical Center
Peter A. C. 't Hoen
Peter A. C. 't Hoen Radboud University
Francesco Muntoni
Francesco Muntoni University College London
Johan T. den Dunnen
Johan T. den Dunnen Leiden University Medical Center
Hanns Lochmüller
Hanns Lochmüller University of Freiburg
Jan J.G.M. Verschuuren
Jan J.G.M. Verschuuren Leiden University Medical Center
Volker Straub
Volker Straub Newcastle University
Alessandra Ferlini
Alessandra Ferlini University of Ferrara
Kate Bushby
Kate Bushby Newcastle University
Eugenio Mercuri
Eugenio Mercuri Catholic University of the Sacred Heart

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