D-Index & Metrics Best Publications
Johannes V. Swinnen

Johannes V. Swinnen

Biology and Biochemistry
Belgium
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 68 Citations 16,108 165 World Ranking 4947 National Ranking 85

Research.com Recognitions

Awards & Achievements

2023 - Research.com Biology and Biochemistry in Belgium Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Cancer

Johannes V. Swinnen mainly investigates Biochemistry, Fatty acid synthase, LNCaP, Cancer cell and Cancer research. His Fatty acid synthase study incorporates themes from Carcinogenesis, Sterol Regulatory Element Binding Protein 1, Sterol regulatory element-binding protein and Prostate. As part of the same scientific family, Johannes V. Swinnen usually focuses on LNCaP, concentrating on Cell growth and intersecting with Programmed cell death.

The Cancer cell study combines topics in areas such as Lipogenesis, Lyase, Enzyme, Cell biology and Membrane lipids. His work carried out in the field of Cancer research brings together such families of science as Apoptosis, Fas receptor and Fas ligand. His Prostate cancer study integrates concerns from other disciplines, such as Testosterone, Androgen and Dihydrotestosterone.

His most cited work include:

  • A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis. (611 citations)
  • Increased lipogenesis in cancer cells: new players, novel targets (443 citations)
  • EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research (431 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Internal medicine, Cancer research, Endocrinology, Cell biology and Androgen receptor. Johannes V. Swinnen has included themes like Cell culture and Oncology in his Internal medicine study. Johannes V. Swinnen interconnects Cancer, Prostate cancer, Fatty acid synthase and Programmed cell death in the investigation of issues within Cancer research.

His Cell biology research integrates issues from Cancer cell and Cell, Cell type. Johannes V. Swinnen has researched Cancer cell in several fields, including Lipogenesis, Biochemistry, Cell growth, Lipid metabolism and CD36. His Androgen receptor research includes elements of Molecular biology, Receptor, Glucocorticoid receptor and Sertoli cell.

He most often published in these fields:

  • Internal medicine (31.55%)
  • Cancer research (30.36%)
  • Endocrinology (28.57%)

What were the highlights of his more recent work (between 2017-2021)?

  • Cancer research (30.36%)
  • Cell biology (25.00%)
  • Prostate cancer (17.86%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Cancer research, Cell biology, Prostate cancer, Lipid metabolism and Cancer cell. His studies in Cancer research integrate themes in fields like Androgen, Prostate, Metastasis and Bortezomib. His Cell biology research is multidisciplinary, incorporating elements of Lipogenesis, Endocytosis and Oxidative phosphorylation.

Johannes V. Swinnen does research in Prostate cancer, focusing on Androgen receptor specifically. His research on Lipid metabolism also deals with topics like

  • Cancer which connect with Membrane lipids, Cell culture and Receptor,
  • Phospholipid that intertwine with fields like Biodistribution, LNCaP and Pharmacology. Cancer cell is often connected to Lipidomics in his work.

Between 2017 and 2021, his most popular works were:

  • Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity (118 citations)
  • Lipid metabolism in cancer cells under metabolic stress. (60 citations)
  • Impairment of angiogenesis by fatty acid synthase inhibition involves mTOR malonylation (59 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Cancer

Johannes V. Swinnen mainly focuses on Cell biology, Lipid metabolism, Cancer cell, Cancer research and Downregulation and upregulation. His Cell biology research integrates issues from Lipogenesis and Endocytosis. His Lipogenesis study incorporates themes from Sterol regulatory element-binding protein, Kinase activity, Malonyl-CoA, Targeted therapy and Fatty acid synthesis.

He interconnects Membrane biogenesis, Metabolic adaptation and Fatty acid in the investigation of issues within Cancer cell. The Cancer research study combines topics in areas such as Ceramide, Sphingomyelin, Acid sphingomyelinase and Multiple myeloma, Bortezomib. His Cancer study combines topics from a wide range of disciplines, such as Cell culture, Biochemistry, Cell growth, Biosynthesis and Membrane lipids.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis.

Karel De Gendt;Johannes V. Swinnen;Philippa T. K. Saunders;Luc Schoonjans.
Proceedings of the National Academy of Sciences of the United States of America (2004)

845 Citations

Increased lipogenesis in cancer cells: new players, novel targets

Johannes V Swinnen;Koen Brusselmans;Guido Verhoeven.
Current Opinion in Clinical Nutrition and Metabolic Care (2006)

727 Citations

EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research

Jan Van Deun;Pieter Mestdagh;Patrizia Agostinis;Özden Akay.
Nature Methods (2017)

660 Citations

De novo Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation

Evelien Rysman;Koen Brusselmans;Katryn Scheys;Leen Timmermans.
Cancer Research (2010)

580 Citations

Induction of Cancer Cell Apoptosis by Flavonoids Is Associated with Their Ability to Inhibit Fatty Acid Synthase Activity

Koen Brusselmans;Ruth Vrolix;Guido Verhoeven;Johannes V. Swinnen.
Journal of Biological Chemistry (2005)

533 Citations

Overexpression of fatty acid synthase is an early and common event in the development of prostate cancer

Johannes V. Swinnen;Tania Roskams;Steven Joniau;Hein Van Poppel.
International Journal of Cancer (2002)

409 Citations

Contribution of circulating lipids to the improved outcome of critical illness by glycemic control with intensive insulin therapy.

Dieter Mesotten;Johannes V. Swinnen;Frank Vanderhoydonc;Pieter J. Wouters.
The Journal of Clinical Endocrinology and Metabolism (2004)

380 Citations

Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells.

Annelies Beckers;Sophie Organe;Leen Timmermans;Katryn Scheys.
Cancer Research (2007)

380 Citations

RNA interference-mediated silencing of the acetyl-CoA-carboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells.

Koen Brusselmans;Ellen De Schrijver;Guido Verhoeven;Johannes V. Swinnen.
Cancer Research (2005)

379 Citations

RNA interference-mediated silencing of the fatty acid synthase gene attenuates growth and induces morphological changes and apoptosis of LNCaP prostate cancer cells.

Ellen De Schrijver;Koen Brusselmans;Walter Heyns;Guido Verhoeven.
Cancer Research (2003)

371 Citations

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