Johannes V. Swinnen

Overview

Best Publications

• EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research

  Jan Van Deun;Pieter Mestdagh;Patrizia Agostinis;Özden Akay

  1047
  Citations

• A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis.

  Karel De Gendt;Johannes V. Swinnen;Philippa T. K. Saunders;Luc Schoonjans

  914
  Citations

• Increased lipogenesis in cancer cells: new players, novel targets

  Johannes V Swinnen;Koen Brusselmans;Guido Verhoeven

  796
  Citations

• De novo Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation

  Evelien Rysman;Koen Brusselmans;Katryn Scheys;Leen Timmermans

  718
  Citations

• Induction of Cancer Cell Apoptosis by Flavonoids Is Associated with Their Ability to Inhibit Fatty Acid Synthase Activity

  Koen Brusselmans;Ruth Vrolix;Guido Verhoeven;Johannes V. Swinnen

  588
  Citations

• ATP-Citrate Lyase: A Key Player in Cancer Metabolism

  Nousheen Zaidi;Johannes V. Swinnen;Karine Smans

  521
  Citations

• Lipogenesis and lipolysis: the pathways exploited by the cancer cells to acquire fatty acids.

  Nousheen Zaidi;Leslie Lupien;Nancy B. Kuemmerle;William B. Kinlaw

  482
  Citations

• Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity

  Kim Vriens;Stefan Christen;Sweta Parik;Dorien Broekaert

  467
  Citations

• Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention

  Lisa M. Butler;Ylenia Perone;Jonas Dehairs;Leslie E. Lupien

  432
  Citations

• Overexpression of fatty acid synthase is an early and common event in the development of prostate cancer

  Johannes V. Swinnen;Tania Roskams;Steven Joniau;Hein Van Poppel

  429
  Citations

• Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells.

  Annelies Beckers;Sophie Organe;Leen Timmermans;Katryn Scheys

  409
  Citations

• RNA interference-mediated silencing of the acetyl-CoA-carboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells.

  Koen Brusselmans;Ellen De Schrijver;Guido Verhoeven;Johannes V. Swinnen

  395
  Citations

• Contribution of circulating lipids to the improved outcome of critical illness by glycemic control with intensive insulin therapy.

  Dieter Mesotten;Johannes V. Swinnen;Frank Vanderhoydonc;Pieter J. Wouters

  391
  Citations

• RNA interference-mediated silencing of the fatty acid synthase gene attenuates growth and induces morphological changes and apoptosis of LNCaP prostate cancer cells.

  Ellen De Schrijver;Koen Brusselmans;Walter Heyns;Guido Verhoeven

  380
  Citations

• Lipid metabolism in cancer: New perspectives and emerging mechanisms.

  Lindsay A. Broadfield;Antonino Alejandro Pane;Ali Talebi;Johannes V. Swinnen

  365
  Citations

• Coordinate regulation of lipogenic gene expression by androgens: Evidence for a cascade mechanism involving sterol regulatory element binding proteins

  Johannes V. Swinnen;William Ulrix;Walter Heyns;Guido Verhoeven

  348
  Citations

• Lipoprotein lipase links dietary fat to solid tumor cell proliferation

  Nancy B. Kuemmerle;Evelien Rysman;Portia S. Lombardo;Alison J. Flanagan

  322
  Citations

• Fatty acid synthase drives the synthesis of phospholipids partitioning into detergent-resistant membrane microdomains

  Johannes V Swinnen;Paul P Van Veldhoven;Leen Timmermans;Ellen De Schrijver

  318
  Citations

• Androgens stimulate fatty acid synthase in the human prostate cancer cell line LNCaP.

  Johannes V. Swinnen;Murielle Esquenet;Karine Goossens;Walter Heyns

  295
  Citations

• Role of the Phosphatidylinositol 3′-Kinase/PTEN/Akt Kinase Pathway in the Overexpression of Fatty Acid Synthase in LNCaP Prostate Cancer Cells

  Tine Van de Sande;Ellen De Schrijver;Walter Heyns;Guido Verhoeven

  283
  Citations