2023 - Research.com Biology and Biochemistry in Belgium Leader Award
Johannes V. Swinnen mainly investigates Biochemistry, Fatty acid synthase, LNCaP, Cancer cell and Cancer research. His Fatty acid synthase study incorporates themes from Carcinogenesis, Sterol Regulatory Element Binding Protein 1, Sterol regulatory element-binding protein and Prostate. As part of the same scientific family, Johannes V. Swinnen usually focuses on LNCaP, concentrating on Cell growth and intersecting with Programmed cell death.
The Cancer cell study combines topics in areas such as Lipogenesis, Lyase, Enzyme, Cell biology and Membrane lipids. His work carried out in the field of Cancer research brings together such families of science as Apoptosis, Fas receptor and Fas ligand. His Prostate cancer study integrates concerns from other disciplines, such as Testosterone, Androgen and Dihydrotestosterone.
His main research concerns Internal medicine, Cancer research, Endocrinology, Cell biology and Androgen receptor. Johannes V. Swinnen has included themes like Cell culture and Oncology in his Internal medicine study. Johannes V. Swinnen interconnects Cancer, Prostate cancer, Fatty acid synthase and Programmed cell death in the investigation of issues within Cancer research.
His Cell biology research integrates issues from Cancer cell and Cell, Cell type. Johannes V. Swinnen has researched Cancer cell in several fields, including Lipogenesis, Biochemistry, Cell growth, Lipid metabolism and CD36. His Androgen receptor research includes elements of Molecular biology, Receptor, Glucocorticoid receptor and Sertoli cell.
His primary areas of study are Cancer research, Cell biology, Prostate cancer, Lipid metabolism and Cancer cell. His studies in Cancer research integrate themes in fields like Androgen, Prostate, Metastasis and Bortezomib. His Cell biology research is multidisciplinary, incorporating elements of Lipogenesis, Endocytosis and Oxidative phosphorylation.
Johannes V. Swinnen does research in Prostate cancer, focusing on Androgen receptor specifically. His research on Lipid metabolism also deals with topics like
Johannes V. Swinnen mainly focuses on Cell biology, Lipid metabolism, Cancer cell, Cancer research and Downregulation and upregulation. His Cell biology research integrates issues from Lipogenesis and Endocytosis. His Lipogenesis study incorporates themes from Sterol regulatory element-binding protein, Kinase activity, Malonyl-CoA, Targeted therapy and Fatty acid synthesis.
He interconnects Membrane biogenesis, Metabolic adaptation and Fatty acid in the investigation of issues within Cancer cell. The Cancer research study combines topics in areas such as Ceramide, Sphingomyelin, Acid sphingomyelinase and Multiple myeloma, Bortezomib. His Cancer study combines topics from a wide range of disciplines, such as Cell culture, Biochemistry, Cell growth, Biosynthesis and Membrane lipids.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis.
Karel De Gendt;Johannes V. Swinnen;Philippa T. K. Saunders;Luc Schoonjans.
Proceedings of the National Academy of Sciences of the United States of America (2004)
Increased lipogenesis in cancer cells: new players, novel targets
Johannes V Swinnen;Koen Brusselmans;Guido Verhoeven.
Current Opinion in Clinical Nutrition and Metabolic Care (2006)
EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research
Jan Van Deun;Pieter Mestdagh;Patrizia Agostinis;Özden Akay.
Nature Methods (2017)
De novo Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation
Evelien Rysman;Koen Brusselmans;Katryn Scheys;Leen Timmermans.
Cancer Research (2010)
Induction of Cancer Cell Apoptosis by Flavonoids Is Associated with Their Ability to Inhibit Fatty Acid Synthase Activity
Koen Brusselmans;Ruth Vrolix;Guido Verhoeven;Johannes V. Swinnen.
Journal of Biological Chemistry (2005)
Overexpression of fatty acid synthase is an early and common event in the development of prostate cancer
Johannes V. Swinnen;Tania Roskams;Steven Joniau;Hein Van Poppel.
International Journal of Cancer (2002)
Contribution of circulating lipids to the improved outcome of critical illness by glycemic control with intensive insulin therapy.
Dieter Mesotten;Johannes V. Swinnen;Frank Vanderhoydonc;Pieter J. Wouters.
The Journal of Clinical Endocrinology and Metabolism (2004)
Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells.
Annelies Beckers;Sophie Organe;Leen Timmermans;Katryn Scheys.
Cancer Research (2007)
RNA interference-mediated silencing of the acetyl-CoA-carboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells.
Koen Brusselmans;Ellen De Schrijver;Guido Verhoeven;Johannes V. Swinnen.
Cancer Research (2005)
RNA interference-mediated silencing of the fatty acid synthase gene attenuates growth and induces morphological changes and apoptosis of LNCaP prostate cancer cells.
Ellen De Schrijver;Koen Brusselmans;Walter Heyns;Guido Verhoeven.
Cancer Research (2003)
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