What is he best known for?
The fields of study he is best known for:
His primary areas of study are Biochemistry, Phosphodiesterase, Cell biology, Cyclic nucleotide phosphodiesterase and PDE10A.
His Biochemistry study frequently links to adjacent areas such as Molecular biology.
His Phosphodiesterase research is multidisciplinary, relying on both Guanosine, Adenosine and Ligand.
Joseph A. Beavo combines subjects such as Regulatory T cell differentiation, Receptor, Regulation of gene expression and Cell cycle with his study of Cell biology.
In his study, which falls under the umbrella issue of Cyclic nucleotide phosphodiesterase, Zardaverine, Trequinsin, Cell type and Isozyme is strongly linked to Zaprinast.
His Signal transduction research includes themes of Internal medicine, Insulin, Endocrinology and Cyclic nucleotide.
His most cited work include:
- Cyclic Nucleotide Phosphodiesterases: Molecular Regulation to Clinical Use (1376 citations)
- Biochemistry and Physiology of Cyclic Nucleotide Phosphodiesterases: Essential Components in Cyclic Nucleotide Signaling (925 citations)
- Foxp3-dependent programme of regulatory T-cell differentiation (902 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Phosphodiesterase, Biochemistry, Internal medicine, Endocrinology and Molecular biology.
His Phosphodiesterase study integrates concerns from other disciplines, such as Nucleotide, Cyclic nucleotide and Cell biology.
His Cyclic nucleotide research includes elements of Effector and Second messenger system.
Biochemistry is a component of his Cyclic nucleotide phosphodiesterase, Enzyme, Calmodulin, Isozyme and Phosphodiesterase 3 studies.
His Cyclic nucleotide phosphodiesterase study incorporates themes from Peptide sequence and Protein domain.
His Molecular biology study combines topics in areas such as Complementary DNA, Messenger RNA, Gene and Zaprinast.
He most often published in these fields:
- Phosphodiesterase (63.55%)
- Biochemistry (56.16%)
- Internal medicine (19.70%)
What were the highlights of his more recent work (between 2008-2021)?
- Phosphodiesterase (63.55%)
- Internal medicine (19.70%)
- Endocrinology (18.72%)
In recent papers he was focusing on the following fields of study:
Joseph A. Beavo mainly investigates Phosphodiesterase, Internal medicine, Endocrinology, Protein kinase A and Biochemistry.
His research integrates issues of Nucleotide, Cyclic nucleotide, Signal transduction, Second messenger system and Phosphorylation in his study of Phosphodiesterase.
His studies examine the connections between Cyclic nucleotide and genetics, as well as such issues in Cell biology, with regards to Monocyte.
His Internal medicine research integrates issues from Isozyme and Cardiology.
His is involved in several facets of Biochemistry study, as is seen by his studies on PDE10A, PDE1, Enzyme, IBMX and Adenylyl cyclase.
He studied PDE1 and Calmodulin that intersect with Downregulation and upregulation and Cyclic nucleotide phosphodiesterase.
Between 2008 and 2021, his most popular works were:
- Role of Ca2+/Calmodulin-Stimulated Cyclic Nucleotide Phosphodiesterase 1 in Mediating Cardiomyocyte Hypertrophy (140 citations)
- Sildenafil reverses cardiac dysfunction in the mdx mouse model of Duchenne muscular dystrophy (138 citations)
- Sildenafil reduces respiratory muscle weakness and fibrosis in the mdx mouse model of Duchenne muscular dystrophy. (112 citations)
In his most recent research, the most cited papers focused on:
Joseph A. Beavo focuses on Internal medicine, Endocrinology, Phosphodiesterase, Protein kinase A and cGMP-specific phosphodiesterase type 5.
His biological study spans a wide range of topics, including Isozyme, Phosphorylation, Second messenger system, Myocyte and Corticosterone.
Joseph A. Beavo has included themes like Immunoprecipitation, Molecular biology, Activator and Binding site in his Phosphorylation study.
Cell biology and Receptor are the main areas of his Second messenger system studies.
His Myocyte research incorporates elements of Downregulation and upregulation, Cyclic adenosine monophosphate and Cyclic nucleotide phosphodiesterase.
The Angiotensin II study combines topics in areas such as PDE1, Calmodulin, Nitric oxide and Cyclic nucleotide.
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