D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 65 Citations 13,789 171 World Ranking 4137 National Ranking 327

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

George S. Baillie focuses on Phosphodiesterase, Protein kinase A, Cell biology, Signal transduction and Biochemistry. His Phosphodiesterase research is multidisciplinary, relying on both Molecular biology, Membrane, Intracellular, Kinase and Gene isoform. His Protein kinase A study improves the overall literature in Phosphorylation.

His Cell biology research includes elements of Receptor, Internal medicine, PDE4B and Endocrinology. His Signal transduction research incorporates themes from Plasma protein binding and Computational biology. In general Biochemistry, his work in Vesicle and Arginine is often linked to Aquaporin 2 and Reabsorption linking many areas of study.

His most cited work include:

  • DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling. (564 citations)
  • Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins. (444 citations)
  • β-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates β-adrenoceptor switching from Gs to Gi (333 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Cell biology, Phosphodiesterase, Protein kinase A, Biochemistry and Phosphorylation. George S. Baillie combines topics linked to Receptor with his work on Cell biology. George S. Baillie has researched Phosphodiesterase in several fields, including Endocrinology, Molecular biology, Internal medicine, Intracellular and Gene isoform.

His work is dedicated to discovering how Gene isoform, Neuroscience are connected with Disease and other disciplines. His Protein kinase A research incorporates elements of Beta-Arrestins, Signal transduction and Forskolin. The concepts of his Phosphorylation study are interwoven with issues in Heat shock protein, HEK 293 cells and Kinase.

He most often published in these fields:

  • Cell biology (44.79%)
  • Phosphodiesterase (33.59%)
  • Protein kinase A (27.80%)

What were the highlights of his more recent work (between 2016-2021)?

  • Cell biology (44.79%)
  • Phosphodiesterase (33.59%)
  • Phosphorylation (20.08%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Cell biology, Phosphodiesterase, Phosphorylation, Protein kinase A and Internal medicine. Cell biology and Receptor are frequently intertwined in his study. His Phosphodiesterase research is multidisciplinary, relying on both Arrestin, Cyclic nucleotide, Signal transduction, Disease and Gene isoform.

His study on MAPK/ERK pathway is often connected to Soluble adenylyl cyclase as part of broader study in Phosphorylation. His Protein kinase A research is multidisciplinary, incorporating elements of Cell, LYN, Allosteric regulation and Lipid microdomain. His biological study spans a wide range of topics, including Endocrinology and Oncology.

Between 2016 and 2021, his most popular works were:

  • Therapeutic targeting of 3',5'-cyclic nucleotide phosphodiesterases: inhibition and beyond. (67 citations)
  • PDE2A2 regulates mitochondria morphology and apoptotic cell death via local modulation of cAMP/PKA signalling (54 citations)
  • TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells (41 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

His primary areas of study are Cell biology, Phosphodiesterase, Phosphorylation, Protein kinase A and Gene isoform. His Cell biology study combines topics in areas such as HEK 293 cells and Bioinformatics. In his study, which falls under the umbrella issue of Phosphodiesterase, Small molecule, Intracellular, Allosteric regulation and Therapeutic targeting is strongly linked to Compartmentalization.

In general Phosphorylation study, his work on SOCS3, Janus kinase and Suppressor of cytokine signalling often relates to the realm of Cavin, thereby connecting several areas of interest. His Protein kinase A research incorporates themes from SUMO protein, DNA ligase and LYN. He has included themes like CAMP response element binding, Effective treatment, Disease and Activator in his Gene isoform study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling.

J. Kirsty Millar;Benjamin S. Pickard;Shaun Mackie;Rachel James.
Science (2005)

710 Citations

Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins.

Stephen J. Perry;George S. Baillie;Trudy A. Kohout;Ian McPhee.
Science (2002)

685 Citations

Matrix polymers of Candida biofilms and their possible role in biofilm resistance to antifungal agents

G S Baillie;L J Douglas.
Journal of Antimicrobial Chemotherapy (2000)

505 Citations

β-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates β-adrenoceptor switching from Gs to Gi

George S. Baillie;Arvind Sood;Ian McPhee;Irene Gall.
Proceedings of the National Academy of Sciences of the United States of America (2003)

427 Citations

Mixed species biofilms of Candida albicans and Staphylococcus epidermidis.

Berit Adam;George S. Baillie;L. Julia Douglas.
Journal of Medical Microbiology (2002)

386 Citations

Apremilast, a cAMP phosphodiesterase-4 inhibitor, demonstrates anti-inflammatory activity in vitro and in a model of psoriasis.

Schafer Ph;Parton A;Gandhi Ak;Capone L.
British Journal of Pharmacology (2010)

372 Citations

Role of dimorphism in the development of Candida albicans biofilms.

George S. Baillie;L. Julia Douglas.
Journal of Medical Microbiology (1999)

371 Citations

Sleep deprivation impairs cAMP signalling in the hippocampus

Christopher G. Vecsey;George S. Baillie;Devan Jaganath;Robbert Havekes.
Nature (2009)

369 Citations

cAMP-Specific phosphodiesterase-4 enzymes in the cardiovascular system: a molecular toolbox for generating compartmentalized cAMP signaling.

Miles D. Houslay;George S. Baillie;Donald H. Maurice.
Circulation Research (2007)

337 Citations

ERK2 mitogen-activated protein kinase binding, phosphorylation, and regulation of the PDE4D cAMP-specific phosphodiesterases. The involvement of COOH-terminal docking sites and NH2-terminal UCR regions.

Simon J. MacKenzie;George S. Baillie;Ian McPhee;Graeme B. Bolger.
Journal of Biological Chemistry (2000)

335 Citations

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