George S. Baillie focuses on Phosphodiesterase, Protein kinase A, Cell biology, Signal transduction and Biochemistry. His Phosphodiesterase research is multidisciplinary, relying on both Molecular biology, Membrane, Intracellular, Kinase and Gene isoform. His Protein kinase A study improves the overall literature in Phosphorylation.
His Cell biology research includes elements of Receptor, Internal medicine, PDE4B and Endocrinology. His Signal transduction research incorporates themes from Plasma protein binding and Computational biology. In general Biochemistry, his work in Vesicle and Arginine is often linked to Aquaporin 2 and Reabsorption linking many areas of study.
His primary scientific interests are in Cell biology, Phosphodiesterase, Protein kinase A, Biochemistry and Phosphorylation. George S. Baillie combines topics linked to Receptor with his work on Cell biology. George S. Baillie has researched Phosphodiesterase in several fields, including Endocrinology, Molecular biology, Internal medicine, Intracellular and Gene isoform.
His work is dedicated to discovering how Gene isoform, Neuroscience are connected with Disease and other disciplines. His Protein kinase A research incorporates elements of Beta-Arrestins, Signal transduction and Forskolin. The concepts of his Phosphorylation study are interwoven with issues in Heat shock protein, HEK 293 cells and Kinase.
His primary areas of investigation include Cell biology, Phosphodiesterase, Phosphorylation, Protein kinase A and Internal medicine. Cell biology and Receptor are frequently intertwined in his study. His Phosphodiesterase research is multidisciplinary, relying on both Arrestin, Cyclic nucleotide, Signal transduction, Disease and Gene isoform.
His study on MAPK/ERK pathway is often connected to Soluble adenylyl cyclase as part of broader study in Phosphorylation. His Protein kinase A research is multidisciplinary, incorporating elements of Cell, LYN, Allosteric regulation and Lipid microdomain. His biological study spans a wide range of topics, including Endocrinology and Oncology.
His primary areas of study are Cell biology, Phosphodiesterase, Phosphorylation, Protein kinase A and Gene isoform. His Cell biology study combines topics in areas such as HEK 293 cells and Bioinformatics. In his study, which falls under the umbrella issue of Phosphodiesterase, Small molecule, Intracellular, Allosteric regulation and Therapeutic targeting is strongly linked to Compartmentalization.
In general Phosphorylation study, his work on SOCS3, Janus kinase and Suppressor of cytokine signalling often relates to the realm of Cavin, thereby connecting several areas of interest. His Protein kinase A research incorporates themes from SUMO protein, DNA ligase and LYN. He has included themes like CAMP response element binding, Effective treatment, Disease and Activator in his Gene isoform study.
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DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling.
J. Kirsty Millar;Benjamin S. Pickard;Shaun Mackie;Rachel James.
Science (2005)
Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins.
Stephen J. Perry;George S. Baillie;Trudy A. Kohout;Ian McPhee.
Science (2002)
Matrix polymers of Candida biofilms and their possible role in biofilm resistance to antifungal agents
G S Baillie;L J Douglas.
Journal of Antimicrobial Chemotherapy (2000)
β-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates β-adrenoceptor switching from Gs to Gi
George S. Baillie;Arvind Sood;Ian McPhee;Irene Gall.
Proceedings of the National Academy of Sciences of the United States of America (2003)
Mixed species biofilms of Candida albicans and Staphylococcus epidermidis.
Berit Adam;George S. Baillie;L. Julia Douglas.
Journal of Medical Microbiology (2002)
Apremilast, a cAMP phosphodiesterase-4 inhibitor, demonstrates anti-inflammatory activity in vitro and in a model of psoriasis.
Schafer Ph;Parton A;Gandhi Ak;Capone L.
British Journal of Pharmacology (2010)
Role of dimorphism in the development of Candida albicans biofilms.
George S. Baillie;L. Julia Douglas.
Journal of Medical Microbiology (1999)
Sleep deprivation impairs cAMP signalling in the hippocampus
Christopher G. Vecsey;George S. Baillie;Devan Jaganath;Robbert Havekes.
Nature (2009)
cAMP-Specific phosphodiesterase-4 enzymes in the cardiovascular system: a molecular toolbox for generating compartmentalized cAMP signaling.
Miles D. Houslay;George S. Baillie;Donald H. Maurice.
Circulation Research (2007)
ERK2 mitogen-activated protein kinase binding, phosphorylation, and regulation of the PDE4D cAMP-specific phosphodiesterases. The involvement of COOH-terminal docking sites and NH2-terminal UCR regions.
Simon J. MacKenzie;George S. Baillie;Ian McPhee;Graeme B. Bolger.
Journal of Biological Chemistry (2000)
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