What is he best known for?
The fields of study he is best known for:
Miles D. Houslay mainly investigates Biochemistry, Phosphodiesterase, Cell biology, Protein kinase A and Signal transduction.
His research in Phosphodiesterase intersects with topics in Molecular biology, Kinase, Intracellular and Gene isoform.
His Cell biology research is multidisciplinary, incorporating perspectives in Receptor, Cell type and Flux.
His Receptor research includes themes of Endocrinology and Glucagon.
Miles D. Houslay works mostly in the field of Protein kinase A, limiting it down to concerns involving Rolipram and, occasionally, Mutant.
Miles D. Houslay has researched Signal transduction in several fields, including Plasma protein binding, Neuroscience and Signalling.
His most cited work include:
- PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization. (659 citations)
- DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling. (564 citations)
- Keynote review: Phosphodiesterase-4 as a therapeutic target (524 citations)
What are the main themes of his work throughout his whole career to date?
Miles D. Houslay mostly deals with Phosphodiesterase, Biochemistry, Cell biology, Internal medicine and Endocrinology.
His work deals with themes such as Molecular biology, Intracellular, Protein kinase A and Gene isoform, which intersect with Phosphodiesterase.
In his study, Adenylyl cyclase is inextricably linked to Forskolin, which falls within the broad field of Molecular biology.
His studies in Protein kinase A integrate themes in fields like Beta-Arrestins and MAPK/ERK pathway.
His study in Endocrinology is interdisciplinary in nature, drawing from both Adenylate kinase and G protein.
His studies deal with areas such as Glucagon receptor and Glucagon as well as Adenylate kinase.
He most often published in these fields:
- Phosphodiesterase (39.87%)
- Biochemistry (38.20%)
- Cell biology (27.97%)
What were the highlights of his more recent work (between 2010-2020)?
- Phosphodiesterase (39.87%)
- Cell biology (27.97%)
- Protein kinase A (19.83%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Phosphodiesterase, Cell biology, Protein kinase A, Phosphorylation and Neuroscience.
His Phosphodiesterase research incorporates elements of Cancer research, Molecular biology, Internal medicine, Intracellular and Gene isoform.
When carried out as part of a general Cell biology research project, his work on Scaffold protein, Phosphodiesterase 3, Kinase and RHOA is frequently linked to work in Low-affinity nerve growth factor receptor, therefore connecting diverse disciplines of study.
His Protein kinase A study incorporates themes from Endocrinology and Receptor, Signal transduction, Activator, Second messenger system.
His Phosphorylation study necessitates a more in-depth grasp of Biochemistry.
In most of his Biochemistry studies, his work intersects topics such as Biophysics.
Between 2010 and 2020, his most popular works were:
- DISC1-dependent switch from progenitor proliferation to migration in the developing cortex (159 citations)
- Integrating Cardiac PIP3 and cAMP Signaling through a PKA Anchoring Function of p110γ (152 citations)
- The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function (118 citations)
In his most recent research, the most cited papers focused on:
Miles D. Houslay mainly focuses on Cell biology, Protein kinase A, Signal transduction, Phosphodiesterase and Phosphorylation.
His Effector, Scaffold protein and Kinase study, which is part of a larger body of work in Cell biology, is frequently linked to Vascular endothelial growth factor A, bridging the gap between disciplines.
His work carried out in the field of Protein kinase A brings together such families of science as Myocyte, Endocrinology, Enzyme activator and Second messenger system.
Miles D. Houslay focuses mostly in the field of Endocrinology, narrowing it down to matters related to PRKAR1A and, in some cases, Internal medicine.
His Signal transduction study improves the overall literature in Biochemistry.
The Phosphodiesterase study combines topics in areas such as Molecular biology, Peptide and Prostate cancer, Androgen receptor.
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