Nicholas J. Brandon

Overview

Best Publications

• DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling.

  J. Kirsty Millar;Benjamin S. Pickard;Shaun Mackie;Rachel James

  772
  Citations

• GABA(A)-receptor-associated protein links GABA(A) receptors and the cytoskeleton.

  Hongbing Wang;Fiona K. Bedford;Nicholas J. Brandon;Stephen J. Moss

  738
  Citations

• Linking neurodevelopmental and synaptic theories of mental illness through DISC1

  Nicholas J. Brandon;Akira Sawa

  591
  Citations

• Activation of estrogen receptor-beta regulates hippocampal synaptic plasticity and improves memory.

  Feng Liu;Mark Day;Luis C Muñiz;Daniel Bitran

  590
  Citations

• Disrupted in Schizophrenia 1 Interactome : evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia

  L. M. Camargo;L. M. Camargo;V. Collura;J.-C. Rain;K. Mizuguchi

  511
  Citations

• Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1

  Akiko Hayashi-Takagi;Manabu Takaki;Nick Graziane;Saurav Seshadri

  493
  Citations

• Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis.

  Andrew E Jaffe;Richard E Straub;Joo Heon Shin;Ran Tao

  397
  Citations

• Neurodevelopmental mechanisms of schizophrenia: understanding disturbed postnatal brain maturation through neuregulin-1–ErbB4 and DISC1

  Hanna Jaaro-Peled;Akiko Hayashi-Takagi;Saurav Seshadri;Atsushi Kamiya

  371
  Citations

• Phosphodiesterase 10A inhibitor activity in preclinical models of the positive, cognitive, and negative symptoms of schizophrenia.

  Steven M. Grauer;Virginia L. Pulito;Rachel L. Navarra;Michele P. Kelly

  367
  Citations

• Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders.

  N.J Brandon;E.J Handford;I Schurov;J.-C Rain

  322
  Citations

• Cytoskeletal Changes Underlie Estrogen's Acute Effects on Synaptic Transmission and Plasticity

  Enikö A Kramár;Lulu Y Chen;Nicholas J Brandon;Christopher S Rex

  301
  Citations

• Schizophrenia-Related Neural and Behavioral Phenotypes in Transgenic Mice Expressing Truncated Disc1

  Sanbing Shen;Bing Lang;Chizu Nakamoto;Feng Zhang

  294
  Citations

• Evidence for sustained elevation of IL-6 in the CNS as a key contributor of depressive-like phenotypes.

  S J Sukoff Rizzo;S J Sukoff Rizzo;S J Neal;Z A Hughes;M Beyna

  262
  Citations

• ADX47273 [S-(4-fluoro-phenyl)-{3-[3-(4-fluoro-phenyl)-[1,2,4]-oxadiazol-5-yl]-piperidin-1-yl}-methanone]: a novel metabotropic glutamate receptor 5-selective positive allosteric modulator with preclinical antipsychotic-like and procognitive activities.

  Feng Liu;Steve Grauer;Cody Kelley;Rachel Navarra

  262
  Citations

• Understanding the Role of DISC1 in Psychiatric Disease and during Normal Development

  Nicholas J. Brandon;J. Kirsty Millar;Carsten Korth;Hazel Sive;Hazel Sive

  255
  Citations

• The genetics and biology of DISC1--an emerging role in psychosis and cognition.

  David J. Porteous;Pippa Thomson;Nicholas J. Brandon;J. Kirsty Millar

  239
  Citations

• Expression of disrupted in schizophrenia 1 (DISC1) protein in the adult and developing mouse brain indicates its role in neurodevelopment

  I L Schurov;E J Handford;N J Brandon;P J Whiting

  235
  Citations

• GABAA receptor phosphorylation and functional modulation in cortical neurons by a protein kinase C-dependent pathway.

  Nicholas J. Brandon;Patrick Delmas;Josef T. Kittler;Bernard J. McDonald

  233
  Citations

• Cell surface stability of gamma-aminobutyric acid type A receptors. Dependence on protein kinase C activity and subunit composition.

  Christopher N. Connolly;Josef T. Kittler;Philip Thomas;Julia M. Uren

  231
  Citations

• Dissecting transcriptomic signatures of neuronal differentiation and maturation using iPSCs

  Emily E. Burke;Joshua G. Chenoweth;Joo Heon Shin;Leonardo Collado-Torres

  190
  Citations

• Multiple roles of protein kinases in the modulation of gamma-aminobutyric acid(A) receptor function and cell surface expression.

  Nicholas J. Brandon;Jasmina N. Jovanovic;Stephen J. Moss

  176
  Citations