His primary areas of study are Cell biology, ADAM10, Sheddase, Molecular biology and Disintegrin. Dieter Hartmann has researched Cell biology in several fields, including ADAM17 Protein, Ectodomain and TGF alpha. As part of one scientific family, he deals mainly with the area of ADAM10, narrowing it down to issues related to the ADAM Proteins, and often Chemokine, Transmembrane protein and Cleavage.
His Sheddase course of study focuses on Amphiregulin and Heparin-binding EGF-like growth factor and ADAM9. His studies in Molecular biology integrate themes in fields like Enzyme activator, Ceramide and Protein kinase C, Rottlerin. His Disintegrin research is multidisciplinary, incorporating elements of Cytoplasm and Catenin.
Dieter Hartmann focuses on Cell biology, Molecular biology, Biochemistry, ADAM10 and Metachromatic leukodystrophy. Dieter Hartmann combines subjects such as Cell growth, Regulated Intramembrane Proteolysis, Ectodomain, Presenilin and Alpha secretase with his study of Cell biology. As a part of the same scientific study, Dieter Hartmann usually deals with the Molecular biology, concentrating on ADAM17 Protein and frequently concerns with TGF alpha and Signal transduction.
His Biochemistry study combines topics in areas such as P3 peptide and Neurodegeneration. The various areas that Dieter Hartmann examines in his ADAM10 study include Phorbol, ADAM Proteins and Sheddase. His study in Sheddase is interdisciplinary in nature, drawing from both Epidermal growth factor, Epidermal growth factor receptor and Amphiregulin.
The scientist’s investigation covers issues in Cell biology, Myelin, Sphingolipid, Biochemistry and Molecular biology. His Cell biology research includes elements of Regulated Intramembrane Proteolysis, Sheddase, APH-1, ADAM10 and Alpha secretase. His biological study deals with issues like Genetics, which deal with fields such as Astrogliosis.
His studies deal with areas such as Endocrinology, Lipid metabolism, Ceramide synthase, Ceramide synthase 2 and Epidermis as well as Sphingolipid. His Biochemistry study combines topics from a wide range of disciplines, such as Cerebellum and Neurodegeneration. His Molecular biology research incorporates elements of Amino acid, Receptor, Peptide sequence, Alzheimer's disease and Amyloid precursor protein secretase.
His main research concerns Cell biology, Biochemistry, Alpha secretase, Presenilin and ADAM10. Dieter Hartmann is studying Endoplasmic reticulum, which is a component of Cell biology. His research in Endoplasmic reticulum tackles topics such as Calpain which are related to areas like Signal transduction.
He has included themes like Regulated Intramembrane Proteolysis, APH-1, Sheddase and Ectodomain in his Alpha secretase study. His work is dedicated to discovering how Cerebellum, Ceramide synthase are connected with Myelin and Cerebellar Degeneration and other disciplines. His research integrates issues of Intestinal mucosa, Inflammation, TGF alpha, Molecular biology and Metalloproteinase in his study of Tumor necrosis factor alpha.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands
Umut Sahin;Gisela Weskamp;Kristine Kelly;Kristine Kelly;Hong-Ming Zhou.
Journal of Cell Biology (2004)
Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice
Yoshitaka Tanaka;Yoshitaka Tanaka;Gundula Guhde;Anke Suter;Eeva Liisa Eskelinen;Eeva Liisa Eskelinen;Eeva Liisa Eskelinen.
The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts.
Dieter Hartmann;Bart De Strooper;Lutgarde Serneels;Kathleen Craessaerts.
Human Molecular Genetics (2002)
Mitochondrial Rhomboid PARL Regulates Cytochrome c Release during Apoptosis via OPA1-Dependent Cristae Remodeling
Sara Cipolat;Tomasz Rudka;Dieter Hartmann;Veronica Costa.
ADAM10 cleavage of N‐cadherin and regulation of cell–cell adhesion and β‐catenin nuclear signalling
Karina Reiss;Thorsten Maretzky;Andreas Ludwig;Thomas Tousseyn.
The EMBO Journal (2005)
The transmembrane CXC-chemokine ligand 16 is induced by IFN-gamma and TNF-alpha and shed by the activity of the disintegrin-like metalloproteinase ADAM10.
Soeren Abel;Christian Hundhausen;Rolf Mentlein;Alexander Schulte.
Journal of Immunology (2004)
Cellular Cholesterol Depletion Triggers Shedding of the Human Interleukin-6 Receptor by ADAM10 and ADAM17 (TACE)
Vance Matthews;Björn Schuster;Stefan Schütze;Ingo Bussmeyer.
Journal of Biological Chemistry (2003)
Phenotypic and Biochemical Analyses of BACE1- and BACE2-deficient Mice
Diana Dominguez;Jos Tournoy;Dieter Hartmann;Tobias Huth.
Journal of Biological Chemistry (2005)
Lipids revert inert Aβ amyloid fibrils to neurotoxic protofibrils that affect learning in mice
Ivo Cristiano Martins;Inna Kuperstein;Hannah Wilkinson;Elke Maes.
The EMBO Journal (2008)
The disintegrins ADAM10 and TACE contribute to the constitutive and phorbol ester-regulated normal cleavage of the cellular prion protein.
Bruno Vincent;Erwan Paitel;Paul Saftig;Yveline Frobert.
Journal of Biological Chemistry (2001)
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