Dieter Hartmann

Overview

Best Publications

• Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands

  Umut Sahin;Gisela Weskamp;Kristine Kelly;Kristine Kelly;Hong-Ming Zhou

  1198
  Citations

• Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice

  Yoshitaka Tanaka;Yoshitaka Tanaka;Gundula Guhde;Anke Suter;Eeva Liisa Eskelinen;Eeva Liisa Eskelinen;Eeva Liisa Eskelinen

  1089
  Citations

• The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts.

  Dieter Hartmann;Bart De Strooper;Lutgarde Serneels;Kathleen Craessaerts

  868
  Citations

• Mitochondrial Rhomboid PARL Regulates Cytochrome c Release during Apoptosis via OPA1-Dependent Cristae Remodeling

  Sara Cipolat;Tomasz Rudka;Dieter Hartmann;Veronica Costa

  868
  Citations

• ADAM10 mediates E-cadherin shedding and regulates epithelial cell-cell adhesion, migration, and beta-catenin translocation.

  Thorsten Maretzky;Karina Reiss;Andreas Ludwig;Julian Buchholz

  836
  Citations

• The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion.

  Christian Hundhausen;Dominika Misztela;Theo A. Berkhout;Neil Broadway

  817
  Citations

• Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency

  An Herreman;Dieter Hartmann;Wim Annaert;Paul Saftig

  753
  Citations

• ADAM10 cleavage of N‐cadherin and regulation of cell–cell adhesion and β‐catenin nuclear signalling

  Karina Reiss;Thorsten Maretzky;Andreas Ludwig;Thomas Tousseyn

  608
  Citations

• The transmembrane CXC-chemokine ligand 16 is induced by IFN-gamma and TNF-alpha and shed by the activity of the disintegrin-like metalloproteinase ADAM10.

  Soeren Abel;Christian Hundhausen;Rolf Mentlein;Alexander Schulte

  515
  Citations

• Cellular Cholesterol Depletion Triggers Shedding of the Human Interleukin-6 Receptor by ADAM10 and ADAM17 (TACE)

  Vance Matthews;Björn Schuster;Stefan Schütze;Ingo Bussmeyer

  494
  Citations

• Phenotypic and Biochemical Analyses of BACE1- and BACE2-deficient Mice

  Diana Dominguez;Jos Tournoy;Dieter Hartmann;Tobias Huth

  449
  Citations

• Lipids revert inert Aβ amyloid fibrils to neurotoxic protofibrils that affect learning in mice

  Ivo Cristiano Martins;Inna Kuperstein;Hannah Wilkinson;Elke Maes

  395
  Citations

• Substrate Selectivity of Epidermal Growth Factor-Receptor Ligand Sheddases and their Regulation by Phorbol Esters and Calcium Influx

  Keisuke Horiuchi;Keisuke Horiuchi;Sylvain Le Gall;Marc Schulte;Takafumi Yamaguchi

  368
  Citations

• The Disintegrins ADAM10 and TACE Contribute to the Constitutive and Phorbol Ester-regulated Normal Cleavage of the Cellular Prion Protein *

  Bruno Vincent;Erwan Paitel;Paul Saftig;Yveline Frobert

  367
  Citations

• Cell–matrix interaction via CD44 is independently regulated by different metalloproteinases activated in response to extracellular Ca2+ influx and PKC activation

  Osamu Nagano;Daizo Murakami;Dieter Hartmann;Bart De Strooper

  357
  Citations

• Role of endoplasmic reticulum depletion and multidomain proapoptotic BAX and BAK proteins in shaping cell death after hypericin-mediated photodynamic therapy

  Esther Buytaert;Geert Callewaert;Nico Hendrickx;Luca Scorrano

  323
  Citations

• Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice

  Athena Chalaris;Nina Adam;Christian Sina;Philip Rosenstiel

  321
  Citations

• Disturbed Cholesterol Traffic but Normal Proteolytic Function in LAMP-1/LAMP-2 Double-deficient Fibroblasts

  Eeva Liisa Eskelinen;Christine Katrin Schmidt;Silja Neu;Marion Willenborg

  309
  Citations

• Adult ceramide synthase 2 (CerS2) deficient mice exhibit myelin sheath defects, cerebellar degeneration and hepatocarcinomas

  Silke Imgrund;Dieter Hartmann;Hany Farwanah;Matthias Eckhardt

  291
  Citations

• L1 Is Sequentially Processed by Two Differently Activated Metalloproteases and Presenilin/γ-Secretase and Regulates Neural Cell Adhesion, Cell Migration, and Neurite Outgrowth

  Thorsten Maretzky;Marc Schulte;Andreas Ludwig;Stefan Rose-John

  288
  Citations