What is he best known for?
The fields of study he is best known for:
His primary areas of study are Cell biology, ADAM10, Sheddase, Molecular biology and Disintegrin.
Dieter Hartmann has researched Cell biology in several fields, including ADAM17 Protein, Ectodomain and TGF alpha.
As part of one scientific family, he deals mainly with the area of ADAM10, narrowing it down to issues related to the ADAM Proteins, and often Chemokine, Transmembrane protein and Cleavage.
His Sheddase course of study focuses on Amphiregulin and Heparin-binding EGF-like growth factor and ADAM9.
His studies in Molecular biology integrate themes in fields like Enzyme activator, Ceramide and Protein kinase C, Rottlerin.
His Disintegrin research is multidisciplinary, incorporating elements of Cytoplasm and Catenin.
His most cited work include:
- Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands (800 citations)
- Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice (713 citations)
- Mitochondrial Rhomboid PARL Regulates Cytochrome c Release during Apoptosis via OPA1-Dependent Cristae Remodeling (584 citations)
What are the main themes of his work throughout his whole career to date?
Dieter Hartmann focuses on Cell biology, Molecular biology, Biochemistry, ADAM10 and Metachromatic leukodystrophy.
Dieter Hartmann combines subjects such as Cell growth, Regulated Intramembrane Proteolysis, Ectodomain, Presenilin and Alpha secretase with his study of Cell biology.
As a part of the same scientific study, Dieter Hartmann usually deals with the Molecular biology, concentrating on ADAM17 Protein and frequently concerns with TGF alpha and Signal transduction.
His Biochemistry study combines topics in areas such as P3 peptide and Neurodegeneration.
The various areas that Dieter Hartmann examines in his ADAM10 study include Phorbol, ADAM Proteins and Sheddase.
His study in Sheddase is interdisciplinary in nature, drawing from both Epidermal growth factor, Epidermal growth factor receptor and Amphiregulin.
He most often published in these fields:
- Cell biology (51.69%)
- Molecular biology (20.22%)
- Biochemistry (17.98%)
What were the highlights of his more recent work (between 2008-2021)?
- Cell biology (51.69%)
- Myelin (11.24%)
- Sphingolipid (11.24%)
In recent papers he was focusing on the following fields of study:
The scientist’s investigation covers issues in Cell biology, Myelin, Sphingolipid, Biochemistry and Molecular biology.
His Cell biology research includes elements of Regulated Intramembrane Proteolysis, Sheddase, APH-1, ADAM10 and Alpha secretase.
His biological study deals with issues like Genetics, which deal with fields such as Astrogliosis.
His studies deal with areas such as Endocrinology, Lipid metabolism, Ceramide synthase, Ceramide synthase 2 and Epidermis as well as Sphingolipid.
His Biochemistry study combines topics from a wide range of disciplines, such as Cerebellum and Neurodegeneration.
His Molecular biology research incorporates elements of Amino acid, Receptor, Peptide sequence, Alzheimer's disease and Amyloid precursor protein secretase.
Between 2008 and 2021, his most popular works were:
- Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice (216 citations)
- Adult ceramide synthase 2 (CerS2) deficient mice exhibit myelin sheath defects, cerebellar degeneration and hepatocarcinomas (193 citations)
- ADAM10, the Rate-limiting Protease of Regulated Intramembrane Proteolysis of Notch and Other Proteins, Is Processed by ADAMS-9, ADAMS-15, and the γ-Secretase * (141 citations)
In his most recent research, the most cited papers focused on:
His main research concerns Cell biology, Biochemistry, Alpha secretase, Presenilin and ADAM10.
Dieter Hartmann is studying Endoplasmic reticulum, which is a component of Cell biology.
His research in Endoplasmic reticulum tackles topics such as Calpain which are related to areas like Signal transduction.
He has included themes like Regulated Intramembrane Proteolysis, APH-1, Sheddase and Ectodomain in his Alpha secretase study.
His work is dedicated to discovering how Cerebellum, Ceramide synthase are connected with Myelin and Cerebellar Degeneration and other disciplines.
His research integrates issues of Intestinal mucosa, Inflammation, TGF alpha, Molecular biology and Metalloproteinase in his study of Tumor necrosis factor alpha.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
