Member of the Association of American Physicians
Carl P. Blobel mostly deals with Cell biology, Disintegrin, Biochemistry, Sheddase and Metalloproteinase. His work deals with themes such as Cell adhesion, Neural cell adhesion molecule, ADAM17 Protein and ADAM10, which intersect with Cell biology. His Sheddase research incorporates themes from Epidermal growth factor, Epidermal growth factor receptor and Cancer research.
Carl P. Blobel has researched Epidermal growth factor in several fields, including Molecular biology and Growth factor. His biological study spans a wide range of topics, including Tumor necrosis factor alpha, Cell culture and Ectodomain. His study explores the link between Ectodomain and topics such as ADAM9 that cross with problems in ADAM Proteins and Myoblast fusion.
His primary scientific interests are in Cell biology, Metalloproteinase, Disintegrin, Ectodomain and ADAM10. Carl P. Blobel interconnects Molecular biology, ADAM17 Protein and Sheddase in the investigation of issues within Cell biology. His Sheddase research focuses on subjects like Epidermal growth factor receptor, which are linked to Transforming growth factor.
His Metalloproteinase study integrates concerns from other disciplines, such as Tumor necrosis factor alpha, Cancer research and Transmembrane domain. His work in the fields of Disintegrin, such as ADAM Proteins, intersects with other areas such as Secretory pathway. His study in Ectodomain is interdisciplinary in nature, drawing from both Betacellulin, Epidermal growth factor, Regulator and ADAM9.
The scientist’s investigation covers issues in Cell biology, ADAM10, Metalloproteinase, Disintegrin and Notch signaling pathway. Specifically, his work in Cell biology is concerned with the study of Signal transduction. His research in ADAM10 intersects with topics in Proinflammatory cytokine, Cell signaling, Sheddase and Tumor necrosis factor alpha.
Carl P. Blobel has included themes like Cancer research and Epidermal growth factor receptor in his Metalloproteinase study. His studies in Disintegrin integrate themes in fields like Transmembrane domain, Epidermal growth factor, Ectodomain and Transmembrane protein. His work carried out in the field of Ectodomain brings together such families of science as Matrix metalloproteinase and ADAM9.
Carl P. Blobel mainly investigates ADAM10, Cell biology, Notch signaling pathway, Angiogenesis and Endothelium. His ADAM10 research includes themes of Signal transduction and Immunology. The Angiogenesis study combines topics in areas such as Cell, Downregulation and upregulation, Homeostasis and Kidney development.
His Downregulation and upregulation study which covers Autoimmunity that intersects with Metalloproteinase. Carl P. Blobel integrates Metalloproteinase with Amyloid precursor protein secretase in his study. His Endothelium research is multidisciplinary, relying on both Regulator and Transcriptome.
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ADAMs: key components in EGFR signalling and development
Carl P. Blobel.
Nature Reviews Molecular Cell Biology (2005)
Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands
Umut Sahin;Gisela Weskamp;Kristine Kelly;Kristine Kelly;Hong-Ming Zhou.
Journal of Cell Biology (2004)
A potential fusion peptide and an integrin ligand domain in a protein active in sperm-egg fusion.
Carl P. Blobel;Tyra G. Wolfsberg;Christoph W. Turck;Diana G. Myles.
Metalloprotease-disintegrins: modular proteins capable of promoting cell-cell interactions and triggering signals by protein-ectodomain shedding.
Johannes Schlöndorff;Carl P. Blobel.
Journal of Cell Science (1999)
Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates the cleavage and shedding of fractalkine (CX3CL1).
Kyle J. Garton;Peter J. Gough;Carl P. Blobel;Gillian Murphy.
Journal of Biological Chemistry (2001)
Evidence for a Role of a Tumor Necrosis Factor-α (TNF-α)-converting Enzyme-like Protease in Shedding of TRANCE, a TNF Family Member Involved in Osteoclastogenesis and Dendritic Cell Survival
Lawrence Lum;Brian R. Wong;Régis Josien;J. David Becherer.
Journal of Biological Chemistry (1999)
Metalloprotease-Disintegrins: Links to Cell Adhesion and Cleavage of TNFα and Notch
Carl P Blobel.
Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans.
Peter Warwick Janes;Nayanendu Saha;William A Barton;Momchil V Kolev.
Intracellular maturation and localization of the tumour necrosis factor alpha convertase (TACE).
J Schlöndorff;J D Becherer;C P Blobel.
Biochemical Journal (2000)
Metalloprotease-Disintegrin MDC9: Intracellular Maturation and Catalytic Activity
Monireh Roghani;J. David Becherer;Marcia L. Moss;Ruth E. Atherton.
Journal of Biological Chemistry (1999)
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