Carl P. Blobel

Research.com Recognitions

• Member of the Association of American Physicians
• Member of the Association of American Physicians
• Member of the Association of American Physicians

Overview

Best Publications

• ADAMs: key components in EGFR signalling and development

  Carl P. Blobel

  1539
  Citations

• Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands

  Umut Sahin;Gisela Weskamp;Kristine Kelly;Kristine Kelly;Hong-Ming Zhou

  1198
  Citations

• A potential fusion peptide and an integrin ligand domain in a protein active in sperm-egg fusion.

  Carl P. Blobel;Tyra G. Wolfsberg;Christoph W. Turck;Diana G. Myles

  921
  Citations

• Metalloprotease-disintegrins: modular proteins capable of promoting cell-cell interactions and triggering signals by protein-ectodomain shedding.

  Johannes Schlöndorff;Carl P. Blobel

  813
  Citations

• Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates the cleavage and shedding of fractalkine (CX3CL1).

  Kyle J. Garton;Peter J. Gough;Carl P. Blobel;Gillian Murphy

  794
  Citations

• Evidence for a Role of a Tumor Necrosis Factor-α (TNF-α)-converting Enzyme-like Protease in Shedding of TRANCE, a TNF Family Member Involved in Osteoclastogenesis and Dendritic Cell Survival

  Lawrence Lum;Brian R. Wong;Régis Josien;J. David Becherer

  622
  Citations

• Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans.

  Peter Warwick Janes;Nayanendu Saha;William A Barton;Momchil V Kolev

  560
  Citations

• Metalloprotease-Disintegrins: Links to Cell Adhesion and Cleavage of TNFα and Notch

  Carl P Blobel

  536
  Citations

• Intracellular maturation and localization of the tumour necrosis factor alpha convertase (TACE).

  J Schlöndorff;J D Becherer;C P Blobel

  488
  Citations

• Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization.

  Haixia Xu;Jimmy Zhu;Sinead Smith;Julia Foldi

  486
  Citations

• The Disintegrin/Metalloproteinase ADAM10 Is Essential for the Establishment of the Brain Cortex

  Ellen Jorissen;Johannes Prox;Christian Bernreuther;Silvio Weber

  425
  Citations

• Metalloprotease-Disintegrin MDC9: Intracellular Maturation and Catalytic Activity

  Monireh Roghani;J. David Becherer;Marcia L. Moss;Ruth E. Atherton

  420
  Citations

• In search of partners: linking extracellular proteases to substrates

  Christopher M. Overall;Carl P. Blobel

  382
  Citations

• iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS.

  David R. McIlwain;Philipp A. Lang;Philipp A. Lang;Thorsten Maretzky;Koichi Hamada

  375
  Citations

• Cutting Edge: TNF-α-Converting Enzyme (TACE/ADAM17) Inactivation in Mouse Myeloid Cells Prevents Lethality from Endotoxin Shock

  Keisuke Horiuchi;Tokuhiro Kimura;Takeshi Miyamoto;Hironari Takaishi

  372
  Citations

• Substrate Selectivity of Epidermal Growth Factor-Receptor Ligand Sheddases and their Regulation by Phorbol Esters and Calcium Influx

  Keisuke Horiuchi;Keisuke Horiuchi;Sylvain Le Gall;Marc Schulte;Takafumi Yamaguchi

  368
  Citations

• ADAMs 10 and 17 Represent Differentially Regulated Components of a General Shedding Machinery for Membrane Proteins Such as Transforming Growth Factor α, L-Selectin, and Tumor Necrosis Factor α

  Sylvain M. Le Gall;Pierre Bobé;Karina Reiss;Keisuke Horiuchi

  356
  Citations

• Identification of a binding site in the disintegrin domain of fertilin required for sperm-egg fusion

  Diana G. Myles;Lida H. Kimmel;Carl P. Blobel;Judith M. White

  342
  Citations

• ADAM10 Regulates Endothelial Permeability and T-Cell Transmigration by Proteolysis of Vascular Endothelial Cadherin

  Beate Schulz;Jessica Pruessmeyer;Thorsten Maretzky;Andreas Ludwig

  338
  Citations

• Remarkable roles of proteolysis on and beyond the cell surface.

  Carl P Blobel

  338
  Citations