Lawrence G. Lum mainly investigates Cell biology, Signal transduction, Bone marrow, Wnt signaling pathway and Cellular differentiation. His biological study spans a wide range of topics, including Molecular biology and Metalloproteinase. His Signal transduction research focuses on Tissue homeostasis and how it connects with Anatomy.
Bone marrow is a subfield of Immunology that Lawrence G. Lum investigates. His Immunology research includes themes of Autoimmune neutropenia and Neutropenia. His study explores the link between Surgery and topics such as Gastroenterology that cross with problems in Internal medicine, Methotrexate, Prospective cohort study, Cumulative incidence and Pharmacotherapy.
Lawrence G. Lum focuses on Immunology, Cancer research, Internal medicine, Cell biology and Antibody. His studies deal with areas such as Cytotoxic T cell and Peripheral blood mononuclear cell as well as Immunology. His research in Cancer research focuses on subjects like T cell, which are connected to CD3.
His studies examine the connections between Internal medicine and genetics, as well as such issues in Gastroenterology, with regards to Cumulative incidence. Many of his studies involve connections with topics such as Tissue homeostasis and Cell biology. His work deals with themes such as Pokeweed mitogen, Antigen and Virology, which intersect with Antibody.
His main research concerns Cancer research, Internal medicine, Immunology, Cell biology and Wnt signaling pathway. His Cancer research research includes elements of Tumor microenvironment, Cancer, Breast cancer and Cytotoxicity. His Internal medicine study integrates concerns from other disciplines, such as Gastroenterology, Surgery and Oncology.
In his study, Granulocyte macrophage colony-stimulating factor and Cyclophosphamide is inextricably linked to Stem cell, which falls within the broad field of Immunology. His primary area of study in Cell biology is in the field of Signal transduction. Lawrence G. Lum has researched Wnt signaling pathway in several fields, including Cell signaling and Acyltransferase.
Lawrence G. Lum mostly deals with Cancer research, Wnt signaling pathway, Cell biology, Immunology and Immunotherapy. His work carried out in the field of Cancer research brings together such families of science as Breast cancer, Stem cell, Gene knockdown and RNA interference. The various areas that Lawrence G. Lum examines in his Wnt signaling pathway study include Cell signaling, Tissue homeostasis and Zebrafish.
The concepts of his Cell biology study are interwoven with issues in Cellular differentiation, Cancer cell, HEK 293 cells, Regulation of gene expression and Cell fate determination. His Immunology study incorporates themes from Peripheral blood mononuclear cell and Internal medicine, Transplantation. His Immunotherapy research integrates issues from Cell culture, T cell, Bispecific antibody, Monoclonal antibody and Interleukin 2.
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Methotrexate and Cyclosporine Compared with Cyclosporine Alone for Prophylaxis of Acute Graft versus Host Disease after Marrow Transplantation for Leukemia
Rainer Storb;H. Joachim Deeg;John Whitehead;Frederick Appelbaum.
The New England Journal of Medicine (1986)
Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer
Baozhi Chen;Michael E. Dodge;Wei Tang;Jianming Lu.
Nature Chemical Biology (2009)
The Hedgehog response network: sensors, switches, and routers.
Lawrence Lum;Philip A. Beachy.
Identification of Hedgehog Pathway Components by RNAi in Drosophila Cultured Cells
Lawrence Lum;Shenqin Yao;Brian Mozer;Alessandra Rovescalli.
Evidence for a Role of a Tumor Necrosis Factor-α (TNF-α)-converting Enzyme-like Protease in Shedding of TRANCE, a TNF Family Member Involved in Osteoclastogenesis and Dendritic Cell Survival
Lawrence Lum;Brian R. Wong;Régis Josien;J. David Becherer.
Journal of Biological Chemistry (1999)
Minimizing the risk of reporting false positives in large-scale RNAi screens
Christophe J Echeverri;Philip A Beachy;Buzz Baum;Michael Boutros.
Nature Methods (2006)
The kinetics of immune reconstitution after human marrow transplantation.
Lawrence G. Lum.
Leukemia of Large Granular Lymphocytes: Association with Clonal Chromosomal Abnormalities and Autoimmune Neutropenia, Thrombocytopenia, and Hemolytic Anemia
Thomas P. Loughran;Marshall E. Kadin;Gordon Starkebaum;Janis L. Abkowitz.
Annals of Internal Medicine (1985)
Prevalence of off-target effects in Drosophila RNA interference screens
Yong Ma;Adrian Creanga;Adrian Creanga;Lawrence Lum;Philip A. Beachy;Philip A. Beachy.
Hedgehog signal transduction via Smoothened association with a cytoplasmic complex scaffolded by the atypical kinesin, Costal-2.
Lawrence Lum;Chi Zhang;Sekyung Oh;Randall K. Mann.
Molecular Cell (2003)
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