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Immunology

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84
Citations
25658
World Ranking
1373
National Ranking
705

Medicine

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85
Citations
25803
World Ranking
14637
National Ranking
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Overview

Thomas P. Loughran is affiliated with the University of Virginia in the United States. Their research primarily focuses on medicine, with significant work in biochemistry, genetics, and molecular biology.

The scientist has contributed extensively to multiple subfields, including molecular biology, pathology and forensic medicine, genetics, immunology, and hematology. Their research covers key topics such as lymphoma diagnosis and treatment, chronic lymphocytic leukemia, acute myeloid leukemia, sphingolipid metabolism and signaling, immune cell function and interaction, histone deacetylase inhibitors, immunodeficiency, and autoimmune disorders.

Thomas P. Loughran has published in several prominent scientific journals. Frequent publication venues include:

  • Blood
  • Clinical Lymphoma Myeloma & Leukemia
  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancers

Collaborations have been an integral part of their work, with frequent co-authors including:

  • David J. Feith
  • Su-Fern Tan
  • Todd E. Fox
  • Johnson Ung
  • Aakrosh Ratan

Selected recent papers provide insight into the scope of their research contributions:

  • Differences in Breast and Colorectal Cancer Screening Adherence Among Women Residing in Urban and Rural Communities in the United States, 2021, JAMA Network Open
  • Advances in the Diagnosis and Treatment of Large Granular Lymphocytic Leukemia, 2020, Current Hematologic Malignancy Reports
  • Genomic landscape of TCRαβ and TCRγδ T-large granular lymphocyte leukemia, 2022, Blood
  • Frequent somatic TET2 mutations in chronic NK-LGL leukemia with distinct patterns of cytopenias, 2021, Blood
  • Single-cell characterization of leukemic and non-leukemic immune repertoires in CD8+ T-cell large granular lymphocytic leukemia, 2022, Nature Communications

Best Publications

  • Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia

    Hagop M Kantarjian;Charles Sawyers;Andreas Hochhaus;Francois Guilhot

  • Clonal Diseases of Large Granular Lymphocytes

    Thomas P. Loughran

  • Chronic graft-versus-host disease and other late complications of bone marrow transplantation.

    K M Sullivan;E Agura;C Anasetti;F Appelbaum

  • Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression

    P. K. Epling-Burnette;Jin Hong Liu;Robyn Catlett-Falcone;James Turkson

  • Somatic STAT3 Mutations in Large Granular Lymphocytic Leukemia

    Hanna L.M. Koskela;Samuli Eldfors;Pekka Ellonen;Arjan J. van Adrichem

  • The Lymphoproliferative Disease of Granular Lymphocytes: Updated Criteria for Diagnosis

    Gianpietro Semenzato;Renato Zambello;Gordon Starkebaum;Kazuo Oshimi

  • STAT3 mutations unify the pathogenesis of chronic lymphoproliferative disorders of NK cells and T-cell large granular lymphocyte leukemia

    Andres Jerez;Michael J. Clemente;Hideki Makishima;Hanna Koskela

  • Network model of survival signaling in large granular lymphocyte leukemia

    Ranran Zhang;Mithun Vinod Shah;Jun Yang;Susan B. Nyland

  • Leukemia of Large Granular Lymphocytes: Association with Clonal Chromosomal Abnormalities and Autoimmune Neutropenia, Thrombocytopenia, and Hemolytic Anemia

    Thomas P. Loughran;Marshall E. Kadin;Gordon Starkebaum;Janis L. Abkowitz

  • Microarray results: how accurate are they?

    Ravi Kothapalli;Sean J. Yoder;Shrikant M. Mane;Thomas P. Loughran

  • Large granular lymphocyte leukemia

    Lubomir Sokol;Thomas P. Loughran

  • How I treat LGL leukemia

    Thierry Lamy;Thomas P. Loughran

  • Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia

    Hanna L. M. Rajala;Samuli Eldfors;Heikki Kuusanmäki;Arjan J. van Adrichem

  • LGL leukemia: from pathogenesis to treatment

    Thierry Lamy;Aline Moignet;Thomas P. Loughran

  • Clinical features of large granular lymphocyte leukemia

    Thierry Lamy;Thomas P. Loughran

  • Large granular lymphocyte leukemia. Report of 38 cases and review of the literature.

    Thomas P. Loughran;Gordon Starkebaum

  • Current concepts: large granular lymphocyte leukemia

    T. Lamy;T.P. Loughran

  • Dysregulation of sphingolipid metabolism in cancer

    Lindsay K Ryland;Todd E Fox;Xin Liu;Thomas P Loughran

  • Network modeling of TGFβ signaling in hepatocellular carcinoma epithelial-to-mesenchymal transition reveals joint Sonic hedgehog and Wnt pathway activation

    Steven Nathaniel Steinway;Jorge Gomez Tejeda Zañudo;Wei Ding;Carl Bart Rountree

  • Cooperative regulation of Mcl-1 by Janus kinase/stat and phosphatidylinositol 3-kinase contribute to granulocyte-macrophage colony-stimulating factor-delayed apoptosis in human neutrophils

    P. K. Epling-Burnette;Bin Zhong;Fanqi Bai;Kun Jiang

Frequent Co-Authors

Jaroslaw P. Maciejewski
Jaroslaw P. Maciejewski Cleveland Clinic
Hong-Gang Wang
Hong-Gang Wang Pennsylvania State University
Xin Liu
Xin Liu Chinese Academy of Sciences
Sheng Wei
Sheng Wei University of South Florida
Satu Mustjoki
Satu Mustjoki University of Helsinki
Shantu Amin
Shantu Amin Pennsylvania State University
Alan F. List
Alan F. List Precision BioSciences
Julie Y. Djeu
Julie Y. Djeu University of South Florida
Myles C. Cabot
Myles C. Cabot East Carolina University
Kimmo Porkka
Kimmo Porkka University of Helsinki

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