Shantu Amin

Overview

Best Publications

• Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1

  Tsutomu Shimada;Carrie L. Hayes;Hiroshi Yamazaki;Shantu Amin

  1033
  Citations

• Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease

  Changtao Jiang;Changtao Jiang;Cen Xie;Fei Li;Limin Zhang

  649
  Citations

• Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction.

  Changtao Jiang;Cen Xie;Ying Lv;Jing Li

  569
  Citations

• Inhibition of tobacco-specific nitrosamine-induced lung tumorigenesis in A/J mice by green tea and its major polyphenol as antioxidants.

  Yong Xu;Chi-Tang Ho;Shantu G. Amin;Chi Han

  515
  Citations

• Induction of Lung and Exocrine Pancreas Tumors in F344 Rats by Tobacco-specific and Areca-derived N-Nitrosamines

  Abraham Rivenson;Dietrich Hoffmann;Bogdan Prokopczyk;Shantu Amin

  446
  Citations

• Autophagosomal Membrane Serves as Platform for Intracellular Death-inducing Signaling Complex (iDISC)-mediated Caspase-8 Activation and Apoptosis

  Megan M. Young;Yoshinori Takahashi;Osman Khan;Sungman Park

  442
  Citations

• NMR SOLUTION STRUCTURES OF STEREOISOMERIC COVALENT POLYCYCLIC AROMATIC CARCINOGEN-DNA ADDUCTS : PRINCIPLES, PATTERNS, AND DIVERSITY

  Nicholas E. Geacintov;Monique Cosman;Brian E. Hingerty;Shantu Amin

  439
  Citations

• Targeting of Lung Cancer Mutational Hotspots by Polycyclic Aromatic Hydrocarbons

  Leslie E. Smith;Mikhail F. Denissenko;Mikhail F. Denissenko;William P. Bennett;Haiying Li

  388
  Citations

• Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles.

  Troy D. Hubbard;Iain A. Murray;William H. Bisson;Tejas S. Lahoti

  373
  Citations

• The major lipid peroxidation product, trans- 4-hydroxy-2-nonenal, preferentially forms DNA adducts at codon 249 of human p53 gene, a unique mutational hotspot in hepatocellular carcinoma

  Wenwei Hu;Zhaohui Feng;Jamie Eveleigh;Ganesh Iyer

  355
  Citations

• The uremic toxin 3-indoxyl sulfate is a potent endogenous agonist for the human aryl hydrocarbon receptor.

  Jennifer C. Schroeder;Brett C. DiNatale;Iain A. Murray;Colin A. Flaveny

  343
  Citations

• Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA adduct formation and tumorigenicity in the lung of F344 rats by dietary phenethyl isothiocyanate.

  Mark A. Morse;Chung-Xiou Wang;Gary D. Stoner;Swapna Mandal

  293
  Citations

• Effects of aromatic isothiocyanates on tumorigenicity, O6-methylguanine formation, and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung.

  Mark A. Morse;Shantu G. Amin;Stephen S. Hecht;Fung Lung Chung

  284
  Citations

• Inhibitory effect of caffeic acid esters on azoxymethane-induced biochemical changes and aberrant crypt foci formation in rat colon

  Chinthalapally V. Rao;Dhimant Desai;Barbara Simi;Nalini Kulkarni

  262
  Citations

• trans-Lesion synthesis past bulky benzo[a]pyrene diol epoxide N2-dG and N6-dA lesions catalyzed by DNA bypass polymerases.

  Olga Rechkoblit;Yanbin Zhang;Dongyu Guo;Zhigang Wang

  228
  Citations

• Effects of indole-3-carbinol on lung tumorigenesis and DNA methylation induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and on the metabolism and disposition of NNK in A/J mice.

  Mark A. Morse;Susan D. LaGreca;Shantu G. Amin;Fung Lung Chung

  218
  Citations

• Inhibition of Benzo( a )pyrene-induced Lung Tumorigenesis in A/J Mice by Dietary N -Acetylcysteine Conjugates of Benzyl and Phenethyl Isothiocyanates during the Postinitiation Phase Is Associated with Activation of Mitogen-activated Protein Kinases and p53 Activity and Induction of Apoptosis

  Yang-Ming Yang;C Clifford Conaway;J W Chiao;Chung-Xiou Wang

  209
  Citations

• Sulforaphane inhibits prostate carcinogenesis and pulmonary metastasis in TRAMP mice in association with increased cytotoxicity of natural killer cells.

  Shivendra V. Singh;Renaud Warin;Dong Xiao;Anna A. Powolny

  207
  Citations

• STRUCTURE-ACTIVITY RELATIONSHIPS FOR INHIBITION OF 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE LUNG TUMORIGENESIS BY ARYLALKYL ISOTHIOCYANATES IN A /J MICE

  Mark A. Morse;Karin I. Eklind;Stephen S. Hecht;Kevin G. Jordan

  204
  Citations

• CD34 Expression by Hair Follicle Stem Cells Is Required for Skin Tumor Development in Mice

  Carol S. Trempus;Rebecca J. Morris;Matthew Ehinger;Amy Elmore

  193
  Citations