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Biology and Biochemistry

D-Index
146
Citations
79284
World Ranking
207
National Ranking
143

Research.com Recognitions

  • 2014 - Fellow of the American Academy of Arts and Sciences
  • 2009 - Member of the National Academy of Sciences

Overview

Dinshaw J. Patel is a researcher affiliated with Memorial Sloan Kettering Cancer Center in the United States. Their work primarily spans the fields of biochemistry, genetics, molecular biology, and medicine, with a strong focus on subfields such as molecular biology, immunology, epidemiology, infectious diseases, and plant science.

The scientist's research topics cover a range of areas related to molecular and genetic processes, including:

  • RNA and protein synthesis mechanisms
  • CRISPR and genetic engineering
  • DNA repair mechanisms
  • RNA modifications and cancer
  • Genomics and chromatin dynamics
  • Cytomegalovirus and herpesvirus research
  • RNA research and splicing

Dinshaw J. Patel's recent publications include the following significant papers:

  • N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation (2021) published in Cancer Cell
  • RNA-Puzzles Round IV: 3D structure predictions of four ribozymes and two aptamers (2020) published in RNA
  • Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases (2020) published in Nature
  • The Card1 nuclease provides defence during type III CRISPR immunity (2021) published in Nature
  • A phage-encoded anti-CRISPR enables complete evasion of type VI-A CRISPR-Cas immunity (2020) published in Science

The scientist has frequently collaborated with several researchers, including:

  • Wei Xie
  • Juncheng Wang
  • You Yu
  • Luciano A. Marraffini
  • Brian D. Strahl

Dinshaw J. Patel's work has been published extensively in certain journals and venues, such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Research
  • Proceedings of the National Academy of Sciences
  • Nature
  • Nature Communications

Among the honors received by the scientist are:

  • Fellow of the American Academy of Arts and Sciences (2014)
  • Member of the National Academy of Sciences (2009)

Best Publications

  • Adaptive recognition by nucleic acid aptamers.

    Thomas Hermann;Dinshaw J. Patel

  • How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers

    Sean D Taverna;Haitao Li;Alexander J Ruthenburg;C David Allis

  • Multivalent engagement of chromatin modifications by linked binding modules.

    Alexander J. Ruthenburg;Haitao Li;Dinshaw J. Patel;C. David Allis

  • Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase

    Pu Gao;Manuel Ascano;Yang Wu;Winfried Barchet

  • Human telomere, oncogenic promoter and 5′-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics

    Dinshaw J. Patel;Anh Tuân Phan;Vitaly Kuryavyi

  • A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

    Laurens Kruidenier;Chun-wa Chung;Zhongjun Cheng;John Liddle

  • Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF

    Haitao Li;Serge Ilin;Wooikoon Wang;Elizabeth M. Duncan

  • Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain.

    Jin-Biao Ma;Keqiong Ye;Dinshaw J. Patel

  • Structure of the Human Telomere in K+ Solution: An Intramolecular (3 + 1) G-Quadruplex Scaffold

    Kim Ngoc Luu;Anh Tuân Phan;Vitaly Kuryavyi;Laurent Lacroix

  • DNA methylation pathways and their crosstalk with histone methylation.

    Jiamu Du;Lianna M. Johnson;Steven E. Jacobsen;Dinshaw J. Patel

  • Cucumber mosaic virus-encoded 2b suppressor inhibits Arabidopsis Argonaute1 cleavage activity to counter plant defense

    Xiuren Zhang;Yu-Ren Yuan;Yi Pei;Shih-Shun Lin

  • Structural basis for 5′-end-specific recognition of guide RNA by the A. fulgidus Piwi protein

    Jin-Biao Ma;Yu-Ren Yuan;Gunter Meister;Yi Pei

  • Non-CG methylation patterns shape the epigenetic landscape in Arabidopsis.

    Hume Stroud;Truman Do;Jiamu Du;Xuehua Zhong

  • Structural Basis for Discriminative Regulation of Gene Expression by Adenine- and Guanine-Sensing mRNAs

    Alexander Serganov;Yu Ren Yuan;Olga Pikovskaya;Anna Polonskaia

  • Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex

    Yanli Wang;Stefan Juranek;Haitao Li;Gang Sheng

  • Dicer recognizes the 5′ end of RNA for efficient and accurate processing

    Jong-Eun Park;Inha Heo;Yuan Tian;Dhirendra K. Simanshu

  • Structure of the guide-strand-containing argonaute silencing complex

    Yanli Wang;Gang Sheng;Stefan Juranek;Thomas Tuschl

  • PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing.

    Quan Zhao;Quan Zhao;Gerhard Rank;Yuen T Tan;Haitao Li

  • Propeller-type parallel-stranded G-quadruplexes in the human c-myc promoter.

    Anh Tuân Phan;Yasha S. Modi;Dinshaw J. Patel

  • Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes.

    Yanli Wang;Stefan Juranek;Haitao Li;Gang Sheng

Frequent Co-Authors

Suse Broyde
Suse Broyde New York University
Nicholas E. Geacintov
Nicholas E. Geacintov New York University
Rhoderick E. Brown
Rhoderick E. Brown University of Minnesota
Thomas Tuschl
Thomas Tuschl Rockefeller University
Anh Tuân Phan
Anh Tuân Phan Nanyang Technological University
Roger A. Jones
Roger A. Jones Rutgers, The State University of New Jersey
Haitao Li
Haitao Li Tsinghua University
C. David Allis
C. David Allis Rockefeller University
Shantu Amin
Shantu Amin Pennsylvania State University
Xiaolian Gao
Xiaolian Gao University of Houston

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