D-Index & Metrics Best Publications
Molecular Biology
USA
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 120 Citations 129,503 334 World Ranking 146 National Ranking 95

Research.com Recognitions

Awards & Achievements

2023 - Research.com Molecular Biology in United States Leader Award

2009 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Human Genetics and Molecular Medicine

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • RNA

Thomas Tuschl mainly focuses on RNA, Genetics, RNA silencing, Gene silencing and Molecular biology. Thomas Tuschl works mostly in the field of Genetics, limiting it down to concerns involving Computational biology and, occasionally, PAR-CLIP, RNA-binding protein and Ribonucleoprotein. His RNA silencing study combines topics in areas such as Small interfering RNA, Non-coding RNA, RNA-induced transcriptional silencing and Trans-acting siRNA.

His Trans-acting siRNA research incorporates elements of RNA-induced silencing complex and Argonaute. Thomas Tuschl interconnects RIG-I, DNA-directed RNA interference, Transfection and Cell biology in the investigation of issues within Molecular biology. His microRNA research is multidisciplinary, incorporating elements of Regulation of gene expression, Three prime untranslated region, Genome and Gene expression.

His most cited work include:

  • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells (9207 citations)
  • Identification of novel genes coding for small expressed RNAs. (4128 citations)
  • RNA interference is mediated by 21- and 22-nucleotide RNAs (3478 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are microRNA, RNA, Molecular biology, Genetics and Cell biology. The study incorporates disciplines such as Cancer research, Gene silencing, Deep sequencing and Gene expression profiling in addition to microRNA. His work in Molecular biology addresses subjects such as Biochemistry, which are connected to disciplines such as Stereochemistry.

His study ties his expertise on Computational biology together with the subject of Genetics. His study in Cell biology is interdisciplinary in nature, drawing from both DNA-directed RNA interference, Messenger RNA and RNA splicing. His research investigates the connection between RNA silencing and topics such as Trans-acting siRNA that intersect with problems in Argonaute.

He most often published in these fields:

  • microRNA (33.54%)
  • RNA (30.72%)
  • Molecular biology (29.78%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cell biology (26.33%)
  • RNA (30.72%)
  • microRNA (33.54%)

In recent papers he was focusing on the following fields of study:

Thomas Tuschl mainly investigates Cell biology, RNA, microRNA, Molecular biology and Lupus nephritis. His Cell biology research is multidisciplinary, incorporating perspectives in IRF3, Viral infection, Translation, Gene silencing and Transcription. The subject of his RNA research is within the realm of Genetics.

His biological study spans a wide range of topics, including Cancer research, Gene expression profiling, Lung cancer, Induced pluripotent stem cell and Regulation of gene expression. His studies deal with areas such as Interferon, Internal ribosome entry site, Small molecule and Ribosomal binding site as well as Molecular biology. His study on Lupus nephritis also encompasses disciplines like

  • Cell which is related to area like Transcriptome, Extracellular matrix, Atopic dermatitis and Keratinocyte,
  • Systemic lupus erythematosus which is related to area like Molecular pathogenesis,
  • Kidney that intertwine with fields like Biopsy, Immunology and Pathology,
  • Oncology together with Cardiac allograft, Heart failure, Circulating mirnas, Heart transplantation and Gold standard.

Between 2015 and 2021, his most popular works were:

  • Characterizing Expression and Processing of Precursor and Mature Human tRNAs by Hydro-tRNAseq and PAR-CLIP (96 citations)
  • Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice. (93 citations)
  • Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice. (93 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

His main research concerns Cell biology, microRNA, Genetics, Biochemistry and Gene. He interconnects Translation, Gene silencing and RNA-binding protein in the investigation of issues within Cell biology. His microRNA study integrates concerns from other disciplines, such as Regulation of gene expression, Cancer research and Gene expression profiling.

His study in Genetics concentrates on Germline, PAR-CLIP, RNA, SOX2 and Reprogramming. His RNA study combines topics in areas such as DNA sequencing, Computational biology, Immunoprecipitation and Genomic library. As a part of the same scientific study, Thomas Tuschl usually deals with the Ribosome profiling, concentrating on Ribosomal binding site and frequently concerns with Molecular biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Sayda M. Elbashir;Jens Harborth;Winfried Lendeckel;Abdullah Yalcin.
Nature (2001)

13622 Citations

Identification of novel genes coding for small expressed RNAs.

Mariana Lagos-Quintana;Reinhard Rauhut;Winfried Lendeckel;Thomas Tuschl.
Science (2001)

6314 Citations

RNA interference is mediated by 21- and 22-nucleotide RNAs

Sayda M. Elbashir;Winfried Lendeckel;Thomas Tuschl.
Genes & Development (2001)

5381 Citations

Silencing of microRNAs in vivo with ‘antagomirs’

Jan Krützfeldt;Nikolaus Rajewsky;Ravi Braich;Kallanthottathil G. Rajeev.
Nature (2005)

4779 Citations

Human MicroRNA Targets

Bino John;Anton James Enright;Anton James Enright;Alexei Aravin;Thomas Tuschl.
PLOS Biology (2004)

4235 Citations

A mammalian microRNA expression atlas based on small RNA library sequencing.

Pablo Landgraf;Mirabela Rusu;Robert Sheridan;Alain Sewer;Alain Sewer.
Cell (2007)

4233 Citations

RNAi: Double-Stranded RNA Directs the ATP-Dependent Cleavage of mRNA at 21 to 23 Nucleotide Intervals

Phillip D. Zamore;Thomas Tuschl;Phillip A. Sharp;David P. Bartel.
Cell (2000)

4230 Citations

Identification of tissue-specific microRNAs from mouse

Mariana Lagos-Quintana;Reinhard Rauhut;Abdullah Yalcin;Jutta Meyer.
Current Biology (2002)

4125 Citations

A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA.

György Hutvágner;Juanita McLachlan;Amy E. Pasquinelli;Éva Bálint.
Science (2001)

3667 Citations

MicroRNA targets in Drosophila

Anton J Enright;Bino John;Ulrike Gaul;Thomas Tuschl.
Genome Biology (2003)

3400 Citations

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