D-Index & Metrics Best Publications
Research.com 2022 Best Female Scientist Award Badge
Genetics
USA
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Best female scientists D-index 143 Citations 100,160 486 World Ranking 130 National Ranking 84
Genetics D-index 137 Citations 92,923 419 World Ranking 123 National Ranking 67

Research.com Recognitions

Awards & Achievements

2023 - Research.com Genetics in United States Leader Award

2022 - Research.com Best Female Scientist Award

2020 - Fellow of John Simon Guggenheim Memorial Foundation

2020 - Nobel Prize for the development of a method for genome editing

2018 - NAS Award in Chemical Sciences, National Academy of Sciences (US) For co-inventing the technology for efficient site-specific genome engineering using CRISPR/Cas9 nucleases.

2017 - F.A. Cotton Medal for Excellence in Chemical Research, American Chemical Society (ACS)

2017 - Japan Prize for deciphering the molecular details of the type II bacterial immune system CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-Cas and the creation of the CRISPR-Cas9 genome editing system, a truly revolutionary technique in genetic engineering, far more economical and faster than those previously available.

2017 - Albany Medical Center Prize in Medicine and Biomedical Research

2016 - BBVA Foundation Frontiers of Knowledge Award

2016 - Fellow of the Royal Society, United Kingdom

2016 - Canada Gairdner International Award

2016 - Murray Goodman Memorial Prize, American Chemical Society (ACS)

2016 - Warren Alpert Foundation Prize For remarkable contributions to the understanding of the CRISPR bacterial defense system and the revolutionary discovery that it can be adapted for genome editing.

2015 - Breakthrough Prize in Life Sciences for harnessing an ancient mechanism of bacterial immunity into a powerful and general technology for editing genomes, with wide-ranging implications across biology and medicine.

2015 - Gruber Prize in Genetics

2014 - Fellow, National Academy of Inventors

2014 - Lurie Prize in Biomedical Sciences, Foundation for the National Institutes of Health

2014 - Dr. Paul Janssen Award for Biomedical Research, Johnson & Johnson for their work on a new method for precise and facile genomic editing.

2010 - Member of the National Academy of Medicine (NAM)

2008 - Fellow of the American Association for the Advancement of Science (AAAS)

2002 - Member of the National Academy of Sciences

2000 - National Science Foundation Alan T. Waterman Award Biochemistry

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • DNA
  • RNA

Jennifer A. Doudna mainly focuses on RNA, CRISPR, Genetics, Cas9 and Computational biology. Her RNA research includes elements of Base pair and Cell biology. Her research is interdisciplinary, bridging the disciplines of DNA and CRISPR.

Her Genetics study frequently draws connections to adjacent fields such as Protein structure. She is studying Protospacer adjacent motif, which is a component of Cas9. Her studies deal with areas such as Nucleic acid structure, Genome engineering, Genome, Function and Regulation of gene expression as well as Computational biology.

Her most cited work include:

  • A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. (9018 citations)
  • The new frontier of genome engineering with CRISPR-Cas9 (3361 citations)
  • The new frontier of genome engineering with CRISPR-Cas9 (3361 citations)

What are the main themes of her work throughout her whole career to date?

Her primary areas of investigation include RNA, CRISPR, Computational biology, Genetics and Cas9. Her RNA study combines topics from a wide range of disciplines, such as Base pair, Nucleic acid and Cell biology. Her research investigates the connection between CRISPR and topics such as DNA that intersect with problems in Acquired immune system and Biophysics.

The concepts of her Computational biology study are interwoven with issues in Genome engineering, Genome, Nuclease, DNA sequencing and Effector. Many of her studies on Genetics involve topics that are commonly interrelated, such as Protein structure. Jennifer A. Doudna specializes in Cas9, namely Protospacer adjacent motif.

She most often published in these fields:

  • RNA (49.63%)
  • CRISPR (40.71%)
  • Computational biology (39.03%)

What were the highlights of her more recent work (between 2018-2021)?

  • CRISPR (40.71%)
  • Computational biology (39.03%)
  • DNA (21.75%)

In recent papers she was focusing on the following fields of study:

Her main research concerns CRISPR, Computational biology, DNA, RNA and Genome editing. Jennifer A. Doudna has researched CRISPR in several fields, including Bacteriophage, Effector, Cell biology and Nucleic acid. Her Computational biology research incorporates elements of Cleavage, Genome, Cas9, Mobile genetic elements and Nuclease.

Her work in the fields of Cas9, such as Guide RNA, overlaps with other areas such as Streptococcus pyogenes. Her work focuses on many connections between DNA and other disciplines, such as Enzyme, that overlap with her field of interest in Bacteria. Her RNA study combines topics in areas such as Trans-activating crRNA, Severe acute respiratory syndrome coronavirus 2 and Virology.

Between 2018 and 2021, her most popular works were:

  • CasX enzymes comprise a distinct family of RNA-guided genome editors (172 citations)
  • The promise and challenge of therapeutic genome editing (163 citations)
  • Clades of huge phages from across Earth’s ecosystems (133 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

Jennifer A. Doudna mainly investigates CRISPR, Genome editing, DNA, Computational biology and Genome. Her CRISPR study which covers Cell biology that intersects with Subgenomic mRNA. Her research in DNA intersects with topics in Cas9, Guide RNA, RNA, Enzyme and Bacteria.

Her biological study spans a wide range of topics, including Plasmid, Mobile genetic elements, Base pair, Nucleic acid thermodynamics and Effector. Genetics covers Jennifer A. Doudna research in Genome. Her research in the fields of Inverted repeat overlaps with other disciplines such as Population.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.

Martin Jinek;Krzysztof Chylinski;Krzysztof Chylinski;Ines Fonfara;Michael Hauer.
Science (2012)

14198 Citations

The new frontier of genome engineering with CRISPR-Cas9

Jennifer A. Doudna;Jennifer A. Doudna;Emmanuelle Charpentier;Emmanuelle Charpentier.
Science (2014)

5344 Citations

Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression.

Lei S. Qi;Matthew H. Larson;Luke A. Gilbert;Jennifer A. Doudna.
Cell (2013)

4399 Citations

CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

Luke A. Gilbert;Matthew H. Larson;Leonardo Morsut;Zairan Liu.
Cell (2013)

3317 Citations

RNA-programmed genome editing in human cells

Martin Jinek;Alexandra East;Aaron Cheng;Steven Lin.
eLife (2013)

2336 Citations

RNA-guided genetic silencing systems in bacteria and archaea

Blake Wiedenheft;Samuel H. Sternberg;Jennifer A. Doudna.
Nature (2012)

2186 Citations

DNA interrogation by the CRISPR RNA-guided endonuclease Cas9

Samuel H. Sternberg;Sy Redding;Martin Jinek;Eric C. Greene.
Nature (2014)

2093 Citations

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity

Janice S. Chen;Enbo Ma;Lucas B. Harrington;Maria Da Costa.
Science (2018)

1749 Citations

Crystal Structure of a Group I Ribozyme Domain: Principles of RNA Packing

Jamie H. Cate;Anne R. Gooding;Anne R. Gooding;Elaine Podell;Elaine Podell;Kaihong Zhou.
Science (1996)

1673 Citations

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

Vikram Pattanayak;Steven Lin;John P Guilinger;Enbo Ma.
Nature Biotechnology (2013)

1581 Citations

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