D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 91 Citations 24,876 293 World Ranking 1134 National Ranking 486

Research.com Recognitions

Awards & Achievements

2005 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • DNA
  • Gene

His primary areas of study are RNA, Ribozyme, Biochemistry, Stereochemistry and Active site. His RNA research integrates issues from Crystallography, Biophysics and Tetrahymena, Cell biology. His study looks at the intersection of Tetrahymena and topics like Folding with Nucleic acid and Computational biology.

His Ribozyme research incorporates themes from Transfer RNA, RNA splicing and Bioinformatics. His work carried out in the field of Stereochemistry brings together such families of science as Reaction rate constant, Base pair, Binding site and Leaving group. His study in Active site is interdisciplinary in nature, drawing from both Guanosine, Phosphate, Nucleophile and Substrate.

His most cited work include:

  • Precision and functional specificity in mRNA decay (642 citations)
  • Genome-wide analysis of mRNA translation profiles in Saccharomyces cerevisiae. (611 citations)
  • Catalytic promiscuity and the evolution of new enzymatic activities (600 citations)

What are the main themes of his work throughout his whole career to date?

Daniel Herschlag mostly deals with RNA, Stereochemistry, Ribozyme, Active site and Biochemistry. His RNA research includes themes of Crystallography, Biophysics, Folding, Computational biology and Intron. In his research, Medicinal chemistry is intimately related to Reaction rate constant, which falls under the overarching field of Stereochemistry.

His Ribozyme study incorporates themes from Guanosine, Oligonucleotide and Tetrahymena. His studies in Active site integrate themes in fields like Isomerase, Enzyme catalysis and Hydrogen bond. His work investigates the relationship between Catalysis and topics such as Inorganic chemistry that intersect with problems in Ion.

He most often published in these fields:

  • RNA (34.23%)
  • Stereochemistry (30.63%)
  • Ribozyme (24.92%)

What were the highlights of his more recent work (between 2014-2021)?

  • RNA (34.23%)
  • Computational biology (9.01%)
  • Stereochemistry (30.63%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in RNA, Computational biology, Stereochemistry, Isomerase and Chemical physics. His Stereochemistry study combines topics in areas such as Molecular recognition, Ligand, Small molecule and Oligonucleotide. The various areas that Daniel Herschlag examines in his Isomerase study include Oxyanion hole and Active site.

The subject of his Active site research is within the realm of Biochemistry. His studies deal with areas such as Ion, Macromolecule, Molecule and Conformational ensembles as well as Chemical physics. In his study, Biophysics and Nuclear magnetic resonance spectroscopy is strongly linked to Tetrahymena, which falls under the umbrella field of Ribozyme.

Between 2014 and 2021, his most popular works were:

  • Visualizing the formation of an RNA folding intermediate through a fast highly modular secondary structure switch. (101 citations)
  • The roles of structural dynamics in the cellular functions of RNAs. (96 citations)
  • High-throughput analysis and protein engineering using microcapillary arrays. (60 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • DNA
  • Gene

Daniel Herschlag spends much of his time researching RNA, Computational biology, Nucleic acid structure, Folding and Chemical physics. His work carried out in the field of RNA brings together such families of science as Messenger RNA and Conformational ensembles. His Computational biology research is multidisciplinary, relying on both Enzyme catalysis, Site-directed mutagenesis, Function, Interaction network and Ribosome.

His biological study spans a wide range of topics, including Ion and Nanotechnology. His Chemical physics study also includes

  • Hydrogen bond together with Isomerase,
  • Molecule which intersects with area such as Electrostatics. His research in Oxyanion hole focuses on subjects like Stereochemistry, which are connected to Molecular recognition.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A single-molecule study of RNA catalysis and folding.

Xiaowei Zhuang;Laura E. Bartley;Hazen P. Babcock;Rick Russell.
Science (2000)

901 Citations

Catalytic promiscuity and the evolution of new enzymatic activities

Patrick J O'Brien;Daniel Herschlag.
Chemistry & Biology (1999)

888 Citations

Precision and functional specificity in mRNA decay

Yulei Wang;Chih Long Liu;John D. Storey;Robert J. Tibshirani.
Proceedings of the National Academy of Sciences of the United States of America (2002)

858 Citations

RNA chaperones and the RNA folding problem.

Daniel Herschlag.
Journal of Biological Chemistry (1995)

805 Citations

Genome-wide analysis of mRNA translation profiles in Saccharomyces cerevisiae.

Yoav Arava;Yulei Wang;John D. Storey;Chih Long Liu.
Proceedings of the National Academy of Sciences of the United States of America (2003)

765 Citations

Extensive Association of Functionally and Cytotopically Related mRNAs with Puf Family RNA-Binding Proteins in Yeast

André P Gerber;Daniel Herschlag;Patrick O Brown.
PLOS Biology (2004)

708 Citations

Diverse RNA-Binding Proteins Interact with Functionally Related Sets of RNAs, Suggesting an Extensive Regulatory System

Daniel J Hogan;Daniel P Riordan;André P Gerber;Daniel Herschlag.
PLOS Biology (2008)

594 Citations

Concordant regulation of translation and mRNA abundance for hundreds of targets of a human microRNA.

David G. Hendrickson;Daniel J. Hogan;Heather L. McCullough;Jason W. Myers.
PLOS Biology (2009)

478 Citations

Nanomechanical measurements of the sequence-dependent folding landscapes of single nucleic acid hairpins

Michael T. Woodside;William M. Behnke-Parks;Kevan Larizadeh;Kevin Travers.
Proceedings of the National Academy of Sciences of the United States of America (2006)

470 Citations

Direct measurement of the full, sequence-dependent folding landscape of a nucleic acid

Michael T. Woodside;Peter C. Anthony;William M. Behnke-Parks;Kevan Larizadeh.
Science (2006)

440 Citations

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