World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
60
Citations
11061
World Ranking
9852
National Ranking
2757

Biology and Biochemistry

D-Index
67
Citations
14969
World Ranking
8264
National Ranking
3737

Research.com Recognitions

  • 2009 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2001 - Fellow of Alfred P. Sloan Foundation

Overview

Philip C. Bevilacqua is affiliated with Pennsylvania State University in the United States and contributes extensively to the field of biochemistry, genetics, and molecular biology. Their research spans several subfields, including molecular biology, genetics, ecology, plant science, and materials chemistry. The primary scientific focus is on RNA-related mechanisms, including RNA and protein synthesis, RNA modifications and cancer, RNA research and splicing, as well as DNA and nucleic acid chemistry.

Their work has been published frequently in various scientific venues. Notable publication venues include bioRxiv (Cold Spring Harbor Laboratory) with 10 publications, RNA with 8 publications, Biochemistry with 5, Nucleic Acids Research with 3, and Methods in Enzymology with 2 publications.

Among the recent papers published by Philip C. Bevilacqua are:

  • RNA multimerization as an organizing force for liquid-liquid phase separation, 2021, RNA
  • Functional Roles of Chelated Magnesium Ions in RNA Folding and Function, 2021, Biochemistry
  • Phase-specific RNA accumulation and duplex thermodynamics in multiphase coacervate models for membraneless organelles, 2022, Nature Chemistry
  • Prebiotically-relevant low polyion multivalency can improve functionality of membraneless compartments, 2020, Nature Communications
  • RNA sequence and structure control assembly and function of RNA condensates, 2021, RNA

Frequent collaborators include McCauley O. Meyer, Christine D. Keating, Saehyun Choi, Sarah M. Assmann, and Elizabeth A. Jolley. These coauthors have appeared with Bevilacqua in multiple publications, reflecting ongoing scientific partnerships.

The main topics of their research encompass:

  • RNA and protein synthesis mechanisms
  • RNA modifications and cancer
  • RNA Research and Splicing
  • Genomics and Phylogenetic Studies
  • Bacterial Genetics and Biotechnology
  • DNA and Nucleic Acid Chemistry
  • Advanced biosensing and bioanalysis techniques

Philip C. Bevilacqua has received several recognitions, including being named a Fellow of the American Association for the Advancement of Science (AAAS) in 2009 and a Fellow of the Alfred P. Sloan Foundation in 2001.

Best Publications

  • In vivo genome-wide profiling of RNA secondary structure reveals novel regulatory features

    Yiliang Ding;Yin Tang;Chun Kit Kwok;Yu Zhang

  • Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation

    Bart R. Anderson;Hiromi Muramatsu;Subba R. Nallagatla;Philip C. Bevilacqua

  • General acid-base catalysis in the mechanism of a hepatitis delta virus ribozyme.

    Shu Ichi Nakano;Durga M. Chadalavada;Philip C. Bevilacqua

  • RNA catalysis through compartmentalization

    Christopher A. Strulson;Rosalynn C. Molden;Rosalynn C. Molden;Christine D. Keating;Philip C. Bevilacqua

  • The double-stranded-RNA-binding motif: interference and much more

    Bin Tian;Philip C. Bevilacqua;Amy Diegelman-Parente;Michael B. Mathews

  • Minor-Groove Recognition of Double-Stranded RNA by the Double-Stranded RNA-Binding Domain from the RNA-Activated Protein Kinase PKR†

    Philip C. Bevilacqua;Thomas R. Cech

  • Template-directed RNA polymerization and enhanced ribozyme catalysis inside membraneless compartments formed by coacervates

    Raghav R. Poudyal;Rebecca M. Guth-Metzler;Andrew J. Veenis;Erica A. Frankel;Erica A. Frankel

  • 5'-Triphosphate-Dependent Activation of PKR by RNAs with Short Stem-Loops

    Subba Rao Nallagatla;Jungwook Hwang;Rebecca Toroney;Xiaofeng Zheng;Xiaofeng Zheng

  • Bioreactor droplets from liposome-stabilized all-aqueous emulsions

    Daniel C. Dewey;Christopher A. Strulson;David N. Cacace;Philip C. Bevilacqua

  • Mechanistic considerations for general acid-base catalysis by RNA: Revisiting the mechanism of the hairpin ribozyme

    Philip C. Bevilacqua

  • Dynamics of ribozyme binding of substrate revealed by fluorescence-detected stopped-flow methods

    Philip C. Bevilacqua;Ryszard Kierzek;Kenneth A. Johnson;Douglas H. Turner

  • Genome-Wide Analysis of RNA Secondary Structure.

    Philip C. Bevilacqua;Laura E. Ritchey;Zhao Su;Sarah M. Assmann

  • Polyamine/Nucleotide Coacervates Provide Strong Compartmentalization of Mg2+, Nucleotides, and RNA

    Erica A. Frankel;Philip C. Bevilacqua;Christine D. Keating

  • Catalytic roles for proton transfer and protonation in ribozymes.

    Philip C. Bevilacqua;Trevor S. Brown;Shu Ichi Nakano;Rieko Yajima

  • Regulation of innate immunity through RNA structure and the protein kinase PKR

    Subba Rao Nallagatla;Rebecca Toroney;Philip C Bevilacqua

  • Nucleoside modifications modulate activation of the protein kinase PKR in an RNA structure-specific manner

    SubbaRao Nallagatla;Philip C Bevilacqua

  • Mechanistic characterization of the HDV genomic ribozyme: assessing the catalytic and structural contributions of divalent metal ions within a multichannel reaction mechanism.

    Shu-ichi Nakano;David J. Proctor;Philip C. Bevilacqua

  • Prebiotically-relevant low polyion multivalency can improve functionality of membraneless compartments.

    Fatma Pir Cakmak;Saehyun Choi;McCauley C.O. Meyer;Philip C. Bevilacqua

  • Bridging the gap between in vitro and in vivo RNA folding

    Kathleen A. Leamy;Sarah M. Assmann;David H. Mathews;Philip C. Bevilacqua

  • The RNA structurome: transcriptome-wide structure probing with next-generation sequencing

    Chun Kit Kwok;Yin Tang;Sarah M. Assmann;Philip C. Bevilacqua

  • Physical Principles and Extant Biology Reveal Roles for RNA-Containing Membraneless Compartments in Origins of Life Chemistry

    Raghav R. Poudyal;Fatma Pir Cakmak;Christine D. Keating;Philip C. Bevilacqua

  • A 1.9 Å Crystal Structure of the HDV Ribozyme Precleavage Suggests both Lewis Acid and General Acid Mechanisms Contribute to Phosphodiester Cleavage

    Jui Hui Chen;Rieko Yajima;Durga M. Chadalavada;Elaine Chase

Frequent Co-Authors

Sarah M. Assmann
Sarah M. Assmann Pennsylvania State University
Sharon Hammes-Schiffer
Sharon Hammes-Schiffer Yale University
Douglas H. Turner
Douglas H. Turner University of Rochester
Paul Babitzke
Paul Babitzke Pennsylvania State University
Christine D. Keating
Christine D. Keating Pennsylvania State University
Ryszard Kierzek
Ryszard Kierzek Polish Academy of Sciences
David H. Mathews
David H. Mathews University of Rochester Medical Center
Craig E. Cameron
Craig E. Cameron University of North Carolina at Chapel Hill
Thomas R. Cech
Thomas R. Cech University of Colorado Boulder
Martin Gruebele
Martin Gruebele University of Illinois at Urbana-Champaign

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