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Chemistry

D-Index
58
Citations
12740
World Ranking
10564
National Ranking
37

Overview

Ryszard Kierzek is affiliated with the Polish Academy of Sciences in Poland. Their research predominantly focuses on the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these broad areas, they specialize in Molecular Biology, Infectious Diseases, Epidemiology, Cancer Research, and Cardiology and Cardiovascular Medicine.

The main research topics covered by their work include RNA and protein synthesis mechanisms, RNA modifications and cancer, RNA research and splicing, SARS-CoV-2 and COVID-19 research, viral infections and immunology research, DNA and nucleic acid chemistry, and influenza virus research studies.

Key recent publications by Ryszard Kierzek feature the following:

  • Secondary structure prediction for RNA sequences including N6-methyladenosine, 2022, Nature Communications
  • RNA Secondary Structure as a First Step for Rational Design of the Oligonucleotides towards Inhibition of Influenza A Virus Replication, 2020, Pathogens
  • Identification and Structural Aspects of G-Quadruplex-Forming Sequences from the Influenza A Virus Genome, 2021, International Journal of Molecular Sciences
  • Prevalence of Anti-SARS-CoV-2 Antibodies in Poznań, Poland, after the First Wave of the COVID-19 Pandemic, 2021, Vaccines
  • Universal and strain specific structure features of segment 08 genomic RNA of influenza A virus-application of 4-thiouridine photocrosslinking, 2021, Journal of Biological Chemistry

Frequent collaborators in their research include:

  • Elżbieta Kierzek
  • David H. Mathews
  • Walter N. Moss
  • Jake M. Peterson
  • Paweł Zmora

The scientist has published repeatedly in venues such as:

  • Zenodo (CERN European Organization for Nuclear Research)
  • bioRxiv (Cold Spring Harbor Laboratory)
  • RNA
  • International Journal of Molecular Sciences
  • Journal of Biological Chemistry

Best Publications

  • Improved free-energy parameters for predictions of RNA duplex stability

    Susan M. Freier;Ryszard Kierzek;John A. Jaeger;Naoki Sugimoto

  • Thermodynamic parameters for an expanded nearest-neighbor model for formation of RNA duplexes with Watson - Crick base pairs

    Tianbing Xia;John SantaLucia;Mark E. Burkard;Ryszard Kierzek

  • Context Dependence of Hydrogen Bond Free Energy Revealed by Substitutions in an RNA Hairpin

    John SantaLucia;Ryszard Kierzek;Douglas H. Turner

  • The contribution of pseudouridine to stabilities and structure of RNAs

    Elzbieta Kierzek;Magdalena Malgowska;Jolanta Lisowiec;Douglas H. Turner

  • Nucleotide chemistry. 16. Amidine protecting groups for oligonucleotide synthesis

    Lincoln J. McBride;Ryszard. Kierzek;Serge L. Beaucage;Marvin H. Caruthers

  • The thermodynamic stability of RNA duplexes and hairpins containing N6‐alkyladenosines and 2‐methylthio‐N6‐alkyladenosines

    Elzbieta Kierzek;Ryszard Kierzek

  • Dynamics of ribozyme binding of substrate revealed by fluorescence-detected stopped-flow methods

    Philip C. Bevilacqua;Ryszard Kierzek;Kenneth A. Johnson;Douglas H. Turner

  • Laser temperature-jump, spectroscopic, and thermodynamic study of salt effects on duplex formation by dGCATGC.

    Alison P. Williams;Carl E. Longfellow;Susan M. Freier;Ryszard Kierzek

  • Thermodynamic and spectroscopic study of bulge loops in oligoribonucleotides.

    Carl E. Longfellow;Ryszard Kierzek;Douglas H. Turner

  • Thermodynamics of Single Mismatches in RNA Duplexes

    Ryszard Kierzek;Mark E. Burkard;Douglas H. Turner

  • Free energy increments for hydrogen bonds in nucleic acid base pairs

    Douglas H. Turner;Naoki Sugimoto;Ryszard Kierzek;Scott D. Dreiker

  • Stabilities of consecutive A·C, C·C, G·G, U·C, and U·U mismatches in RNA internal Loops: Evidence for stable hydrogen-bonded U·U and C·C+ pairs

    John SantaLucia;Ryszard Kierzek;Douglas H. Turner

  • Polymer-supported RNA synthesis and its application to test the nearest-neighbor model for duplex stability.

    Ryszard Kierzek;Marvin H. Caruthers;Carl E. Longfellow;David Swinton

  • Improved parameters for prediction of RNA structure

    D H Turner;N Sugimoto;J A Jaeger;C E Longfellow

  • Sequence dependence for the energetics of dangling ends and terminal base pairs in ribonucleic acid.

    Naoki Sugimoto;Ryszard Kierzek;Douglas H. Turner

  • Exploring the energy landscape of a small RNA hairpin.

    Hairong Ma;David J. Proctor;Elzbieta Kierzek;Ryszard Kierzek

  • Stability of XGCGCp, GCGCYp, and XGCGCYp helixes: an empirical estimate of the energetics of hydrogen bonds in nucleic acids.

    Susan M. Freier;Naoki Sugimoto;Alison Sinclair;Dirk Alkema

  • Effects of GA mismatches on the structure and thermodynamics of RNA internal loops

    John SantaLucia;Ryszard Kierzek;Douglas H. Turner

  • Nearest-neighbor parameters for G.U mismatches: [formula; see text] is destabilizing in the contexts [formula; see text] and [formula; see text] but stabilizing in [formula; see text].

    Liyan He;Ryszard Kierzek;John SantaLucia;Amy E. Walter

  • Microarrays for identifying binding sites and probing structure of RNAs

    Ryszard Kierzek;Douglas H. Turner;Elzbieta Kierzek

Frequent Co-Authors

Douglas H. Turner
Douglas H. Turner University of Rochester
Marvin H. Caruthers
Marvin H. Caruthers University of Colorado Boulder
Philip C. Bevilacqua
Philip C. Bevilacqua Pennsylvania State University
Naoki Sugimoto
Naoki Sugimoto Konan University
Wlodzimierz J. Krzyzosiak
Wlodzimierz J. Krzyzosiak Polish Academy of Sciences
Edward Darzynkiewicz
Edward Darzynkiewicz University of Warsaw
Eric M. Phizicky
Eric M. Phizicky University of Rochester
David H. Mathews
David H. Mathews University of Rochester Medical Center
Mariusz Jaskolski
Mariusz Jaskolski Adam Mickiewicz University in Poznań
Valérie Gabelica
Valérie Gabelica University of Bordeaux

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