World's Best Scientists 2026 revealed!
Anna Marie Pyle

Anna Marie Pyle

D-Index & Metrics

Genetics

D-Index
88
Citations
25438
World Ranking
1179
National Ranking
565

Anna Marie Pyle publication distribution in Genetics in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Genetics in 2026. The highlighted bar marks where Anna Marie Pyle sits on this spectrum.

45–54 publications: 6 scientists 55–64 publications: 10 scientists 65–74 publications: 35 scientists 75–84 publications: 84 scientists 85–94 publications: 102 scientists 95–104 publications: 151 scientists 105–114 publications: 175 scientists 115–124 publications: 203 scientists 125–134 publications: 217 scientists 135–144 publications: 205 scientists 145–154 publications: 193 scientists 155–164 publications: 188 scientists 165–174 publications: 170 scientists 175–184 publications: 178 scientists 185–194 publications: 164 scientists 195–204 publications: 173 scientists 205–214 publications: 159 scientists 215–224 publications: 134 scientists 225–234 publications: 143 scientists 235–244 publications: 105 scientists 245–254 publications: 114 scientists 255–264 publications: 92 scientists 265–274 publications: 88 scientists 275–284 publications: 87 scientists 285–294 publications: 80 scientists 295–304 publications: 62 scientists 305–314 publications: 75 scientists 315–324 publications: 67 scientists 325–334 publications: 60 scientists 335–344 publications: 52 scientists 345–354 publications: 40 scientists 355–364 publications: 48 scientists 365–374 publications: 47 scientists 375–384 publications: 46 scientists 385–394 publications: 31 scientists 395–404 publications: 27 scientists 405–414 publications: 40 scientists 415–424 publications: 30 scientists 425–434 publications: 43 scientists 435–444 publications: 29 scientists 445–454 publications: 14 scientists 455–464 publications: 28 scientists 465–474 publications: 21 scientists 475–484 publications: 21 scientists 485–494 publications: 22 scientists 495–504 publications: 17 scientists 505–514 publications: 12 scientists 515–524 publications: 11 scientists 525–534 publications: 8 scientists 535–544 publications: 8 scientists 545–554 publications: 14 scientists 555–564 publications: 4 scientists 565–574 publications: 11 scientists 575–584 publications: 5 scientists 585–594 publications: 11 scientists 595–604 publications: 12 scientists 605–614 publications: 7 scientists 615–624 publications: 6 scientists 625–634 publications: 10 scientists 635–644 publications: 9 scientists 645–654 publications: 10 scientists 655–664 publications: 6 scientists 665–674 publications: 6 scientists 675–684 publications: 6 scientists 685–694 publications: 4 scientists 695–702 publications: 6 scientists 703+ publications: 100 scientists
45 publications 703+

This scientist: 263 publications — 69th percentile

69% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 703 publications or more.

Anna Marie Pyle D-index placement in Genetics in 2026

The chart shows the D-index (discipline H-index) distribution of Genetics scientists ranked by Research.com in 2026. The highlighted bar marks where Anna Marie Pyle sits on this spectrum.

40–41 D-Index: 24 scientists 42–43 D-Index: 52 scientists 44–45 D-Index: 84 scientists 46–47 D-Index: 112 scientists 48–49 D-Index: 118 scientists 50–51 D-Index: 141 scientists 52–53 D-Index: 143 scientists 54–55 D-Index: 145 scientists 56–57 D-Index: 179 scientists 58–59 D-Index: 162 scientists 60–61 D-Index: 175 scientists 62–63 D-Index: 191 scientists 64–65 D-Index: 172 scientists 66–67 D-Index: 184 scientists 68–69 D-Index: 164 scientists 70–71 D-Index: 158 scientists 72–73 D-Index: 150 scientists 74–75 D-Index: 136 scientists 76–77 D-Index: 127 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 111 scientists 82–83 D-Index: 110 scientists 84–85 D-Index: 110 scientists 86–87 D-Index: 84 scientists 88–89 D-Index: 102 scientists 90–91 D-Index: 66 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 70 scientists 96–97 D-Index: 54 scientists 98–99 D-Index: 60 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 55 scientists 104–105 D-Index: 45 scientists 106–107 D-Index: 42 scientists 108–109 D-Index: 28 scientists 110–111 D-Index: 39 scientists 112–113 D-Index: 25 scientists 114–115 D-Index: 31 scientists 116–117 D-Index: 29 scientists 118–119 D-Index: 34 scientists 120–121 D-Index: 29 scientists 122–123 D-Index: 29 scientists 124–125 D-Index: 18 scientists 126–127 D-Index: 27 scientists 128–129 D-Index: 22 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 11 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 12 scientists 138–139 D-Index: 21 scientists 140–141 D-Index: 4 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 14 scientists 146–147 D-Index: 6 scientists 148–149 D-Index: 10 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 9 scientists 154–155 D-Index: 8 scientists 156–157 D-Index: 8 scientists 158–159 D-Index: 9 scientists 160+ D-Index: 96 scientists
40 D-Index 160+

This scientist: 88 D-Index — 74th percentile

74% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 160 D-Index or more.

Research.com Recognitions

  • 2007 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2005 - Fellow of the American Academy of Arts and Sciences

Overview

Anna Marie Pyle is affiliated with Yale University in the United States and has a substantial body of work within Biochemistry, Genetics, and Molecular Biology, with a focus on molecular biology. Their research spans topics including RNA and protein synthesis mechanisms, RNA modifications and cancer, RNA research and splicing, interferon and immune responses, immune response and inflammation, cancer-related molecular mechanisms research, and advanced biosensing and bioanalysis techniques.

The scientist has contributed frequently to several publication venues. These include bioRxiv (Cold Spring Harbor Laboratory), where they have published 12 times, Nature Communications with 6 publications, Journal of Molecular Biology also with 6, Nucleic Acids Research with 4, and Methods in enzymology on CD-ROM/Methods in enzymology with 4 publications.

Recent papers authored or co-authored by Anna Marie Pyle include:

  • Author Correction: Visualizing group II intron dynamics between the first and second steps of splicing, 2022, Nature Communications
  • US-align: universal structure alignments of proteins, nucleic acids, and macromolecular complexes, 2022, Nature Methods
  • Comprehensive in vivo secondary structure of the SARS-CoV-2 genome reveals novel regulatory motifs and mechanisms, 2021, Molecular Cell
  • De novo emergence of a remdesivir resistance mutation during treatment of persistent SARS-CoV-2 infection in an immunocompromised patient: a case report, 2022, Nature Communications
  • Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes, 2021, PLoS Biology

Their frequent co-authors are:

  • Olga Fedorova
  • Chengxin Zhang
  • Han Wan
  • Rafael de Cesaris Araujo Tavares
  • Wenshuai Wang

Anna Marie Pyle's research has been recognized with fellowships from major scientific organizations. They were named a Fellow of the American Association for the Advancement of Science (AAAS) in 2007 and a Fellow of the American Academy of Arts and Sciences in 2005.

Best Publications

  • Mixed-ligand complexes of ruthenium(II): factors governing binding to DNA

    A. M. Pyle;J. P. Rehmann;R. Meshoyrer;C. V. Kumar

  • mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties

    Dong Chul Kang;Rahul V. Gopalkrishnan;Rahul V. Gopalkrishnan;Qingping Wu;Qingping Wu;Eckhard Jankowsky

  • Ribozymes: a distinct class of metalloenzymes

    Anna Marie Pyle

  • Translocation and Unwinding Mechanisms of RNA and DNA Helicases

    Anna Marie Pyle

  • DNA photocleavage by phenanthrenequinone diimine complexes of rhodium(III): shape-selective recognition and reaction

    Ayesha Sitlani;Eric C. Long;Anna M. Pyle;Jacqueline K. Barton

  • Crystal structure of a self-spliced group II intron.

    Navtej Toor;Kevin S. Keating;Sean D. Taylor;Anna Marie Pyle;Anna Marie Pyle

  • Probing Nucleic Acids with Transition Metal Complexes

    Anna Marie Pyle;Jacqueline K. Barton

  • Metal ions in the structure and function of RNA.

    Anna Marie Pyle

  • Structural Insights into RNA Recognition by RIG-I

    Dahai Luo;Steve C. Ding;Adriana Vela;Andrew Kohlway

  • RNA translocation and unwinding mechanism of HCV NS3 helicase and its coordination by ATP

    Sophie Dumont;Wei Cheng;Victor Serebrov;Rudolf K. Beran

  • The Molecular Interactions That Stabilize RNA Tertiary Structure: RNA Motifs, Patterns, and Networks

    Samuel E. Butcher;Anna Marie Pyle;Anna Marie Pyle

  • Active Disruption of an RNA-Protein Interaction by a DExH/D RNA Helicase

    Eckhard Jankowsky;Christian H. Gross;Stewart Shuman;Anna Marie Pyle;Anna Marie Pyle

  • Alternative Roles for Metal Ions in Enzyme Catalysis and the Implications for Ribozyme Chemistry

    Roland K. O. Sigel;Anna Marie Pyle

  • HOTAIR Forms an Intricate and Modular Secondary Structure

    Srinivas Somarowthu;Michal Legiewicz;Isabel Chillón;Marco Marcia

  • Spring-Loaded Mechanism of DNA Unwinding by Hepatitis C Virus NS3 Helicase

    Sua Myong;Michael M. Bruno;Michael M. Bruno;Anna M. Pyle;Anna M. Pyle;Taekjip Ha

  • RNA backbone: consensus all-angle conformers and modular string nomenclature (an RNA Ontology Consortium contribution).

    Jane S. Richardson;Bohdan Schneider;Laura W. Murray;Gary J. Kapral

  • The hepatitis C viral NS3 protein is a processive DNA helicase with cofactor enhanced RNA unwinding.

    Phillip S. Pang;Eckhard Jankowsky;Paul J. Planet;Anna Marie Pyle;Anna Marie Pyle

  • Calculating the electrostatic properties of RNA provides new insights into molecular interactions and function

    Kevin Chin;Kim A. Sharp;Barry Honig;Anna Marie Pyle;Anna Marie Pyle

  • Temperature-dependent innate defense against the common cold virus limits viral replication at warm temperature in mouse airway cells

    Ellen F. Foxman;James A. Storer;Megan E. Fitzgerald;Bethany R. Wasik

  • The DExH protein NPH-II is a processive and directional motor for unwinding RNA.

    Eckhard Jankowsky;Christian H. Gross;Stewart Shuman;Anna Marie Pyle;Anna Marie Pyle

Frequent Co-Authors

Akiko Iwasaki
Akiko Iwasaki Yale University
Jacqueline K. Barton
Jacqueline K. Barton California Institute of Technology
Eckhard Jankowsky
Eckhard Jankowsky Case Western Reserve University
Roland K. O. Sigel
Roland K. O. Sigel University of Zurich
Brett D. Lindenbach
Brett D. Lindenbach Yale University
Craig B. Wilen
Craig B. Wilen Yale University
Thomas R. Cech
Thomas R. Cech University of Colorado Boulder
Tamar Schlick
Tamar Schlick New York University
Philip S. Perlman
Philip S. Perlman Howard Hughes Medical Institute
Samuel E. Butcher
Samuel E. Butcher University of Wisconsin–Madison

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