What is she best known for?
The fields of study she is best known for:
Her scientific interests lie mostly in RNA, Ribozyme, Helicase, Stereochemistry and RNA Helicase A.
Anna Marie Pyle has researched RNA in several fields, including Base pair and Cell biology.
The concepts of her Ribozyme study are interwoven with issues in Nucleic acid tertiary structure, Metal ions in aqueous solution, Group II intron and Intron.
Her work deals with themes such as Computational biology and Function, which intersect with Group II intron.
Her work carried out in the field of Helicase brings together such families of science as NS3 and DNA.
Within one scientific family, Anna Marie Pyle focuses on topics pertaining to Virology under RNA Helicase A, and may sometimes address concerns connected to Receptor.
Her most cited work include:
- Mixed-ligand complexes of ruthenium(II): factors governing binding to DNA (1153 citations)
- mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties (527 citations)
- Crystal structure of a self-spliced group II intron (370 citations)
What are the main themes of her work throughout her whole career to date?
Anna Marie Pyle mainly focuses on RNA, Group II intron, Intron, Genetics and Ribozyme.
Her RNA research includes elements of Computational biology and Cell biology.
Her Group II intron research is multidisciplinary, incorporating perspectives in Group I catalytic intron, Nucleotide, Spliceosome, Active site and Group II intron splicing.
She works mostly in the field of Intron, limiting it down to topics relating to RNA splicing and, in certain cases, Exon and Protein tertiary structure, as a part of the same area of interest.
Her Ribozyme study incorporates themes from Native state, Biophysics, Stereochemistry and Binding site.
Her work in Helicase covers topics such as NS3 which are related to areas like NS2-3 protease.
She most often published in these fields:
- RNA (105.88%)
- Group II intron (58.50%)
- Intron (52.61%)
What were the highlights of her more recent work (between 2017-2021)?
- RNA (105.88%)
- Computational biology (35.62%)
- RIG-I (19.61%)
In recent papers she was focusing on the following fields of study:
Anna Marie Pyle mainly investigates RNA, Computational biology, RIG-I, Nucleic acid structure and Innate immune system.
Her specific area of interest is RNA, where Anna Marie Pyle studies Group II intron.
Her Group II intron study combines topics in areas such as Reverse transcriptase and Intron.
Her RIG-I research is multidisciplinary, incorporating elements of Protein domain, Stimulation and Adenosine triphosphate.
Her research on Nucleic acid structure also deals with topics like
- Genome, which have a strong connection to Hepatitis C virus and Viral rna,
- Sequence, which have a strong connection to Conserved sequence.
As part of one scientific family, Anna Marie Pyle deals mainly with the area of Innate immune system, narrowing it down to issues related to the Interferon, and often Receptor, Gene, Cytoplasm, Duplex and Gating.
Between 2017 and 2021, her most popular works were:
- Single-cell longitudinal analysis of SARS-CoV-2 infection in human bronchial epithelial cells (53 citations)
- Therapeutically Active RIG-I Agonist Induces Immunogenic Tumor Cell Killing in Breast Cancers (45 citations)
- Therapeutically Active RIG-I Agonist Induces Immunogenic Tumor Cell Killing in Breast Cancers (45 citations)
In her most recent research, the most cited papers focused on:
The scientist’s investigation covers issues in RNA, Computational biology, Viral replication, Nucleic acid structure and Cell biology.
Her RNA research integrates issues from Base pair and Intron.
Her Computational biology research incorporates elements of Processivity, RNA-Directed DNA Polymerase, Reverse transcriptase, Retrotransposon and Group II intron.
She combines subjects such as Ribosomal RNA, Internal ribosome entry site, Ribosome, Protein biosynthesis and microRNA with her study of Viral replication.
Her studies in Nucleic acid structure integrate themes in fields like RNA virus, Genome, Translational frameshift and Pseudoknot.
Anna Marie Pyle works mostly in the field of Cell biology, limiting it down to topics relating to RIG-I and, in certain cases, Interferon.
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