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Biology and Biochemistry
France
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
116
Citations
49172
World Ranking
750
National Ranking
12

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in France Leader Award
  • 2001 - Member of Academia Europaea
  • 2001 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2000 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Biochemistry and Biophysics
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Eric Westhof is affiliated with the University of Strasbourg in France and has contributed extensively to the fields of Biochemistry, Genetics, and Molecular Biology. Their work primarily focuses on Molecular Biology with significant involvement in Infectious Diseases, Ecology, Insect Science, and Endocrinology.

The main research topics covered in their publications include:

  • RNA and protein synthesis mechanisms
  • RNA modifications and cancer
  • Genomics and Phylogenetic Studies
  • RNA Research and Splicing
  • Protein Structure and Dynamics
  • SARS-CoV-2 and COVID-19 Research
  • Bacteriophages and microbial interactions

Westhof has published numerous papers in a variety of scientific journals, with frequent venues of publication being:

  • RNA
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • Proteins Structure Function and Bioinformatics
  • Nature Communications

Notable recent papers include:

  • "RNA-Puzzles Round IV: 3D structure predictions of four ribozymes and two aptamers", 2020, RNA
  • "The viral protein NSP1 acts as a ribosome gatekeeper for shutting down host translation and fostering SARS-CoV-2 translation", 2020, RNA
  • "High-resolution silkworm pan-genome provides genetic insights into artificial selection and ecological adaptation", 2022, Nature Communications
  • "Assessment of three-dimensional RNA structure prediction in CASP15", 2023, Proteins Structure Function and Bioinformatics
  • "Advances in RNA 3D Structure Modeling Using Experimental Data", 2020, Frontiers in Genetics

Frequent co-authors collaborating with Westhof include:

  • Zhichao Miao
  • Maciej Antczak
  • Marta Szachniuk
  • Rhiju Das
  • Xiaoling Tong

Throughout their career, Westhof has been recognized with several memberships and honors such as:

  • Fellow of the American Association for the Advancement of Science (AAAS), 2001
  • Member of Academia Europaea, 2001
  • German National Academy of Sciences Leopoldina - Nationale Akademie der Wissenschaften, 2000, in Biochemistry and Biophysics
  • Member of the European Molecular Biology Organization (EMBO)

Best Publications

  • Genome evolution in yeasts

    Bernard Dujon;David Sherman;Gilles Fischer;Pascal Durrens

  • Halogen bonds in biological molecules

    Pascal Auffinger;Franklin A. Hays;Eric Westhof;P. Shing Ho

  • Modelling of the three-dimensional architecture of group I catalytic introns based on comparative sequence analysis.

    François Michel;Eric Westhof

  • Single Processing Center Models for Human Dicer and Bacterial RNase III

    Haidi Zhang;Fabrice A Kolb;Lukasz Jaskiewicz;Eric Westhof

  • Geometric nomenclature and classification of RNA base pairs.

    Neocles B. Leontis;Eric Westhof

  • The non‐Watson–Crick base pairs and their associated isostericity matrices

    Neocles B. Leontis;Jesse Stombaugh;Eric Westhof

  • A standard reference frame for the description of nucleic acid base-pair geometry

    Wilma K Olson;Manju Bansal;Stephen K Burley;Richard E Dickerson

  • HIERARCHY AND DYNAMICS OF RNA FOLDING

    Philippe Brion;Eric Westhof

  • Correlation between segmental mobility and the location of antigenic determinants in proteins

    E. Westhof;D. Altschuh;D. Moras;A. C. Bloomer

  • Crystallographic refinement of yeast aspartic acid transfer RNA.

    E. Westhof;P. Dumas;D. Moras

  • Sequence elements outside the hammerhead ribozyme catalytic core enable intracellular activity.

    Anastasia Khvorova;Aurélie Lescoute;Eric Westhof;Sumedha D Jayasena

  • Crystal Structure of Paromomycin Docked into the Eubacterial Ribosomal Decoding A Site

    Quentin Vicens;Eric Westhof

  • Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding

    Boris François;Rupert J. M. Russell;James B. Murray;Fareed Aboul-ela

  • The building blocks and motifs of RNA architecture.

    Neocles B Leontis;Aurelie Lescoute;Eric Westhof

  • Analysis of RNA motifs.

    Neocles B Leontis;Eric Westhof

  • New loop-loop tertiary interactions in self-splicing introns of subgroup IC and ID: a complete 3D model of the Tetrahymena thermophila ribozyme

    Valerie Lehnert;Luc Jaeger;François Michele;Eric Westhof

  • Topology of three-way junctions in folded RNAs.

    Aurélie Lescoute;Eric Westhof

  • The dynamic landscapes of RNA architecture.

    José Almeida Cruz;Eric Westhof

  • Biogenesis of Circular RNAs.

    Quentin Vicens;Eric Westhof

  • Water: an integral part of nucleic acid structure.

    Eric Westhof

Frequent Co-Authors

Neocles B. Leontis
Neocles B. Leontis Bowling Green State University
Chantal Ehresmann
Chantal Ehresmann Centre national de la recherche scientifique, CNRS
Bernard Ehresmann
Bernard Ehresmann Centre national de la recherche scientifique, CNRS
Pascale Romby
Pascale Romby Centre national de la recherche scientifique, CNRS
Dino Moras
Dino Moras Institute of Genetics and Molecular and Cellular Biology
Richard Giegé
Richard Giegé Centre national de la recherche scientifique, CNRS
Thomas Hermann
Thomas Hermann University of California, San Diego
Jean-Pierre Ebel
Jean-Pierre Ebel Centre national de la recherche scientifique, CNRS
Dinshaw J. Patel
Dinshaw J. Patel Memorial Sloan Kettering Cancer Center

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