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Shinya Kuroda

Shinya Kuroda

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
14449
World Ranking
13653
National Ranking
955

Overview

Shinya Kuroda is affiliated with the University of Tokyo in Japan and has an extensive research background in biochemistry, genetics, molecular biology, and medicine. Their work spans molecular biology, physiology, endocrinology, diabetes and metabolism, surgery, and cancer research, reflecting a broad interdisciplinary approach to biomedical science.

The main research topics covered in Kuroda's work include:

  • Diet and metabolism studies
  • Adipose Tissue and Metabolism
  • Bioinformatics and Genomic Networks
  • Diabetes Management and Research
  • Gene Regulatory Network Analysis
  • Metabolomics and Mass Spectrometry Studies
  • Microbial Metabolic Engineering and Bioproduction

Kuroda's recent published papers highlight a focus on glucose metabolism, obesity, and metabolic cycles involving liver and muscle tissues. Notable papers include:

  • "Fat Induces Glucose Metabolism in Nontransformed Liver Cells and Promotes Liver Tumorigenesis" (2021), published in Cancer Research
  • "Transomics analysis reveals allosteric and gene regulation axes for altered hepatic glucose-responsive metabolism in obesity" (2020), published in Science Signaling
  • "Trans-omic analysis reveals obesity-associated dysregulation of inter-organ metabolic cycles between the liver and skeletal muscle" (2021), published in iScience
  • "Dynamic 13C Flux Analysis Captures the Reorganization of Adipocyte Glucose Metabolism in Response to Insulin" (2020), published in iScience
  • "High-Performance Genetically Encoded Green Fluorescent Biosensors for Intracellular l-Lactate" (2024), published in ACS Central Science

The frequent co-authors in Kuroda's publications include Ken-ichi Hironaka, Satoshi Ohno, Tomoyoshi Soga, Toshiya Kokaji, and Keigo Morita. This group often collaborates on research projects involving metabolic regulation and biochemical signaling pathways.

Kuroda has published extensively in journals such as Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, bioRxiv, iScience, Science Signaling, and Scientific Reports. The distribution of publications across these venues suggests a strong engagement with both peer-reviewed journals and open access preprint platforms.

Best Publications

  • Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells.

    K. Kaibuchi;S. Kuroda;M. Amano

  • Rac1 and Cdc42 Capture Microtubules through IQGAP1 and CLIP-170

    Masaki Fukata;Takashi Watanabe;Jun Noritake;Masato Nakagawa

  • Role of IQGAP1, a Target of the Small GTPases Cdc42 and Rac1, in Regulation of E-Cadherin- Mediated Cell-Cell Adhesion

    Shinya Kuroda;Masaki Fukata;Masato Nakagawa;Katsuhiko Fujii

  • Prediction and validation of the distinct dynamics of transient and sustained ERK activation.

    Satoru Sasagawa;Yu-ichi Ozaki;Kazuhiro Fujita;Shinya Kuroda;Shinya Kuroda

  • Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction

    K.-I. Hirata;A. Kikuchi;T. Sasaki;S. Kuroda

  • Identification of IQGAP as a Putative Target for the Small GTPases, Cdc42 and Rac1

    Shinya Kuroda;Masaki Fukata;Kenta Kobayashi;Masato Nakafuku

  • Dynamics of the Ras/ERK MAPK Cascade as Monitored by Fluorescent Probes

    Aki Fujioka;Kenta Terai;Reina E. Itoh;Kazuhiro Aoki

  • Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI).

    K Kishi;T Sasaki;S Kuroda;T Itoh

  • Purification and characterization from bovine brain cytosol of a protein that inhibits the dissociation of GDP from and the subsequent binding of GTP to smg p25A, a ras p21-like GTP-binding protein.

    T Sasaki;A Kikuchi;S Araki;Y Hata

  • Cdc42 and Rac1 Regulate the Interaction of IQGAP1 with β-Catenin

    Masaki Fukata;Shinya Kuroda;Shinya Kuroda;Masato Nakagawa;Aie Kawajiri

  • Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue.

    Kentaro Ihara;Sachiko Muraguchi;Masato Kato;Toshiyuki Shimizu

  • p140Sra-1 (Specifically Rac1-associated Protein) Is a Novel Specific Target for Rac1 Small GTPase

    Kenta Kobayashi;Shinya Kuroda;Masaki Fukata;Masaki Fukata;Tomoko Nakamura

  • Regulation of cross-linking of actin filament by IQGAP1, a target for Cdc42.

    Masaki Fukata;Masaki Fukata;Shinya Kuroda;Katsuhiko Fujii;Tomoko Nakamura

  • Trans-Omics: How To Reconstruct Biochemical Networks Across Multiple ‘Omic’ Layers

    Katsuyuki Yugi;Katsuyuki Yugi;Hiroyuki Kubota;Atsushi Hatano;Shinya Kuroda

  • Identification of AF-6 and Canoe as Putative Targets for Ras

    Masamitsu Kuriyama;Naozumi Harada;Shinya Kuroda;Takaharu Yamamoto

  • Involvement of Rho p21 small GTP-binding protein and its regulator in the HGF-induced cell motility.

    K Takaishi;T Sasaki;M Kato;W Yamochi

  • Regulation of cadherin-mediated cell–cell adhesion by the Rho family GTPases

    Kozo Kaibuchi;Shinya Kuroda;Masaki Fukata;Masato Nakagawa

  • Involvement of rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI) in cell motility.

    K Takaishi;A Kikuchi;S Kuroda;K Kotani

  • A mass conserved reaction-diffusion system captures properties of cell polarity.

    Mikiya Otsuji;Shuji Ishihara;Carl Co;Kozo Kaibuchi

  • Mesenchymal-epithelial transition during somitic segmentation is regulated by differential roles of Cdc42 and Rac1.

    Yukiko Nakaya;Shinya Kuroda;Yuji T. Katagiri;Kozo Kaibuchi

Frequent Co-Authors

Kozo Kaibuchi
Kozo Kaibuchi Nagoya University
Masaki Fukata
Masaki Fukata The Graduate University for Advanced Studies, SOKENDAI
Yoshimi Takai
Yoshimi Takai Kobe University
Tomoyoshi Soga
Tomoyoshi Soga Keio University
Yutaka Suzuki
Yutaka Suzuki University of Tokyo
Akira Kikuchi
Akira Kikuchi Osaka University
Keiichi I. Nakayama
Keiichi I. Nakayama Institute of Science Tokyo
Masato Nakagawa
Masato Nakagawa Kyoto University
Toshio Hakoshima
Toshio Hakoshima Nara Institute of Science and Technology
Yoshiharu Matsuura
Yoshiharu Matsuura Osaka University

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