H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 57 Citations 24,249 90 World Ranking 6720 National Ranking 466

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Phosphorylation

His primary scientific interests are in Rho-associated protein kinase, Cell biology, Myosin light-chain kinase, Molecular biology and Myosin. His Rho-associated protein kinase research incorporates themes from MAP kinase kinase kinase and Mitogen-activated protein kinase kinase. He combines topics linked to Lysophosphatidic acid with his work on Cell biology.

He is interested in Myosin-light-chain phosphatase, which is a field of Myosin light-chain kinase. His Molecular biology research is multidisciplinary, incorporating perspectives in RHOA and Protein kinase A. His Myosin phosphatase activity study, which is part of a larger body of work in Myosin, is frequently linked to Smooth muscle contraction, bridging the gap between disciplines.

His most cited work include:

  • Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase) (2500 citations)
  • Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase). (1726 citations)
  • Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase. (1005 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Cell biology, Rho-associated protein kinase, Phosphorylation, Kinase and Protein kinase A. As a part of the same scientific family, Mutsuki Amano mostly works in the field of Cell biology, focusing on Neurite and, on occasion, Cellular differentiation and Axon. He has included themes like Molecular biology, Myosin light-chain kinase, Small GTPase and Focal adhesion in his Rho-associated protein kinase study.

His Myosin light-chain kinase study improves the overall literature in Myosin. The Myosin phosphatase activity research Mutsuki Amano does as part of his general Myosin study is frequently linked to other disciplines of science, such as Myosin ATPase, therefore creating a link between diverse domains of science. His research integrates issues of Proteomics and Phosphoprotein in his study of Kinase.

He most often published in these fields:

  • Cell biology (64.15%)
  • Rho-associated protein kinase (50.00%)
  • Phosphorylation (32.08%)

What were the highlights of his more recent work (between 2017-2021)?

  • Cell biology (64.15%)
  • Phosphorylation (32.08%)
  • Kinase (27.36%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Cell biology, Phosphorylation, Kinase, MAPK/ERK pathway and Medium spiny neuron. His Cell biology research incorporates elements of Neurite, Dopamine and Transcription factor. His Phosphorylation research focuses on Protein phosphorylation in particular.

His research investigates the link between Kinase and topics such as Signal transduction that cross with problems in Phosphorylation sites, Intrinsically disordered proteins, Phosphoprotein and Neural development. The study incorporates disciplines such as Dopamine receptor, Dopaminergic and Related gene in addition to MAPK/ERK pathway. His study in Medium spiny neuron is interdisciplinary in nature, drawing from both Rap1 and CREB.

Between 2017 and 2021, his most popular works were:

  • Pathological Progression Induced by the Frontotemporal Dementia-Associated R406W Tau Mutation in Patient-Derived iPSCs (16 citations)
  • Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology. (11 citations)
  • Phosphorylation of Npas4 by MAPK Regulates Reward-Related Gene Expression and Behaviors. (9 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Phosphorylation

Mutsuki Amano focuses on Cell biology, Medium spiny neuron, Missense mutation, Cancer research and Tau protein. In his articles, he combines various disciplines, including Cell biology and Eticlopride. He combines subjects such as Adenosine, CREB, Cyclic AMP Response Element-Binding Protein and MAPK/ERK pathway with his study of Medium spiny neuron.

His research in Missense mutation intersects with topics in Calpain and Mutant.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

Kazushi Kimura;Masaaki Ito;Mutsuki Amano;Kazuyasu Chihara.
Science (1996)

3424 Citations

Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase).

Mutsuki Amano;Masaaki Ito;Kazushi Kimura;Yuko Fukata.
Journal of Biological Chemistry (1996)

2356 Citations

Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho

T. Matsui;M. Amano;T. Yamamoto;K. Chihara.
The EMBO Journal (1996)

1293 Citations

Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase.

Mutsuki Amano;Kazuyasu Chihara;Kazushi Kimura;Yuko Fukata.
Science (1997)

1290 Citations

Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells.

K. Kaibuchi;S. Kuroda;M. Amano.
Annual Review of Biochemistry (1999)

1279 Citations

Rho-Kinase Phosphorylates COOH-terminal Threonines of Ezrin/Radixin/Moesin (ERM) Proteins and Regulates Their Head-to-Tail Association

Takeshi Matsui;Masato Maeda;Yoshinori Doi;Shigenobu Yonemura.
Journal of Cell Biology (1998)

1131 Citations

Rho–Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells

Yuko Fukata;Kozo Kaibuchi;Mutsuki Amano.
Trends in Pharmacological Sciences (2001)

1042 Citations

Rho‐kinase/ROCK: A key regulator of the cytoskeleton and cell polarity

Mutsuki Amano;Masanori Nakayama;Kozo Kaibuchi.
Cytoskeleton (2010)

887 Citations

Rho-associated Kinase Directly Induces Smooth Muscle Contraction through Myosin Light Chain Phosphorylation

Yasuko Kureishi;Sei Kobayashi;Mutsuki Amano;Kazushi Kimura.
Journal of Biological Chemistry (1997)

825 Citations

Regulation and functions of Rho-associated kinase.

Mutsuki Amano;Yuko Fukata;Kozo Kaibuchi;Kozo Kaibuchi.
Experimental Cell Research (2000)

700 Citations

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