World's Best Scientists 2026 revealed!
David J. Hartshorne

David J. Hartshorne

D-Index & Metrics

Chemistry

D-Index
70
Citations
17013
World Ranking
5869
National Ranking
1798

Biology and Biochemistry

D-Index
78
Citations
20625
World Ranking
4569
National Ranking
2223

Overview

David J. Hartshorne is affiliated with the University of Arizona in the United States. Their recent research contributions include a publication in 2024 titled Correction: New Isoform of Cardiac Myosin Light Chain Kinase and the Role of Cardiac Myosin Phosphorylation in α1-Adrenoceptor Mediated Inotropic Response, which appeared in the journal PLoS ONE.

Their work involves collaboration with several co-authors, including:

  • Masaya Taniguchi
  • Ryuji Okamoto
  • Masaaki Ito
  • Itaru Goto
  • Satoshi Fujita

David J. Hartshorne's research has been published in venues such as:

  • PLoS ONE

While specific fields of study or main research topics are not listed, the recent publication indicates involvement in cardiac physiology, especially related to cardiac myosin light chain kinase and mechanisms mediating cardiac muscle contraction.

Best Publications

  • Calyculin A and okadaic acid: inhibitors of protein phosphatase activity

    H. Ishihara;B.L. Martin;D.L. Brautigan;H. Karaki

  • Distinct roles of ROCK (Rho-kinase) and MLCK in spatial regulation of MLC phosphorylation for assembly of stress fibers and focal adhesions in 3T3 fibroblasts.

    Go Totsukawa;Yoshihiko Yamakita;Shigeko Yamashiro;David J. Hartshorne

  • Inhibitory Phosphorylation Site for Rho-associated Kinase on Smooth Muscle Myosin Phosphatase

    Jianhua Feng;Masaaki Ito;Kazuhito Ichikawa;Naoki Isaka

  • Modulator protein as a component of the myosin light chain kinase from chicken gizzard.

    Renata Dabrowska;James M. F. Sherry;Debra K. Aromatorio;David J. Hartshorne

  • Distinct roles of MLCK and ROCK in the regulation of membrane protrusions and focal adhesion dynamics during cell migration of fibroblasts

    Go Totsukawa;Yue Wu;Yasuharu Sasaki;David J. Hartshorne

  • Myosin phosphatase: structure, regulation and function.

    Masaaki Ito;Takeshi Nakano;Ferenc Erdodi;David J. Hartshorne

  • Myosin light chain phosphatase: subunit composition, interactions and regulation.

    David J. Hartshorne;Masaaki Ito;Ferenc Erdödi

  • Activation of RhoA and Inhibition of Myosin Phosphatase as Important Components in Hypertension in Vascular Smooth Muscle

    Tetsuya Seko;Masaaki Ito;Yasuko Kureishi;Ryuji Okamoto

  • Hepatocyte deformation induced by cyanobacterial toxins reflects inhibition of protein phosphatases.

    J. E. Eriksson;D. Toivola;J. A. O. Meriluoto;H. Karaki

  • Rho-associated Kinase of Chicken Gizzard Smooth Muscle

    Jianhua Feng;Masaaki Ito;Yasuko Kureishi;Kazuhito Ichikawa

  • Characterization of the myosin-binding subunit of smooth muscle myosin phosphatase.

    H Shimizu;M Ito;M Miyahara;K Ichikawa

  • Phosphorylation of smooth muscle myosin at two distinct sites by myosin light chain kinase.

    Unknown

  • Roles of calcium and phosphorylation in the regulation of the activity of gizzard myosin.

    James M. F. Sherry;Alicja Gorecka;Mark O. Aksoy;Renata Dabrowska

  • Phosphorylation of CPI-17, an inhibitory phosphoprotein of smooth muscle myosin phosphatase, by Rho-kinase

    Mutsumi Koyama;Masaaki Ito;Jianhua Feng;Tetsuya Seko

  • Smooth muscle myosin light chain kinase.

    Michael P. Walsh;Susan Hinkins;Renata Dabrowska;David J. Hartshorne

  • Smooth Muscle Phosphatase Is Regulated in Vivo by Exclusion of Phosphorylation of Threonine 696 of MYPT1 by Phosphorylation of Serine 695 in Response to Cyclic Nucleotides

    Anne A. Wooldridge;Justin A. MacDonald;Ferenc Erdodi;Chaoyu Ma

  • Phosphorylation of the Large Subunit of Myosin Phosphatase and Inhibition of Phosphatase Activity

    Kazuhito Ichikawa;Masaaki Ito;David J. Hartshorne

  • Role of protein phosphatase type 1 in contractile functions: myosin phosphatase.

    David J. Hartshorne;Masaaki Ito;Ferenc Erdödi

  • Identification of the endogenous smooth muscle myosin phosphatase-associated kinase

    Justin A. MacDonald;Meredith A. Borman;Andrea Murányi;Avril V. Somlyo

  • Myosin phosphatase target subunit: Many roles in cell function

    Fumio Matsumura;David J. Hartshorne

  • Inhibition of Rho-associated kinase blocks agonist-induced Ca2+ sensitization of myosin phosphorylation and force in guinea-pig ileum

    Karl Swärd;Karl Dreja;Marija Susnjar;Per Hellstrand

Frequent Co-Authors

Masaaki Ito
Masaaki Ito Mie University
Shugo Watabe
Shugo Watabe Kitasato University
Michael P. Walsh
Michael P. Walsh University of Calgary
Pál Gergely
Pál Gergely University of Debrecen
Kozo Kaibuchi
Kozo Kaibuchi Nagoya University
Fumio Matsumura
Fumio Matsumura Rutgers, The State University of New Jersey
Timothy A. J. Haystead
Timothy A. J. Haystead Duke University
Ivan Rayment
Ivan Rayment University of Wisconsin–Madison
Mutsuki Amano
Mutsuki Amano Nagoya University
Nobuhiro Fusetani
Nobuhiro Fusetani Waseda University

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Best Scientists Citing David J. Hartshorne