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Biology and Biochemistry

D-Index
95
Citations
28468
World Ranking
1933
National Ranking
1059

Overview

Robert S. Adelstein is affiliated with the National Institutes of Health in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with a particular focus on cellular and molecular mechanisms.

Adelstein's recent publications cover a variety of topics related to cytoskeletal dynamics, cell migration, gene targeting, and cardiac repair. Notable papers include:

  • Nonmuscle myosin 2 regulates cortical stability during sprouting angiogenesis, 2020, Molecular Biology of the Cell
  • Mutations in non-muscle myosin 2A disrupt the actomyosin cytoskeleton in Sertoli cells and cause male infertility, 2020, Developmental Biology
  • PAK3 controls the tangential to radial migration switch of cortical interneurons by coordinating changes in cell shape and polarity, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Investigation of the molecular biology underlying the pronounced high gene targeting frequency at the Myh9 gene locus in mouse embryonic stem cells, 2020, PLoS ONE
  • Abstract We020: Myh9 plays a vital role in cardiac myofibroblast differentiation and is indispensable for cardiac repair after myocardial infarction, 2024, Circulation Research

The coauthors with whom Adelstein has frequently collaborated include:

  • Xuefei Ma
  • Derek C. Sung
  • Mohsin Ahmad
  • Connie B. Lerma Cervantes
  • Yingfan Zhang

Adelstein has contributed to various publication venues, with multiple papers appearing in:

  • Developmental Biology
  • Molecular Biology of the Cell
  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS ONE
  • Circulation Research

The main fields of study for Adelstein's work are:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broader disciplines, their research subfields include:

  • Molecular Biology
  • Cardiology and Cardiovascular Medicine
  • Reproductive Medicine
  • Rheumatology
  • Genetics

The primary research topics addressed in Adelstein's studies encompass:

  • Renal and related cancers
  • Sperm and Testicular Function
  • Urologic and reproductive health conditions
  • Angiogenesis and VEGF in Cancer
  • Connective tissue disorders research
  • Electrospun Nanofibers in Biomedical Applications
  • Neurogenesis and neuroplasticity mechanisms

Best Publications

  • Non-muscle myosin II takes centre stage in cell adhesion and migration.

    Miguel Vicente-Manzanares;Xuefei Ma;Robert S. Adelstein;Alan Rick Horwitz

  • Myosin IIA regulates cell motility and actomyosin–microtubule crosstalk

    Sharona Even-Ram;Andrew D. Doyle;Mary Anne Conti;Kazue Matsumoto

  • Phosphorylation of platelet myosin increases actin-activated myosin ATPase activity.

    Robert S. Adelstein;Mary Anne Conti

  • Complete Amino-Acid Sequence of Actin of Rabbit Skeletal Muscle

    Marshall Elzinga;John H. Collins;W. Michael Kuehl;Robert S. Adelstein

  • Phosphorylation of smooth muscle myosin light chain kinase by the catalytic subunit of adenosine 3': 5'-monophosphate-dependent protein kinase.

    Robert S. Adelstein;Mary Anne Conti;David R. Hathaway;Claude B. Klee

  • Human platelet myosin light chain kinase requires the calcium-binding protein calmodulin for activity.

    David R. Hathaway;Robert S. Adelstein

  • Identification of Neuronal Nuclei (NeuN) as Fox-3, a New Member of the Fox-1 Gene Family of Splicing Factors

    Kee K. Kim;Robert S. Adelstein;Sachiyo Kawamoto

  • Nonmuscle myosin II moves in new directions

    Mary Anne Conti;Robert S. Adelstein

  • Nonmuscle myosin II-B is required for normal development of the mouse heart

    Antonella N. Tullio;Domenico Accili;Victor J. Ferrans;Zu-Xi Yu

  • Identification and Characterization of Nonmuscle Myosin II-C, a New Member of the Myosin II Family

    Eliahu Golomb;Eliahu Golomb;Xuefei Ma;Siddhartha S. Jana;Yvette A. Preston

  • Effect of phosphorylation of smooth muscle myosin on actin activation and Ca2+ regulation.

    Samuel Chacko;Mary Anne Conti;Robert S. Adelstein

  • Defects in cell adhesion and the visceral endoderm following ablation of nonmuscle myosin heavy chain II-A in mice.

    Mary Anne Conti;Sharona Even-Ram;Chengyu Liu;Kenneth M. Yamada

  • Basic mechanism of three-dimensional collagen fibre transport by fibroblasts

    Adam S. Meshel;Qize Wei;Robert S. Adelstein;Michael P. Sheetz

  • Human nonmuscle myosin heavy chains are encoded by two genes located on different chromosomes.

    M Simons;M Wang;O W McBride;S Kawamoto

  • Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens.

    Michael Smutny;Hayley L. Cox;Joanne M. Leerberg;Eva M. Kovacs

  • Differential localization of myosin-II isozymes in human cultured cells and blood cells.

    Pamela Maupin;Carrie L. Phillips;Robert S. Adelstein;Thomas D. Pollard

  • Phorbol ester-induced activation of human platelets is associated with protein kinase C phosphorylation of myosin light chains

    Michiko Naka;Masakatsu Nishikawa;Robert S. Adelstein;Hiroyoshi Hidaka

  • Protein kinase C modulates in vitro phosphorylation of the smooth muscle heavy meromyosin by myosin light chain kinase.

    M Nishikawa;J R Sellers;R S Adelstein;H Hidaka

  • Myosin IIB is required for growth cone motility.

    Paul C. Bridgman;Sonya Dave;Clara F. Asnes;Antonella N. Tullio

  • Phosphorylation of Smooth Muscle Myosin Light Chain Kinase by the Catalytic Subunit of Adenosine 3': 5'-Monophosphate-dependent

    Robert S. Adelstein;Mary Anne Conti;R David;Claude B. Klee

Frequent Co-Authors

James R. Sellers
James R. Sellers National Institutes of Health
Claude B. Klee
Claude B. Klee National Institutes of Health
Andrei I. Ivanov
Andrei I. Ivanov Cleveland Clinic
Kazuyo Takeda
Kazuyo Takeda US Food and Drug Administration
Michael A. Beaven
Michael A. Beaven National Institutes of Health
Thomas D. Pollard
Thomas D. Pollard Yale University
Hiroyoshi Hidaka
Hiroyoshi Hidaka D. Western Therapeutics Institute (Japan)
Bechara Kachar
Bechara Kachar National Institutes of Health
Charles A. Parkos
Charles A. Parkos University of Michigan–Ann Arbor
Ryuichi Nishinakamura
Ryuichi Nishinakamura Kumamoto University

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