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Biology and Biochemistry
Japan
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
92
Citations
36264
World Ranking
2185
National Ranking
128

Hiroyoshi Hidaka publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Hiroyoshi Hidaka sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 773 publications — 99th percentile

99% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Hiroyoshi Hidaka D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Hiroyoshi Hidaka sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 92 D-Index — 89th percentile

89% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Hiroyoshi Hidaka is affiliated with the D. Western Therapeutics Institute in Japan. Their research primarily focuses on medical fields with a specific concentration on cardiology, cardiovascular medicine, pulmonary and respiratory medicine, ophthalmology, radiology, nuclear medicine, imaging, and public health.

The scientist's work spans several subfields, reflecting an interdisciplinary approach to medicine. Key areas of study include:

  • Cardiology and Cardiovascular Medicine
  • Pulmonary and Respiratory Medicine
  • Ophthalmology
  • Radiology, Nuclear Medicine and Imaging
  • Public Health, Environmental and Occupational Health

The main topics covered in their research demonstrate a particular interest in conditions related to cardiovascular and ocular health. These topics include:

  • Pulmonary Hypertension Research and Treatments
  • Cardiomyopathy and Myosin Studies
  • Renin-Angiotensin System Studies
  • Glaucoma and Retinal Disorders
  • Corneal Surgery and Disorders
  • Ocular Surface and Contact Lens

Hidaka has contributed to scientific literature through studies published in journals such as Cells and Ophthalmology Glaucoma. Notable recent papers include:

  • The Isoquinoline-Sulfonamide Compound H-1337 Attenuates SU5416/Hypoxia-Induced Pulmonary Arterial Hypertension in Rats, 2021, Cells
  • Phase Ⅰ/Ⅱ, Double-Masked, Randomized, Vehicle-Controlled Study of H-1337 Ophthalmic Solution for Glaucoma and Ocular Hypertension, 2022, Ophthalmology Glaucoma

Collaborations appear in their research, working frequently with co-authors who have contributed to multiple publications alongside them. These frequent collaborators include:

  • Yoko Yoshida
  • Kengo Sumi
  • Hiroki Shoji
  • Takayuki Jujo
  • Akira Naito

Best Publications

  • Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C.

    Hiroyoshi Hidaka;Masaki Inagaki;Sachiyo Kawamoto;Yasuharu Sasaki

  • Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells.

    Takashi Chijiwa;Atsushi Mishima;Masatoshi Hagiwara;Mamoru Sano

  • KN-62, 1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazi ne, a specific inhibitor of Ca2+/calmodulin-dependent protein kinase II

    Hiroshi Tokumitsu;Takashi Chijiwa;Masatoshi Hagiwara;Akihiro Mizutani

  • N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation

    Hiroyoshi Hidaka;Yasuharu Sasaki;Toshio Tanaka;Toyoshi Endo

  • Selective inhibition of catalytic activity of smooth muscle myosin light chain kinase.

    M Saitoh;T Ishikawa;S Matsushima;M Naka

  • 1-(5-isoquinol inesulfonyl)-2-methylpiperazine (H-7) is a selective inhibitor of protein kinase c in rabbit platelets

    Sachiyo Kawamoto;Hiroyoshi Hidaka

  • The newly synthesized selective Ca2+calmodulin dependent protein kinase II inhibitor KN-93 reduces dopamine contents in PC12h cells

    Mariko Sumi;Kazutoshi Kiuchi;Tomohiko Ishikawa;Akira Ishii

  • Effect of AT877 on cerebral vasospasm after aneurysmal subarachnoid hemorrhage. Results of a prospective placebo-controlled double-blind trial.

    Masato Shibuya;Yoshio Suzuki;Kenichiro Sugita;Isamu Saito

  • Calmodulin and the cell cycle: Involvement in regulation of cell-cycle progression

    James G. Chafouleas;Wade E. Bolton;Hiroyoshi Hidaka;Aubrey E. Boyd

  • Tissue-specific expression of three distinct types of rabbit protein kinase C

    Shigeo Ohno;Hiroshi Kawasaki;Shinobu Imajoh;Koichi Suzuki

  • Hydrophobic regions function in calmodulin-enzyme(s) interactions.

    T Tanaka;H Hidaka

  • Calcium-regulated modulator protein interacting agents inhibit smooth muscle calcium-stimulated protein kinase and ATPase.

    Hiroyoshi Hidaka;Tokuo Yamaki;Michiko Naka;Toshio Tanaka

  • The novel and specific Rho-kinase inhibitor (S)-(+)-2-methyl-1-[(4-methyl-5-isoquinoline)sulfonyl]-homopiperazine as a probing molecule for Rho-kinase-involved pathway.

    Yasuharu Sasaki;Masaaki Suzuki;Hiroyoshi Hidaka

  • Ca2+-calmodulin-dependent phosphorylation and platelet secretion.

    Masakatsu Nishikawa;Toshio Tanaka;Hiroyoshi Hidaka

  • Phorbol ester-induced activation of human platelets is associated with protein kinase C phosphorylation of myosin light chains

    Michiko Naka;Masakatsu Nishikawa;Robert S. Adelstein;Hiroyoshi Hidaka

  • Protein kinase C modulates in vitro phosphorylation of the smooth muscle heavy meromyosin by myosin light chain kinase.

    M Nishikawa;J R Sellers;R S Adelstein;H Hidaka

  • Development of specific Rho-kinase inhibitors and their clinical application.

    Masahiro Tamura;Hiroshi Nakao;Hideo Yoshizaki;Masami Shiratsuchi

  • Selective inhibitors of Ca2+-binding modulator of phosphodiesterase produce vascular relaxation and inhibit actin-myosin interaction.

    Hiroyoshi Hidaka;Tokuo Yamaki;Tsuyoshi Totsuka;Masahisa Asano

  • Effects of Cilostazol, a Selective cAMP Phosphodiesterase Inhibitor on the Contraction of Vascular Smooth Muscle

    Toshio Tanaka;Tomohiko Ishikawa;Masatoshi Hagiwara;Koji Onoda

  • Regulation of Neuronal Nitric-oxide Synthase by Calmodulin Kinases

    Yuji Hayashi;Masahiro Nishio;Yasuhito Naito;Hisayuki Yokokura

Frequent Co-Authors

Masatoshi Hagiwara
Masatoshi Hagiwara Kyoto University
Toshio Tanaka
Toshio Tanaka Mie University
Masaki Inagaki
Masaki Inagaki Mie University
Hiroshi Tokumitsu
Hiroshi Tokumitsu Okayama University
Toshiharu Nagatsu
Toshiharu Nagatsu Fujita Health University
Masaaki Ito
Masaaki Ito Mie University
Yuji Nimura
Yuji Nimura Nagoya University
Shin'ichi Satoh
Shin'ichi Satoh National Institute of Informatics
Shun Shimohama
Shun Shimohama Sapporo Medical University
Kunio Yagi
Kunio Yagi Nagoya University

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