Masatoshi Hagiwara

Overview

Best Publications

• Phosphorylated CREB binds specifically to the nuclear protein CBP

  John C. Chrivia;Roland P. S. Kwok;Ned Lamb;Masatoshi Hagiwara

  2684
  Citations

• Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells.

  Takashi Chijiwa;Atsushi Mishima;Masatoshi Hagiwara;Mamoru Sano

  2249
  Citations

• KN-62, 1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazi ne, a specific inhibitor of Ca2+/calmodulin-dependent protein kinase II

  Hiroshi Tokumitsu;Takashi Chijiwa;Masatoshi Hagiwara;Akihiro Mizutani

  936
  Citations

• Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA.

  Daisuke Kaida;Hajime Motoyoshi;Etsu Tashiro;Takayuki Nojima

  742
  Citations

• The newly synthesized selective Ca2+calmodulin dependent protein kinase II inhibitor KN-93 reduces dopamine contents in PC12h cells

  Mariko Sumi;Kazutoshi Kiuchi;Tomohiko Ishikawa;Akira Ishii

  611
  Citations

• Transcriptional attenuation following cAMP induction requires PP-1-mediated dephosphorylation of CREB

  Masatoshi Hagiwara;Arthur Alberts;Paul Brindle;Judy Meinkoth

  599
  Citations

• A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3.

  Tetsuo Moriguchi;Noriyo Kuroyanagi;Kyoko Yamaguchi;Yukiko Gotoh

  591
  Citations

• Coupling of hormonal stimulation and transcription via the cyclic AMP-responsive factor CREB is rate limited by nuclear entry of protein kinase A

  M Hagiwara;P Brindle;A Harootunian;R Armstrong

  555
  Citations

• Manipulation of Alternative Splicing by a Newly Developed Inhibitor of Clks

  Michiko Muraki;Bisei Ohkawara;Takamitsu Hosoya;Hiroshi Onogi

  338
  Citations

• A fluorescent indicator for visualizing cAMP-induced phosphorylation in vivo.

  Yasuo Nagai;Masami Miyazaki;Ryoko Aoki;Takeru Zama

  290
  Citations

• WT1 Mutants Reveal SRPK1 to Be a Downstream Angiogenesis Target by Altering VEGF Splicing

  Elianna M. Amin;Sebastian Oltean;Jing Hua;Melissa V.R. Gammons

  271
  Citations

• Characterization of a serum response factor-like protein in Saccharomyces cerevisiae, Rlm1, which has transcriptional activity regulated by the Mpk1 (Slt2) mitogen-activated protein kinase pathway.

  Y Watanabe;G Takaesu;M Hagiwara;K Irie

  269
  Citations

• Utilization of host SR protein kinases and RNA-splicing machinery during viral replication

  Takeshi Fukuhara;Takamitsu Hosoya;Saki Shimizu;Kengo Sumi

  264
  Citations

• Regulation of vascular endothelial growth factor (VEGF) splicing from pro-angiogenic to anti-angiogenic isoforms: a novel therapeutic strategy for angiogenesis

  Dawid G. Nowak;Elianna Mohamed Amin;Emma S. Rennel;Coralie Hoareau-Aveilla

  260
  Citations

• Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A

  Yasushi Ogawa;Yosuke Nonaka;Toshiyasu Goto;Eriko Ohnishi

  260
  Citations

• Cell type-specific expression of protein kinase C isozymes in the rabbit cerebellum.

  H Hidaka;T Tanaka;K Onoda;M Hagiwara

  247
  Citations

• A newly synthesized selective casein kinase I inhibitor, N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide, and affinity purification of casein kinase I from bovine testis.

  T Chijiwa;M Hagiwara;H Hidaka

  233
  Citations

• Purification and identification of a major activator for p38 from osmotically shocked cells. Activation of mitogen-activated protein kinase kinase 6 by osmotic shock, tumor necrosis factor-alpha, and H2O2.

  Tetsuo Moriguchi;Fumiko Toyoshima;Yukiko Gotoh;Akihiro Iwamatsu

  232
  Citations

• A molecular neuroethological approach for identifying and characterizing a cascade of behaviorally regulated genes

  Kazuhiro Wada;Jason T. Howard;Patrick McConnell;Osceola Whitney

  226
  Citations

• Pharmacology of the isoquinoline sulfonamide protein kinase C inhibitors

  Hiroyoshi Hidaka;Masatoshi Hagiwara

  224
  Citations