What is he best known for?
The fields of study he is best known for:
His primary scientific interests are in Molecular biology, Cell biology, Biochemistry, Protein kinase A and Kinase.
His Molecular biology research incorporates themes from Ca2+/calmodulin-dependent protein kinase, Mitogen-activated protein kinase kinase, SR protein, RNA polymerase II and MAP kinase kinase kinase.
His studies in Cell biology integrate themes in fields like CREB, Caenorhabditis elegans and Alternative splicing.
His work deals with themes such as RNA splicing and RNA-binding protein, which intersect with Alternative splicing.
His Casein kinase 2, Casein kinase 2, alpha 1 and Open reading frame study in the realm of Biochemistry connects with subjects such as Recoverin and Neurocalcin.
The study incorporates disciplines such as CLK1, Calmodulin and Serine in addition to Kinase.
His most cited work include:
- Phosphorylated CREB binds specifically to the nuclear protein CBP (1846 citations)
- Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells. (1374 citations)
- KN-62, 1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazi ne, a specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (575 citations)
What are the main themes of his work throughout his whole career to date?
Masatoshi Hagiwara spends much of his time researching Molecular biology, Biochemistry, Cell biology, Kinase and Protein kinase A.
His study looks at the relationship between Molecular biology and topics such as Ca2+/calmodulin-dependent protein kinase, which overlap with Calmodulin.
His study in Cell biology is interdisciplinary in nature, drawing from both Regulation of gene expression, RNA splicing and Caenorhabditis elegans.
Alternative splicing is closely connected to RNA-binding protein in his research, which is encompassed under the umbrella topic of RNA splicing.
As a part of the same scientific study, he usually deals with the Kinase, concentrating on Phosphorylation and frequently concerns with CREB.
His Protein kinase A study frequently intersects with other fields, such as Myosin light-chain kinase.
He most often published in these fields:
- Molecular biology (27.38%)
- Biochemistry (25.65%)
- Cell biology (21.90%)
What were the highlights of his more recent work (between 2017-2021)?
- Neuroscience (4.03%)
- Cell biology (21.90%)
- High-functioning autism (2.31%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include Neuroscience, Cell biology, High-functioning autism, Spectrum disorder and RNA splicing.
Masatoshi Hagiwara interconnects Astrocyte, Lung, Induced pluripotent stem cell, RNA-binding protein and Transcription in the investigation of issues within Cell biology.
The various areas that Masatoshi Hagiwara examines in his RNA splicing study include Mutation, Molecular biology, Disease, Exon and Drug discovery.
The Molecular biology study which covers Gene knockdown that intersects with Intron.
His biological study deals with issues like DNA, which deal with fields such as Alternative splicing.
As a part of the same scientific family, Masatoshi Hagiwara mostly works in the field of Neurogenesis, focusing on Central nervous system and, on occasion, Kinase.
Between 2017 and 2021, his most popular works were:
- Loss of Sfpq Causes Long-Gene Transcriptopathy in the Brain (41 citations)
- In Vitro Disease Modeling of Hermansky-Pudlak Syndrome Type 2 Using Human Induced Pluripotent Stem Cell-Derived Alveolar Organoids (31 citations)
- DYRK1A and cognition: A lifelong relationship (23 citations)
In his most recent research, the most cited papers focused on:
Masatoshi Hagiwara mainly focuses on Gene, Neurodevelopmental disorder, Transcriptome, Intron and Cancer research.
His research on Gene often connects related topics like Cell biology.
In his study, Induced pluripotent stem cell is strongly linked to Single-cell analysis, which falls under the umbrella field of Cell biology.
His Intron study integrates concerns from other disciplines, such as Frameshift mutation, RNA splicing, Gene knockdown and Incontinentia pigmenti.
His Cancer research research includes elements of Immune checkpoint, Cancer cell, Ductal cells, Fatty acid and Regulation of gene expression.
His research on Transcription also deals with topics like
- Transcriptional elongation, which have a strong connection to Kinase,
- Dystrophin that connect with fields like Gene expression.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
