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Biology and Biochemistry

D-Index
106
Citations
63109
World Ranking
1126
National Ranking
672

Research.com Recognitions

  • 2009 - Member of the National Academy of Sciences

Overview

Marc Montminy is affiliated with the Salk Institute for Biological Studies in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with notable subfields including Molecular Biology, Physiology, Immunology, Surgery, and Cardiology and Cardiovascular Medicine.

The main topics of their work involve Adipose Tissue and Metabolism, Pancreatic function and diabetes, T-cell and B-cell Immunology, Metabolism, Diabetes, and Cancer, Signaling Pathways in Disease, Cardiomyopathy and Myosin Studies, and Monoclonal and Polyclonal Antibodies Research.

Marc Montminy's publication record includes articles in several scientific venues. Frequent publication forums include The Journal of Immunology, Cell Reports, bioRxiv (Cold Spring Harbor Laboratory), Communications Biology, and Metabolism.

The following are some recent research papers authored or co-authored by Montminy:

  • Activation of the adipocyte CREB/CRTC pathway in obesity (2021, Communications Biology)
  • Crtc modulates fasting programs associated with 1-C metabolism and inhibition of insulin signaling (2021, Proceedings of the National Academy of Sciences)
  • Hepatic noradrenergic innervation acts via CREB/CRTC2 to activate gluconeogenesis during cold (2024, Metabolism)
  • Transcriptional co-activator regulates melanocyte differentiation and oncogenesis by integrating cAMP and MAPK/ERK pathways (2021, Cell Reports)
  • The nutrient sensor CRTC and Sarcalumenin/thinman represent an alternate pathway in cardiac hypertrophy (2024, Cell Reports)

Collaborative work is a significant aspect of Montminy's research. Frequent co-authors include Ezra Wiater, John B. Thomas, Jeniffer B. Hernandez, Si Cave, and Qiyuan Yang.

Marc Montminy was recognized as a Member of the National Academy of Sciences in 2009.

Best Publications

  • Transcriptional regulation by the phosphorylation-dependent factor CREB

    Bernhard Mayr;Marc Montminy

  • Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

    Gustavo A. Gonzalez;Marc R. Montminy

  • Phosphorylated CREB binds specifically to the nuclear protein CBP

    John C. Chrivia;Roland P. S. Kwok;Ned Lamb;Masatoshi Hagiwara

  • The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin

    Reuben J. Shaw;Reuben J. Shaw;Katja A. Lamia;Debbie Vasquez;Seung Hoi Koo;Seung Hoi Koo

  • Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

    Marc R. Montminy;Kevin A. Sevarino;John A. Wagner;Gail Mandel

  • Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene.

    Marc R. Montminy;Louise M. Bilezikjian

  • Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB.

    K. K. Yamamoto;G. A. Gonzalez;W. H. Biggs;M. R. Montminy

  • CREB regulates hepatic gluconeogenesis through the coactivator PGC-1

    Stephan Herzig;Fanxin Long;Fanxin Long;Ulupi S. Jhala;Susan Hedrick

  • Transcriptional Regulation by Cyclic AMP

    Marc Montminy

  • CREB Is a Regulatory Target for the Protein Kinase Akt/PKB

    Keyong Du;Marc Montminy

  • CREB and the CRTC co-activators: sensors for hormonal and metabolic signals.

    Judith Y. Altarejos;Marc Montminy

  • A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence

    Gustavo A. Gonzalez;Karen K. Yamamoto;Wolfgang H. Fischer;David Karr

  • Role of CBP/P300 in nuclear receptor signalling

    Debabrata Chakravarti;Vickie J. LaMorte;Michael C. Nelson;Toshihiro Nakajima

  • TRB3: A tribbles Homolog That Inhibits Akt/PKB Activation by Insulin in Liver

    Keyong Du;Stephan Herzig;Rohit N. Kulkarni;Marc Montminy

  • The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism

    Seung Hoi Koo;Lawrence Flechner;Ling Qi;Xinmin Zhang

  • Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues

    Xinmin Zhang;Duncan T. Odom;Seung Hoi Koo;Michael D. Conkright

  • Activation of cAMP and mitogen responsive genes relies on a common nuclear factor

    J. Arias;A. S. Alberts;A. S. Alberts;P. Brindle;Francois-Xavier Claret

  • Solution structure of the KIX domain of CBP bound to the transactivation domain of CREB: a model for activator:coactivator interactions.

    Ishwar Radhakrishnan;Gabriela C Pérez-Alvarado;David Parker;H.Jane Dyson

  • Expression of murine STF-1, a putative insulin gene transcription factor, in beta cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny

    Y. Guz;M. R. Montminy;R. Stein;J. Leonard

  • Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus

    Maciej T. Malecki;Ulupi S. Jhala;Anthony Antonellis;Liz Fields

Frequent Co-Authors

Paul K. Brindle
Paul K. Brindle St. Jude Children's Research Hospital
John R. Yates
John R. Yates Scripps Research Institute
Stephan Herzig
Stephan Herzig Technical University of Munich
Hiroshi Asahara
Hiroshi Asahara Tokyo Medical and Dental University
Ronald M. Evans
Ronald M. Evans Salk Institute for Biological Studies
Reuben J. Shaw
Reuben J. Shaw Salk Institute for Biological Studies
Richard H. Goodman
Richard H. Goodman Oregon Health & Science University
James R. Feramisco
James R. Feramisco University of California, San Diego
Peter E. Wright
Peter E. Wright Scripps Research Institute
Lewis C. Cantley
Lewis C. Cantley Harvard University

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