Reuben J. Shaw

Overview

Best Publications

• Guidelines for the use and interpretation of assays for monitoring autophagy

  Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  8665
  Citations

• Resveratrol improves health and survival of mice on a high-calorie diet

  Joseph A. Baur;Kevin J. Pearson;Nathaniel O Price;Hamish A. Jamieson

  5269
  Citations

• AMPK phosphorylation of raptor mediates a metabolic checkpoint.

  Dana M. Gwinn;David B. Shackelford;Daniel F. Egan;Maria M. Mihaylova

  4269
  Citations

• The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

  Maria M. Mihaylova;Reuben J. Shaw

  3004
  Citations

• AMPK: guardian of metabolism and mitochondrial homeostasis.

  Sébastien Herzig;Reuben J. Shaw

  2913
  Citations

• Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

  Daniel F. Egan;David B. Shackelford;Maria M. Mihaylova;Sara R. Gelino

  2661
  Citations

• Ras, PI(3)K and mTOR signalling controls tumour cell growth.

  Reuben J. Shaw;Lewis C. Cantley

  2564
  Citations

• The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin

  Reuben J. Shaw;Reuben J. Shaw;Katja A. Lamia;Debbie Vasquez;Seung Hoi Koo;Seung Hoi Koo

  2318
  Citations

• The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

  Reuben J. Shaw;Monica Kosmatka;Nabeel Bardeesy;Rebecca L. Hurley

  2089
  Citations

• The LKB1-AMPK pathway: metabolism and growth control in tumour suppression.

  David B. Shackelford;Reuben J. Shaw

  2059
  Citations

• AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice.

  Yu Li;Shanqin Xu;Maria M. Mihaylova;Bin Zheng

  1726
  Citations

• AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance

  Daniel Garcia;Reuben J. Shaw

  1524
  Citations

• AMPK and PPARδ Agonists Are Exercise Mimetics

  Vihang A Narkar;Michael Downes;Ruth T. Yu;Emi Embler

  1452
  Citations

• The LKB1 tumor suppressor negatively regulates mTOR signaling

  Reuben J Shaw;Nabeel Bardeesy;Brendan D Manning;Lyle Lopez

  1258
  Citations

• AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation.

  Katja A. Lamia;Uma M. Sachdeva;Luciano DiTacchio;Elliot C. Williams

  973
  Citations

• AMP-activated protein kinase mediates mitochondrial fission in response to energy stress

  Erin Quan Toyama;Sébastien Herzig;Julien Courchet;Tommy L. Lewis

  968
  Citations

• The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR.

  Daniel F Egan;Joungmok Kim;Reuben J Shaw;Kun-Liang Guan

  744
  Citations

• LKB1 and AMP‐activated protein kinase control of mTOR signalling and growth

  Reuben J. Shaw

  728
  Citations

• Glucose metabolism and cancer.

  Reuben J Shaw

  691
  Citations

• Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates

  Daniel F. Egan;Matthew G.H. Chun;Mitchell Vamos;Haixia Zou

  675
  Citations