Marc Foretz mainly focuses on AMPK, Internal medicine, Endocrinology, AMP-activated protein kinase and Protein kinase A. AMPK is a subfield of Cell biology that Marc Foretz tackles. His biological study spans a wide range of topics, including Tumor suppressor gene, Leukemia and Fatty liver.
The concepts of his AMP-activated protein kinase study are interwoven with issues in Snf3, Glucose uptake, mTORC1, Adiponectin and Mitochondrion. The Protein kinase A study combines topics in areas such as Glycolysis and P70-S6 Kinase 1. His Type 2 diabetes research incorporates elements of Pharmacology and Biguanide.
His scientific interests lie mostly in AMPK, Internal medicine, Endocrinology, Protein kinase A and AMP-activated protein kinase. His studies in AMPK integrate themes in fields like Metformin, Glucose uptake and Skeletal muscle. His research investigates the connection between Metformin and topics such as Type 2 diabetes that intersect with problems in Biguanide.
His studies deal with areas such as Signal transduction and Adenylate kinase as well as Protein kinase A. His AMP-activated protein kinase study integrates concerns from other disciplines, such as Lipogenesis, Catabolism, Enzyme activator, Myogenesis and Mitochondrion. Marc Foretz focuses mostly in the field of Cell biology, narrowing it down to topics relating to Inflammation and, in certain cases, Phagocytosis.
The scientist’s investigation covers issues in AMPK, Internal medicine, Endocrinology, Cell biology and Protein kinase A. His research on AMPK focuses in particular on AMP-activated protein kinase. His study in Endocrinology is interdisciplinary in nature, drawing from both Nonalcoholic fatty liver disease, Integrin alpha M, Knockout mouse and Phosphorylation.
His Cell biology research is multidisciplinary, incorporating elements of Inflammation, TFEB and Immune system. Marc Foretz usually deals with Protein kinase A and limits it to topics linked to Activator and Myeloid and Proinflammatory cytokine. His work in Metformin addresses issues such as Gluconeogenesis, which are connected to fields such as Type 2 Diabetes Mellitus, Mitochondrial respiratory chain, Diabetes mellitus and Gut flora.
His primary scientific interests are in AMPK, Cell biology, Endocrinology, Internal medicine and Metformin. His AMPK study results in a more complete grasp of Protein kinase A. His Protein kinase A study incorporates themes from Small molecule, Energy homeostasis and Drug discovery.
His study on PI3K/AKT/mTOR pathway is often connected to Folliculin as part of broader study in Cell biology. Marc Foretz combines subjects such as Type 2 Diabetes Mellitus, PTEN, Pharmacology and Mitochondrial respiratory chain with his study of Metformin. His Carbohydrate metabolism research integrates issues from Gut flora, Glucose uptake, Gluconeogenesis, Diabetes mellitus and Skeletal muscle.
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Cellular and molecular mechanisms of metformin: an overview
Benoit Viollet;Benoit Viollet;Benoit Viollet;Bruno Guigas;Nieves Sanz Garcia;Nieves Sanz Garcia;Nieves Sanz Garcia;Jocelyne Leclerc;Jocelyne Leclerc;Jocelyne Leclerc.
Clinical Science (2012)
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state.
Marc Foretz;Sophie Hébrard;Jocelyne Leclerc;Elham Zarrinpashneh.
Journal of Clinical Investigation (2010)
Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes
Marc Foretz;Colette Guichard;Pascal Ferré;Fabienne Foufelle.
Proceedings of the National Academy of Sciences of the United States of America (1999)
Metformin: From Mechanisms of Action to Therapies
Marc Foretz;Marc Foretz;Marc Foretz;Bruno Guigas;Luc Bertrand;Michael Pollak.
Cell Metabolism (2014)
AMP-Activated Protein Kinase–Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol
Jee Hyun Um;Sung-Jun Park;Hyeog Kang;Shutong Yang.
Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP
Russell A. Miller;Qingwei Chu;Jianxin Xie;Marc Foretz;Marc Foretz;Marc Foretz.
ADD1/SREBP-1c Is Required in the Activation of Hepatic Lipogenic Gene Expression by Glucose
Marc Foretz;Corinne Pacot;Isabelle Dugail;Patricia Lemarchand.
Molecular and Cellular Biology (1999)
Characterization of the Role of AMP-Activated Protein Kinase in the Regulation of Glucose-Activated Gene Expression Using Constitutively Active and Dominant Negative Forms of the Kinase
Angela Woods;Dalila Azzout-Marniche;Marc Foretz;Silvie C. Stein.
Molecular and Cellular Biology (2000)
5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments.
Keith R. Laderoute;Khalid Amin;Joy M. Calaoagan;Merrill Knapp.
Molecular and Cellular Biology (2006)
Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders
Benoit Viollet;Marc Foretz;Bruno Guigas;Sandrine Horman.
The Journal of Physiology (2006)
Profile was last updated on December 6th, 2021.
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