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Medicine

D-Index
86
Citations
32222
World Ranking
13972
National Ranking
452

Overview

Marc Foretz is affiliated with Université Paris Cité in France. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions in Molecular Biology, Physiology, Surgery, Endocrinology, Diabetes and Metabolism, and Genetics.

Their work focuses on several main topics, including:

  • Metabolism, Diabetes, and Cancer
  • Pancreatic function and diabetes
  • Adipose Tissue and Metabolism
  • Diet and metabolism studies
  • Diabetes Treatment and Management
  • Diet, Metabolism, and Disease
  • Gut microbiota and health

Marc Foretz has authored numerous papers, among which the following are notable:

  • Metformin: update on mechanisms of action and repurposing potential, 2023, Nature Reviews Endocrinology
  • Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy, 2022, Nature Communications
  • Direct AMPK Activation Corrects NASH in Rodents Through Metabolic Effects and Direct Action on Inflammation and Fibrogenesis, 2021, Hepatology Communications
  • Inducible deletion of skeletal muscle AMPKα reveals that AMPK is required for nucleotide balance but dispensable for muscle glucose uptake and fat oxidation during exercise, 2020, Molecular Metabolism
  • Lkb1 suppresses amino acid-driven gluconeogenesis in the liver, 2020, Nature Communications

The venues that frequently publish Foretz's work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Molecular Metabolism
  • Diabetes
  • Free Radical Biology and Medicine

Foretz collaborates often with a core group of researchers, such as:

  • Benoı̂t Viollet
  • Bruno Guigas
  • Christian Castro
  • Daniel J. Brooks
  • Marc N. Wein

Best Publications

  • Cellular and molecular mechanisms of metformin: an overview

    Benoit Viollet;Benoit Viollet;Benoit Viollet;Bruno Guigas;Nieves Sanz Garcia;Nieves Sanz Garcia;Nieves Sanz Garcia;Jocelyne Leclerc;Jocelyne Leclerc;Jocelyne Leclerc

  • Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

    Marc Foretz;Sophie Hébrard;Jocelyne Leclerc;Elham Zarrinpashneh

  • Metformin: From Mechanisms of Action to Therapies

    Marc Foretz;Bruno Guigas;Luc Bertrand;Michael Pollak

  • Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP

    Russell A. Miller;Qingwei Chu;Jianxin Xie;Marc Foretz;Marc Foretz;Marc Foretz

  • Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes

    Marc Foretz;Colette Guichard;Pascal Ferré;Fabienne Foufelle

  • AMP-Activated Protein Kinase–Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol

    Jee Hyun Um;Sung-Jun Park;Hyeog Kang;Shutong Yang

  • Mitochondrial fission and remodelling contributes to muscle atrophy

    Vanina Romanello;Eleonora Guadagnin;Ligia Gomes;Ira Roder

  • ADD1/SREBP-1c Is Required in the Activation of Hepatic Lipogenic Gene Expression by Glucose

    Marc Foretz;Corinne Pacot;Isabelle Dugail;Patricia Lemarchand

  • Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders

    Benoit Viollet;Marc Foretz;Bruno Guigas;Sandrine Horman

  • 5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments.

    Keith R. Laderoute;Khalid Amin;Joy M. Calaoagan;Merrill Knapp

  • Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status

    Amy R. Cameron;Vicky L. Morrison;Daniel Levin;Mohapradeep Mohan

  • Characterization of the Role of AMP-Activated Protein Kinase in the Regulation of Glucose-Activated Gene Expression Using Constitutively Active and Dominant Negative Forms of the Kinase

    Angela Woods;Dalila Azzout-Marniche;Marc Foretz;Silvie C. Stein

  • AMP-activated protein kinase in the regulation of hepatic energy metabolism: from physiology to therapeutic perspectives

    Benoit Viollet;Bruno Guigas;Bruno Guigas;Jocelyne Leclerc;Jocelyne Leclerc;Sophie Hébrard;Sophie Hébrard

  • Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus

    Marc Foretz;Marc Foretz;Marc Foretz;Bruno Guigas;Benoit Viollet;Benoit Viollet;Benoit Viollet

  • Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase

    Olga Göransson;Andrew McBride;Simon A. Hawley;Fiona A. Ross

  • Short-Term Overexpression of a Constitutively Active Form of AMP-Activated Protein Kinase in the Liver Leads to Mild Hypoglycemia and Fatty Liver

    Marc Foretz;Nicolas Ancellin;Fabrizio Andreelli;Yannick Saintillan

  • AMPK inhibition in health and disease.

    Benoit Viollet;Sandrine Horman;Jocelyne Leclerc;Louise Lantier

  • AMPKα1 regulates macrophage skewing at the time of resolution of inflammation during skeletal muscle regeneration

    Rémi Mounier;Marine Théret;Marine Théret;Marine Théret;Ludovic Arnold;Ludovic Arnold;Sylvain Cuvellier;Sylvain Cuvellier;Sylvain Cuvellier

  • Intestinal Gluconeogenesis Is a Key Factor for Early Metabolic Changes after Gastric Bypass but Not after Gastric Lap-Band in Mice

    Stephanie Troy;Maud Soty;Maud Soty;Lara Ribeiro;Laure Laval;Laure Laval

  • AMPK in skeletal muscle function and metabolism.

    Rasmus Kjøbsted;Janne R. Hingst;Joachim Fentz;Marc Foretz;Marc Foretz;Marc Foretz

Frequent Co-Authors

Benoit Viollet
Benoit Viollet Institut Cochin
Kei Sakamoto
Kei Sakamoto University of Copenhagen
Pascal Ferré
Pascal Ferré Sorbonne University
Bernard Thorens
Bernard Thorens University of Lausanne
Luc Bertrand
Luc Bertrand Université Catholique de Louvain
Fabienne Foufelle
Fabienne Foufelle Sorbonne University
Sophie Vaulont
Sophie Vaulont Université Paris Cité
Ramnik J. Xavier
Ramnik J. Xavier Broad Institute
Louis Hue
Louis Hue Université Catholique de Louvain
Mary L. Bouxsein
Mary L. Bouxsein Beth Israel Deaconess Medical Center

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