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Biology and Biochemistry

D-Index
58
Citations
12786
World Ranking
13127
National Ranking
363

Overview

Eleanor J. Mackie is affiliated with the University of Melbourne in Australia and has a research portfolio focused primarily on medicine and biochemistry, genetics, and molecular biology. Their work spans several specialized subfields, including equine science, hematology, surgery, orthopedics and sports medicine, and genetics.

The main topics explored by Mackie involve veterinary equine medical research, blood coagulation and thrombosis mechanisms, sports injuries and prevention, genetic and phenotypic traits in livestock, osteoarthritis treatment and mechanisms, shoulder injury and treatment, and protease and inhibitor mechanisms.

The scientist has published articles in a variety of academic venues with multiple contributions to:

  • Equine Veterinary Journal
  • Bone Reports
  • Journal of Periodontal Research
  • Journal of Anatomy
  • The Prostate

Frequent collaborators in their research include Babatunde A. Ayodele, Charles N. Pagel, Reza Sanaei, R. Chris Whitton, and Peta L. Hitchens.

Recent papers by Eleanor J. Mackie cover a range of topics such as bone microstructure in racehorses, vascular characteristics related to racing performance, stem cell osteogenesis, inflammatory bone loss in periodontal disease, and imaging techniques for microdamage in bone. Selected publications include:

  • Microstructural properties of the proximal sesamoid bones of Thoroughbred racehorses in training (2020, Equine Veterinary Journal)
  • Associations between the radiographic appearance of vascular channels in proximal sesamoid bones, their microstructural characteristics and past racing performance in Thoroughbreds (2020, Equine Veterinary Journal)
  • Protease-activated receptor-2 promotes osteogenesis in skeletal mesenchymal stem cells at the expense of adipogenesis: Involvement of interleukin-6 (2021, Bone Reports)
  • Effect of a protease-activated receptor-2 antagonist (GB88) on inflammation-related loss of alveolar bone in periodontal disease (2023, Journal of Periodontal Research)
  • Assessment of subchondral bone microdamage quantification using contrast-enhanced imaging techniques (2024, Journal of Anatomy)

Best Publications

  • Tenascin: an extracellular matrix protein involved in tissue interactions during fetal development and oncogenesis

    Ruth Chiquet-Ehrismann;Eleanor J. Mackie;Carolyn A. Pearson;Teruyo Sakakura

  • Endochondral ossification: how cartilage is converted into bone in the developing skeleton.

    E.J. Mackie;Y.A. Ahmed;L. Tatarczuch;K.-S. Chen

  • Intracortical remodelling and porosity in the distal radius and post-mortem femurs of women: a cross-sectional study

    Roger M D Zebaze;Ali Ghasem-Zadeh;Ann Bohte;Sandra Iuliano-Burns

  • Induction of tenascin in healing wounds.

    E J Mackie;W Halfter;D Liverani

  • The skeleton: a multi-functional complex organ. The growth plate chondrocyte and endochondral ossification

    Eleanor J Mackie;Liliana Tatarczuch;Michiko Mirams

  • Osteoblasts: novel roles in orchestration of skeletal architecture.

    E.J. Mackie

  • Tenascin is associated with chondrogenic and osteogenic differentiation in vivo and promotes chondrogenesis in vitro.

    E J Mackie;I Thesleff;R Chiquet-Ehrismann

  • Tenascin is a stromal marker for epithelial malignancy in the mammary gland.

    Eleanor J. Mackie;Ruth Chiquet-Ehrismann;Carolyn Adams Pearson;Yutaka Inaguma

  • The distribution of tenascin coincides with pathways of neural crest cell migration.

    E. J. Mackie;Richard P Tucker;W. Halfter;R. Chiquet-Ehrismann

  • Arginine-specific protease from Porphyromonas gingivalis activates protease-activated receptors on human oral epithelial cells and induces interleukin-6 secretion

    Afrodite Lourbakos;Jan Potempa;James Travis;Michael R. D'Andrea

  • Changes in the distribution of tenascin during tooth development.

    I. Thesleff;E. Mackie;S. Vainio;R. Chiquet-Ehrismann

  • Epithelial induction of stromal tenascin in the mouse mammary gland: from embryogenesis to carcinogenesis.

    Yutaka Inaguma;Moriaki Kusakabe;Eleanor J. Mackie;Carolyn A. Pearson

  • Cleavage and activation of proteinase‐activated receptor‐2 on human neutrophils by gingipain‐R from Porphyromonas gingivalis

    Afrodite Lourbakos;Carla Chinni;Philip E Thompson;Jan Potempa

  • The tenascin-C knockout revisited.

    Eleanor J. Mackie;Richard P Tucker

  • Tenascin-C and human tendon degeneration.

    G. P. Riley;R. L. Harrall;T. E. Cawston;B. L. Hazleman

  • Expression of tenascin by vascular smooth muscle cells. Alterations in hypertensive rats and stimulation by angiotensin II.

    E. J. Mackie;T. Scott-Burden;A. W. A. Hahn;F. Kern

  • Tenascin expression in the mouse: in situ localization and induction in vitro by bFGF

    Richard P. Tucker;James A. Hammarback;David A. Jenrath;Eleanor J. Mackie

  • Osteopontin and skeletal muscle myoblasts: Association with muscle regeneration and regulation of myoblast function in vitro

    Kitipong Uaesoontrachoon;Hyun-Jin Yoo;Elizabeth M. Tudor;Robert N. Pike

  • Stimulation of bone formation in vivo by transforming growth factor-β: Remodeling of woven bone and lack of inhibition by indomethacin

    E.J. Mackie;U. Trechsel

  • The high-molecular-weight J1 glycoproteins are immunochemically related to tenascin

    Andreas Faissner;Jan Kruse;Ruth Chiquet-Ehrismann;Eleanor Mackie

Frequent Co-Authors

Robert N. Pike
Robert N. Pike La Trobe University
Natalie A. Sims
Natalie A. Sims St Vincents Institute of Medical Research
Ruth Chiquet-Ehrismann
Ruth Chiquet-Ehrismann Friedrich Miescher Institute
Richard P. Tucker
Richard P. Tucker University of California, Davis
T. John Martin
T. John Martin St Vincents Institute of Medical Research
Ego Seeman
Ego Seeman University of Melbourne
Irma Thesleff
Irma Thesleff University of Helsinki
Tim E. Cawston
Tim E. Cawston Newcastle University
Gordon K. Smyth
Gordon K. Smyth Walter and Eliza Hall Institute of Medical Research
Jan Potempa
Jan Potempa University of Louisville

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