Tim E. Cawston

Overview

Best Publications

• A rapid and reproducible assay for collagenase using [1-14C]acetylated collagen.

  Tim E. Cawston;Alan J. Barrett

  483
  Citations

• Tendon degeneration and chronic shoulder pain: changes in the collagen composition of the human rotator cuff tendons in rotator cuff tendinitis.

  G P Riley;R L Harrall;C R Constant;M D Chard

  473
  Citations

• Purification of rabbit bone inhibitor of collagenase.

  T E Cawston;W A Galloway;E Mercer;G Murphy

  470
  Citations

• Metalloproteinase inhibitors and the prevention of connective tissue breakdown.

  T.E. Cawston

  362
  Citations

• Actions of IL-1 are selectively controlled by p38 mitogen-activated protein kinase: regulation of prostaglandin H synthase-2, metalloproteinases, and IL-6 at different levels.

  S H Ridley;S J Sarsfield;J C Lee;H F Bigg

  361
  Citations

• Understanding the role of tissue degrading enzymes and their inhibitors in development and disease.

  Tim E. Cawston;Amy J. Wilson

  317
  Citations

• [52] Mammalian collagenases

  Tim E. Cawston;Gillian Murphy

  314
  Citations

• The modulation of matrix metalloproteinase and ADAM gene expression in human chondrocytes by interleukin‐1 and oncostatin M: A time‐course study using real‐time quantitative reverse transcription–polymerase chain reaction

  P. J. T. Koshy;C. J. Lundy;A. D. Rowan;S. Porter

  291
  Citations

• Glycosaminoglycans of human rotator cuff tendons: changes with age and in chronic rotator cuff tendinitis.

  G P Riley;R L Harrall;C R Constant;M D Chard

  283
  Citations

• Rotator cuff degeneration and lateral epicondylitis: a comparative histological study.

  M D Chard;T E Cawston;G P Riley;G A Gresham

  282
  Citations

• Interleukin 17 induces cartilage collagen breakdown: novel synergistic effects in combination with proinflammatory cytokines

  P J Koshy;N Henderson;C Logan;P F Life

  263
  Citations

• Purification and characterization of a rabbit bone metalloproteinase that degrades proteoglycan and other connective-tissue components.

  W A Galloway;G Murphy;J D Sandy;J Gavrilovic

  257
  Citations

• The role of oncostatin M in animal and human connective tissue collagen turnover and its localization within the rheumatoid joint

  T. E. Cawston;V. A. Curry;C. A. Summers;I. M. Clark

  256
  Citations

• Distribution of collagenase and tissue inhibitor of metalloproteinases (TIMP) in colorectal tumours.

  Robert E. Hewitt;Iain H. Leach;Desmond G. Powe;Ian M. Clark

  255
  Citations

• Leptin produced by joint white adipose tissue induces cartilage degradation via upregulation and activation of matrix metalloproteinases

  Wang Hui;Gary J Litherland;Martina S Elias;Gareth I Kitson

  245
  Citations

• The interaction of purified rabbit bone collagenase with purified rabbit bone metalloproteinase inhibitor.

  T E Cawston;G Murphy;E Mercer;W A Galloway

  234
  Citations

• An inhibitor of collagenase from human amniotic fluid. Purification, characterization and action on metalloproteinases

  G Murphy;T E Cawston;J J Reynolds

  231
  Citations

• The measurement of collagenase, tissue inhibitor of metalloproteinases (timp), and collagenase—timp complex in synovial fluids from patients with osteoarthritis and rheumatoid arthritis

  I. M. Clark;L. K. Powell;S. Ramsey;B. L. Hazleman

  227
  Citations

• Matrix metalloproteinases and TIMPs: properties and implications for the rheumatic diseases

  Tim Cawston

  226
  Citations

• Collagenase: a key enzyme in collagen turnover.

  WD Shingleton;DJ Hodges;P Brick;TE Cawston

  216
  Citations