Andrew D. Rowan

Overview

Best Publications

• The Comparative Role of Activator Protein 1 and Smad Factors in the Regulation of Timp-1 and MMP-1 Gene Expression by Transforming Growth Factor-β1 *

  Marie-Claire Hall;David A. Young;Jasmine G. Waters;Andrew D. Rowan

  328
  Citations

• The modulation of matrix metalloproteinase and ADAM gene expression in human chondrocytes by interleukin‐1 and oncostatin M: A time‐course study using real‐time quantitative reverse transcription–polymerase chain reaction

  P. J. T. Koshy;C. J. Lundy;A. D. Rowan;S. Porter

  291
  Citations

• The cysteine proteinases of the pineapple plant.

  A D Rowan;D J Buttle;A J Barrett

  288
  Citations

• Interleukin 17 induces cartilage collagen breakdown: novel synergistic effects in combination with proinflammatory cytokines

  P J Koshy;N Henderson;C Logan;P F Life

  263
  Citations

• The role of oncostatin M in animal and human connective tissue collagen turnover and its localization within the rheumatoid joint

  T. E. Cawston;V. A. Curry;C. A. Summers;I. M. Clark

  256
  Citations

• Rat procathepsin B. Proteolytic processing to the mature form in vitro.

  A D Rowan;P Mason;L Mach;J S Mort

  245
  Citations

• Leptin produced by joint white adipose tissue induces cartilage degradation via upregulation and activation of matrix metalloproteinases

  Wang Hui;Gary J Litherland;Martina S Elias;Gareth I Kitson

  245
  Citations

• Activity of matrix metalloproteinase-9 against native collagen types I and III

  Heather F. Bigg;Andrew D. Rowan;Michael D. Barker;Tim E. Cawston

  196
  Citations

• Synergistic effects of glycoprotein 130 binding cytokines in combination with interleukin-1 on cartilage collagen breakdown.

  A. D. Rowan;P. J. T. Koshy;W. D. Shingleton;B. A. Degnan

  193
  Citations

• The mammalian chitinase-like lectin, YKL-40, binds specifically to type I collagen and modulates the rate of type I collagen fibril formation.

  Heather F. Bigg;Robin Wait;Andrew D. Rowan;Tim E. Cawston

  188
  Citations

• Stem bromelain: amino acid sequence and implications for weak binding of cystatin.

  Anka Ritonja;Andrew D. Rowan;David J. Buttle;Neil D. Rawlings

  182
  Citations

• Germline APC variants in patients with multiple colorectal adenomas, with evidence for the particular importance of E1317Q

  H Lamlum;N Al Tassan;E Jaeger;I Frayling

  179
  Citations

• Oxidative changes and signalling pathways are pivotal in initiating age-related changes in articular cartilage

  Wang Hui;David A Young;Andrew D Rowan;Xin Xu

  172
  Citations

• An association between the CTLA4 exon 1 polymorphism and early rheumatoid arthritis with autoimmune endocrinopathies

  B. Vaidya;S. H. S. Pearce;S. Charlton;N. Marshall

  172
  Citations

• Matrix metalloproteinase 10 promotion of collagenolysis via procollagenase activation: Implications for cartilage degradation in arthritis

  H. E. Barksby;J. M. Milner;A. M. Patterson;N. J. Peake

  158
  Citations

• Low-level microsatellite instability occurs in most colorectal cancers and is a nonrandomly distributed quantitative trait.

  Sarah Halford;Peter Sasieni;Andrew Rowan;Harpreet Wasan

  154
  Citations

• Oncostatin M in combination with tumor necrosis factor alpha induces cartilage damage and matrix metalloproteinase expression in vitro and in vivo.

  W. Hui;A. D. Rowan;C. D. Richards;T. E. Cawston

  149
  Citations

• Mechanisms of loss of HLA class I expression on colorectal tumor cells.

  M. Browning;F. Petronzelli;D. Bicknell;P. Krausa

  145
  Citations

• The regulation of MMPs and TIMPs in cartilage turnover

  Tim Cawston;Caron Billington;Catherine Cleaver;Sarah Elliott

  142
  Citations

• Interleukin-1 in combination with oncostatin M up-regulates multiple genes in chondrocytes - Implications for cartilage destruction and repair

  H. E. Barksby;W. Hui;I. Wappler;H. H. Peters

  138
  Citations