D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 57 Citations 7,919 151 World Ranking 9664 National Ranking 738

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Cancer

His primary scientific interests are in Oncostatin M, Matrix metalloproteinase, Chondrocyte, Immunology and Biochemistry. His Oncostatin M study typically links adjacent topics like Molecular biology. Andrew D. Rowan combines subjects such as Signal transduction, Collagenase and Pathology with his study of Matrix metalloproteinase.

His work in Pathology covers topics such as Tumor necrosis factor alpha which are related to areas like In vivo. His research in the fields of Affinity chromatography, Cysteine, Bromelain and Collagen, type I, alpha 1 overlaps with other disciplines such as Stem bromelain. His Cytokine research includes elements of Proinflammatory cytokine and Cell biology.

His most cited work include:

  • The Comparative Role of Activator Protein 1 and Smad Factors in the Regulation of Timp-1 and MMP-1 Gene Expression by Transforming Growth Factor-β1 * (193 citations)
  • The role of oncostatin M in animal and human connective tissue collagen turnover and its localization within the rheumatoid joint (189 citations)
  • Interleukin 17 induces cartilage collagen breakdown: novel synergistic effects in combination with proinflammatory cytokines (185 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Cell biology, Matrix metalloproteinase, Oncostatin M, Immunology and Collagenase. His Cell biology study combines topics from a wide range of disciplines, such as Chondrocyte, Internal medicine and Gene expression. His Matrix metalloproteinase research incorporates themes from Arthritis, Cancer research and Pathology.

His Oncostatin M study deals with Molecular biology intersecting with In vivo. The Immunology study combines topics in areas such as Signal transduction and Gerontology. His work carried out in the field of Collagenase brings together such families of science as Hydroxyproline, Tissue inhibitor of metalloproteinase and Collagen, type I, alpha 1.

He most often published in these fields:

  • Cell biology (39.73%)
  • Matrix metalloproteinase (36.99%)
  • Oncostatin M (23.29%)

What were the highlights of his more recent work (between 2013-2021)?

  • Cell biology (39.73%)
  • Matrix metalloproteinase (36.99%)
  • Cancer research (16.44%)

In recent papers he was focusing on the following fields of study:

His main research concerns Cell biology, Matrix metalloproteinase, Cancer research, Extracellular matrix and Pathology. His Cell biology research incorporates elements of Chondrocyte, Collagenase, Immunology and Type II collagen. In his research, Oncostatin M is intimately related to p38 mitogen-activated protein kinases, which falls under the overarching field of Collagenase.

Andrew D. Rowan focuses mostly in the field of Immunology, narrowing it down to matters related to Signal transduction and, in some cases, Inflammation and Arthritis. His study in Matrix metalloproteinase is interdisciplinary in nature, drawing from both Extracellular and MAPK/ERK pathway. The various areas that Andrew D. Rowan examines in his Pathology study include Intratumor heterogeneity and Gerontology.

Between 2013 and 2021, his most popular works were:

  • Oxidative changes and signalling pathways are pivotal in initiating age-related changes in articular cartilage (76 citations)
  • Gain-of-function STAT1 mutations impair STAT3 activity in patients with chronic mucocutaneous candidiasis (CMC). (58 citations)
  • Proteinase-activated receptor 2 modulates OA-related pain, cartilage and bone pathology (42 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Cancer

Andrew D. Rowan mainly investigates Cell biology, Chondrocyte, Immunology, Pathology and Oncostatin M. Andrew D. Rowan is involved in the study of Cell biology that focuses on Extracellular matrix in particular. His biological study spans a wide range of topics, including Proteasome inhibitor, Ubiquitin and Transgene.

The study incorporates disciplines such as Inflammation and Receptor in addition to Pathology. His Oncostatin M research is multidisciplinary, incorporating elements of Molecular biology, Signal transduction, GSK-3 and Collagenase. His Molecular biology study integrates concerns from other disciplines, such as Gene silencing and Gene expression.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The Comparative Role of Activator Protein 1 and Smad Factors in the Regulation of Timp-1 and MMP-1 Gene Expression by Transforming Growth Factor-β1 *

Marie-Claire Hall;David A. Young;Jasmine G. Waters;Andrew D. Rowan.
Journal of Biological Chemistry (2003)

318 Citations

The modulation of matrix metalloproteinase and ADAM gene expression in human chondrocytes by interleukin‐1 and oncostatin M: A time‐course study using real‐time quantitative reverse transcription–polymerase chain reaction

P. J. T. Koshy;C. J. Lundy;A. D. Rowan;S. Porter.
Arthritis & Rheumatism (2002)

281 Citations

The cysteine proteinases of the pineapple plant.

A D Rowan;D J Buttle;A J Barrett.
Biochemical Journal (1990)

273 Citations

Interleukin 17 induces cartilage collagen breakdown: novel synergistic effects in combination with proinflammatory cytokines

P J Koshy;N Henderson;C Logan;P F Life.
Annals of the Rheumatic Diseases (2002)

253 Citations

The role of oncostatin M in animal and human connective tissue collagen turnover and its localization within the rheumatoid joint

T. E. Cawston;V. A. Curry;C. A. Summers;I. M. Clark.
Arthritis & Rheumatism (1998)

243 Citations

Leptin produced by joint white adipose tissue induces cartilage degradation via upregulation and activation of matrix metalloproteinases

Wang Hui;Gary J Litherland;Martina S Elias;Gareth I Kitson.
Annals of the Rheumatic Diseases (2012)

213 Citations

Synergistic effects of glycoprotein 130 binding cytokines in combination with interleukin-1 on cartilage collagen breakdown.

A. D. Rowan;P. J. T. Koshy;W. D. Shingleton;B. A. Degnan.
Arthritis & Rheumatism (2001)

190 Citations

The mammalian chitinase-like lectin, YKL-40, binds specifically to type I collagen and modulates the rate of type I collagen fibril formation.

Heather F. Bigg;Robin Wait;Andrew D. Rowan;Tim E. Cawston.
Journal of Biological Chemistry (2006)

177 Citations

Stem bromelain: amino acid sequence and implications for weak binding of cystatin.

Anka Ritonja;Andrew D. Rowan;David J. Buttle;Neil D. Rawlings.
FEBS Letters (1989)

174 Citations

Germline APC variants in patients with multiple colorectal adenomas, with evidence for the particular importance of E1317Q

H Lamlum;N Al Tassan;E Jaeger;I Frayling.
Human Molecular Genetics (2000)

174 Citations

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