David J. Buttle

Overview

Best Publications

• Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue

  Richard W. Farndale;David J. Buttle;Alan J. Barrett

  3833
  Citations

• Living tissue formed in vitro and accepted as skin-equivalent tissue of full thickness

  E Bell;HP Ehrlich;DJ Buttle;T Nakatsuji

  1474
  Citations

• Matrix synthesis and degradation in human intervertebral disc degeneration.

  C L Le Maitre;A Pockert;D J Buttle;A J Freemont

  602
  Citations

• Human cathepsin K cleaves native type I and II collagens at the N-terminal end of the triple helix

  W. Kafienah;D. Brömme;D.J. Buttle;L.J. Croucher

  435
  Citations

• Modified expression of the ADAMTS enzymes and tissue inhibitor of metalloproteinases 3 during human intervertebral disc degeneration

  Aneta J. Pockert;Stephen M. Richardson;Christine L. Le Maitre;Malcolm Lyon

  307
  Citations

• CA074 methyl ester: A proinhibitor for intracellular cathepsin B

  David J. Buttle;Mitsuo Murata;C.Graham Knight;Alan J. Barrett

  291
  Citations

• The cysteine proteinases of the pineapple plant.

  A D Rowan;D J Buttle;A J Barrett

  288
  Citations

• The two cysteine endopeptidases of legume seeds : purification and characterization by use of specific fluorometric assays

  A.A. Kembhavi;D.J. Buttle;C.G. Knight;A.J. Barrett

  241
  Citations

• Human cystatin C. role of the N-terminal segment in the inhibition of human cysteine proteinases and in its inactivation by leucocyte elastase.

  Magnus Abrahamson;Robert W Mason;Heléne Hansson;David J Buttle

  232
  Citations

• Assessment of the anthelmintic effect of natural plant cysteine proteinases against the gastrointestinal nematode, Heligmosomoides polygyrus, in vitro.

  Gillian Stepek;David J. Buttle;I.R. Duce;Ann Lowe

  202
  Citations

• Human gastrointestinal nematode infections: are new control methods required?

  Gillian Stepek;David J. Buttle;Ian R. Duce;Jerzy M. Behnke

  191
  Citations

• Stem bromelain: amino acid sequence and implications for weak binding of cystatin.

  Anka Ritonja;Andrew D. Rowan;David J. Buttle;Neil D. Rawlings

  182
  Citations

• Agonists of toll-like receptor (TLR)2 and TLR4 are unable to modulate platelet activation by adenosine diphosphate and platelet activating factor.

  Jon R. Ward;Lynne Bingle;Heather M. Judge;Simon B. Brown

  180
  Citations

• Catechins from Green Tea (Camellia sinensis) Inhibit Bovine and Human Cartilage Proteoglycan and Type II Collagen Degradation In Vitro

  Clair Adcocks;Peter Collin;David J. Buttle

  170
  Citations

• Inhibition of cartilage proteoglycan release by a specific inactivator of cathepsin b and an inhibitor of matrix metalloproteinases. evidence for two converging pathways of chondrocyte‐mediated proteoglycan degradation

  David J. Buttle;David J. Buttle;Christopher J. Handley;Mirna Z. Ilic;Jeremy Saklatvala

  170
  Citations

• Natural plant cysteine proteinases as anthelmintics

  Gillian Stepek;Jerzy M. Behnke;David J. Buttle;Ian R. Duce

  169
  Citations

• Inhibition of bone resorption by selective inactivators of cysteine proteinases.

  Peter A. Hill;David J. Buttle;Sheila J. Jones;Alan Boyde

  169
  Citations

• Degradation of type II collagen, but not proteoglycan, correlates with matrix metalloproteinase activity in cartilage explant cultures

  L. Didem Kozaci;David J. Buttle;Anthony P. Hollander

  158
  Citations

• Developing novel anthelmintics from plant cysteine proteinases

  Jerzy M Behnke;David J Buttle;Gillian Stepek;Gillian Stepek;Ann Lowe

  152
  Citations

• Expression and activity of ADAMTS-5 in synovium.

  Mireille N. Vankemmelbeke;Ingunn Holen;Anthony G. Wilson;Mirna Z. Ilic

  148
  Citations