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Biology and Biochemistry

D-Index
53
Citations
12061
World Ranking
16035
National Ranking
1270

Overview

Andrew A. Pitsillides is affiliated with the Royal Veterinary College in the United Kingdom. Their research spans multiple areas primarily within medicine and biochemistry, genetics, and molecular biology. The scientist's work frequently addresses topics related to orthopedics and sports medicine, rheumatology, molecular biology, biomedical engineering, and genetics.

The research topics covered include:

  • Osteoarthritis Treatment and Mechanisms
  • Bone health and osteoporosis research
  • Bone Metabolism and Diseases
  • Tendon Structure and Treatment
  • Bone fractures and treatments
  • Inflammatory mediators and NSAID effects
  • Alkaline Phosphatase Research Studies

Andrew A. Pitsillides has contributed to various academic journals with a focus on biomedical and biological sciences. Frequent publication venues include:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Biochemistry and Function
  • Journal of Anatomy
  • SSRN Electronic Journal

The scientist has worked collaboratively with several co-authors in their field, notably:

  • Mark Hopkinson
  • Behzâd Javaheri
  • Lucinda Evans
  • Peter Lee
  • Chavaunne T. Thorpe

Recent papers authored or co-authored by Andrew A. Pitsillides include:

  • "Heterogeneity of proteome dynamics between connective tissue phases of adult tendon," 2020, published in eLife
  • "Lasting organ-level bone mechanoadaptation is unrelated to local strain," 2020, published in Science Advances
  • "Meniscal and ligament modifications in spontaneous and post-traumatic mouse models of osteoarthritis," 2020, published in Arthritis Research & Therapy
  • "Regional variations in discrete collagen fibre mechanics within intact intervertebral disc resolved using synchrotron computed tomography and digital volume correlation," 2021, published in Acta Biomaterialia
  • "Effect of Inflammatory Signaling on Human Articular Chondrocyte Hypertrophy: Potential Involvement of Tissue Repair Macrophages," 2021, published in Cartilage

Best Publications

  • Limb proportions show developmental plasticity in response to embryo movement.

    A S Pollard;B G Charlton;J. R. Hutchinson;T O Gustafsson

  • Non-invasive axial loading of mouse tibiae increases cortical bone formation and modifies trabecular organization: A new model to study cortical and cancellous compartments in a single loaded element

    Roberto L. De Souza;Maiko Matsuura;Felix Eckstein;Simon C.F. Rawlinson

  • Mechanical strain-induced NO production by bone cells: a possible role in adaptive bone (re)modeling?

    Andrew A. Pitsillides;Simon C. F. Rawlinson;Rosemary F. L. Suswillo;Sandrine Bourrin

  • Mechanical strain stimulates nitric oxide production by rapid activation of endothelial nitric oxide synthase in osteocytes

    G Zaman;A A Pitsillides;S C F Rawlinson;R F L Suswillo

  • Cartilage biology in osteoarthritis—lessons from developmental biology

    Andrew A. Pitsillides;Frank Beier

  • Hyaluronan synthesis and degradation in cartilage and bone.

    E. R. Bastow;S. Byers;S. B. Golub;C. E. Clarkin

  • Involvement of different ion channels in osteoblasts' and osteocytes' early responses to mechanical strain.

    S.C.F. Rawlinson;A.A. Pitsillides;L.E. Lanyon

  • Using digital image correlation to determine bone surface strains during loading and after adaptation of the mouse tibia.

    Pavel Sztefek;Maximilien Vanleene;Robin Olsson;Rebecca Collinson

  • Calvarial and limb bone cells in organ and monolayer culture do not show the same early responses to dynamic mechanical strain

    Simon C. F. Rawlinson;John R. Mosley;Rosemary F. L. Suswillo;Andrew A. Pitsillides

  • Ammonia impairs neutrophil phagocytic function in liver disease

    Debbie L. Shawcross;Gavin A. K. Wright;Vanessa Stadlbauer;Stephen J. Hodges

  • Cellular aspects of the development of diarthrodial joints and articular cartilage.

    C W Archer;H Morrison;A A Pitsillides

  • Mechanical strain and fluid movement both activate extracellular regulated kinase (ERK) in osteoblast-like cells but via different signaling pathways

    H.L Jessop;S.C.F Rawlinson;A.A Pitsillides;L.E Lanyon

  • Characterizing a novel and adjustable noninvasive murine joint loading model.

    Blandine Poulet;Richard W. Hamilton;Sandra Shefelbine;Andrew A. Pitsillides

  • Evaluation of VEGF-mediated signaling in primary human cells reveals a paracrine action for VEGF in osteoblast-mediated crosstalk to endothelial cells.

    Claire E. Clarkin;Roger J. Emery;Andrew A. Pitsillides;Caroline P.D. Wheeler-Jones

  • Light microscopic characterization of the fibroblast-like synovial intimal cell (synoviocyte)

    Linda S. Wilkinson;Andrew A. Pitsillides;Jennifer G. Worrall;Jo C. W. Edwards

  • An Essential Role for the Interaction Between Hyaluronan and Hyaluronan Binding Proteins During Joint Development

    Gary P. Dowthwaite;Jo C. W. Edwards;Andrew A. Pitsillides

  • Osteocytes Use Estrogen Receptor α to Respond to Strain but Their ERα Content Is Regulated by Estrogen

    Gul Zaman;Helen L Jessop;Mariusz Muzylak;Roberto L De Souza

  • Non-invasive mouse models of post-traumatic osteoarthritis

    B. A. Christiansen;Farshid Guilak;K. A. Lockwood;S. A. Olson

  • Aging enhances a mechanically-induced reduction in tendon strength by an active process involving matrix metalloproteinase activity

    Jayesh Dudhia;Charlotte M. Scott;Edward R. C. Draper;Dick Heinegård

  • The formation of human synovial joint cavities: a possible role for hyaluronan and CD44 in altered interzone cohesion.

    J. C. W. Edwards;L. S. Wilkinson;H. M. Jones;P. Soothill

Frequent Co-Authors

Colin Farquharson
Colin Farquharson University of Edinburgh
Mark Hopkinson
Mark Hopkinson University of Sheffield
Peter D. Lee
Peter D. Lee University College London
David J. Buttle
David J. Buttle University of Sheffield
George Bou-Gharios
George Bou-Gharios University of Liverpool
Lance E. Lanyon
Lance E. Lanyon Royal Veterinary College
Alan Boyde
Alan Boyde Queen Mary University of London
John R. Hutchinson
John R. Hutchinson Royal Veterinary College
Frank Beier
Frank Beier University of Western Ontario
José Luis Millán
José Luis Millán Discovery Institute

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