What is he best known for?
The fields of study he is best known for:
- Gene
- Internal medicine
- Surgery
Christopher B. Little spends much of his time researching Cartilage, Aggrecan, Osteoarthritis, Proteoglycan and Biochemistry.
His Cartilage study integrates concerns from other disciplines, such as Extracellular matrix, Internal medicine and Endocrinology.
His Aggrecan research includes themes of ADAMTS, Glycosaminoglycan, Immunology, Aggrecanase and Cell biology.
His Osteoarthritis study is concerned with the larger field of Pathology.
In Pathology, Christopher B. Little works on issues like Animal model, which are connected to Disease process.
In his research on the topic of Biochemistry, Extracellular, Hyaluronidase, Extracellular Matrix Degradation and Organ culture is strongly related with Synovial joint.
His most cited work include:
- The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the mouse (1145 citations)
- ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro (731 citations)
- Are animal models useful for studying human disc disorders/degeneration? (472 citations)
What are the main themes of his work throughout his whole career to date?
Christopher B. Little mainly investigates Cartilage, Osteoarthritis, Pathology, Aggrecan and Cell biology.
Christopher B. Little has researched Cartilage in several fields, including Internal medicine, Matrix metalloproteinase, Arthritis and Endocrinology.
His work in Osteoarthritis covers topics such as Gene expression profiling which are related to areas like microRNA.
The Pathology study combines topics in areas such as Lumican and Intervertebral disc.
Christopher B. Little combines subjects such as ADAMTS, Proteoglycan, Biochemistry, Aggrecanase and Molecular biology with his study of Aggrecan.
His Cell biology study combines topics in areas such as Stromal cell and Immunology.
He most often published in these fields:
- Cartilage (35.76%)
- Osteoarthritis (32.78%)
- Pathology (32.12%)
What were the highlights of his more recent work (between 2018-2021)?
- Osteoarthritis (32.78%)
- Cartilage (35.76%)
- Pathology (32.12%)
In recent papers he was focusing on the following fields of study:
His main research concerns Osteoarthritis, Cartilage, Pathology, Inflammation and Stem cell.
His biological study spans a wide range of topics, including Synovitis, Stem-cell therapy, Anterior cruciate ligament, Internal medicine and Histopathology.
In his study, Blot, Molecular biology and Regeneration is strongly linked to Matrix metalloproteinase, which falls under the umbrella field of Cartilage.
His Pathology study incorporates themes from Antibody and Serology.
His Inflammation research incorporates elements of Phenotype, Implant, Drug and Arthritis.
Christopher B. Little interconnects Mesenchymal stem cell, Disease and Bioinformatics in the investigation of issues within Stem cell.
Between 2018 and 2021, his most popular works were:
- Stem Cell-Derived Extracellular Vesicles for Treating Joint Injury and Osteoarthritis. (24 citations)
- Catabolism of Fibromodulin in Developmental Rudiment and Pathologic Articular Cartilage Demonstrates Novel Roles for MMP-13 and ADAMTS-4 in C-terminal Processing of SLRPs (13 citations)
- Catabolism of Fibromodulin in Developmental Rudiment and Pathologic Articular Cartilage Demonstrates Novel Roles for MMP-13 and ADAMTS-4 in C-terminal Processing of SLRPs (13 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Internal medicine
- Surgery
His primary areas of investigation include Osteoarthritis, Cartilage, Pathology, Inflammation and Research design.
His work carried out in the field of Osteoarthritis brings together such families of science as Endocrinology, Stem cell, Metalloproteinase, Regeneration and Mesenchymal stem cell.
His Cartilage research integrates issues from Molecular biology, ADAMTS, Matrix metalloproteinase and Blot.
His work deals with themes such as Antibody and Serology, which intersect with Pathology.
Christopher B. Little interconnects Oral administration, Diclofenac, Implant and Arthritis in the investigation of issues within Inflammation.
His biological study spans a wide range of topics, including Phenotype, Disease burden and Knowledge management.
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