His primary scientific interests are in Osteoarthritis, Cartilage, Internal medicine, Chondrocyte and Pathology. His biological study spans a wide range of topics, including Surgery, Immunology, Bioinformatics and Synovial membrane. The various areas that he examines in his Cartilage study include Synovial fluid, Anterior cruciate ligament, Magnetic resonance imaging, Cell biology and Collagenase.
His work carried out in the field of Internal medicine brings together such families of science as Endocrinology and Cartilage metabolism. Jean-Pierre Pelletier has included themes like Caspase 3, Molecular biology, Kinase and Peroxisome proliferator-activated receptor in his Chondrocyte study. The Pathology study combines topics in areas such as Interleukin 1 receptor antagonist, Bone cell and Saline.
Jean-Pierre Pelletier spends much of his time researching Osteoarthritis, Internal medicine, Cartilage, Endocrinology and Pathology. His work deals with themes such as Surgery, Synovial membrane, Magnetic resonance imaging, Disease and Physical therapy, which intersect with Osteoarthritis. His research brings together the fields of Cartilage metabolism and Internal medicine.
Chondrocyte is the focus of his Cartilage research. His Chondrocyte research includes themes of Molecular biology, Kinase and Immunology. His Endocrinology study combines topics in areas such as Osteocalcin, Peroxisome proliferator-activated receptor and Osteoblast.
Jean-Pierre Pelletier mostly deals with Osteoarthritis, Internal medicine, Cartilage, Physical therapy and Surgery. His Osteoarthritis research includes elements of Adverse effect, Magnetic resonance imaging and Cohort. His study in Internal medicine is interdisciplinary in nature, drawing from both Placebo, Endocrinology and Diacerein.
His Endocrinology study incorporates themes from Inflammation, Cartilage metabolism and Matrix metalloproteinase. The concepts of his Cartilage study are interwoven with issues in Radiography, Nuclear medicine, Pathology, Knee replacement and Chondroitin sulfate. Jean-Pierre Pelletier focuses mostly in the field of Surgery, narrowing it down to matters related to Bone marrow and, in some cases, Strontium ranelate.
His primary areas of investigation include Osteoarthritis, Internal medicine, Cartilage, Surgery and Adverse effect. His research integrates issues of Urology, Placebo, Osteoporosis, Physical therapy and Chondroitin sulfate in his study of Osteoarthritis. His Internal medicine study integrates concerns from other disciplines, such as Osteocalcin, LGR5, LRP6 and WOMAC.
His research in Cartilage intersects with topics in Autophagy, Cohort, Pathology, PI3K/AKT/mTOR pathway and N-terminal telopeptide. His Adverse effect study combines topics from a wide range of disciplines, such as Celecoxib, Diclofenac and Therapeutic effect. His Protein kinase A research integrates issues from Chondrocyte and Immunology.
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Role of proinflammatory cytokines in the pathophysiology of osteoarthritis
Mohit Kapoor;Johanne Martel-Pelletier;Daniel Lajeunesse;Jean-Pierre Pelletier.
Nature Reviews Rheumatology (2011)
Osteoarthritis, an inflammatory disease: Potential implication for the selection of new therapeutic targets
Jean-Pierre Pelletier;Johanne Martel-Pelletier;Steven B. Abramson.
Arthritis & Rheumatism (2001)
The role of cytokines in osteoarthritis pathophysiology.
Julio C Fernandes;Johanne Martel-Pelletier;Jean-Pierre Pelletier.
The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes. A role in osteoarthritis.
Pascal Reboul;Jean-Pierre Pelletier;Ginette Tardif;Jean-Marie Cloutier.
Journal of Clinical Investigation (1996)
Meniscal tear and extrusion are strongly associated with progression of symptomatic knee osteoarthritis as assessed by quantitative magnetic resonance imaging
Marie-Josée Berthiaume;Jean-Pierre Raynauld;Johanne Martel-Pelletier;Françoys Labonté.
Annals of the Rheumatic Diseases (2005)
Safety and efficacy of long-term intraarticular steroid injections in osteoarthritis of the knee: A randomized, double-blind, placebo-controlled trial
Jean-Pierre Raynauld;Chris Buckland-Wright;Rupert Ward;Denis Choquette.
Arthritis & Rheumatism (2003)
Cartilage in normal and osteoarthritis conditions.
Johanne Martel-Pelletier;Christelle Boileau;Jean-Pierre Pelletier;Peter J. Roughley.
Best Practice & Research: Clinical Rheumatology (2008)
Risedronate decreases biochemical markers of cartilage degradation but does not decrease symptoms or slow radiographic progression in patients with medial compartment osteoarthritis of the knee: results of the two-year multinational knee osteoarthritis structural arthritis study.
Clifton O. Bingham;J. Chris Buckland-Wright;Patrick Garnero;Stanley B. Cohen.
Arthritis & Rheumatism (2006)
Reduced progression of experimental osteoarthritis in vivo by selective inhibition of inducible nitric oxide synthase
Jean-Pierre Pelletier;Dragan Jovanovic;Julio C. Fernandes;Pamela Manning.
Arthritis & Rheumatism (1998)
Therapeutic role of dual inhibitors of 5-LOX and COX, selective and non-selective non-steroidal anti-inflammatory drugs.
Johanne Martel-Pelletier;Daniel Lajeunesse;Pascal Reboul;Jean-Pierre Pelletier.
Annals of the Rheumatic Diseases (2003)
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