World's Best Scientists 2026 revealed!
Alan J. Grodzinsky

Alan J. Grodzinsky

D-Index & Metrics

Biology and Biochemistry

D-Index
115
Citations
43975
World Ranking
798
National Ranking
502

Research.com Recognitions

  • 1993 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

Alan J. Grodzinsky is affiliated with MIT in the United States with a research focus primarily centered in the field of Medicine. Their work includes significant contributions to subfields such as Rheumatology, Surgery, Molecular Biology, Pharmacology, and Immunology.

The scientist's recent publications address various aspects of cartilage biology, osteoarthritis, and regenerative medicine. Key papers include:

  • Creb5 establishes the competence for Prg4 expression in articular cartilage, 2021, Communications Biology
  • Biomanufacturing in low Earth orbit for regenerative medicine, 2021, Stem Cell Reports
  • Inflammatory cytokines and mechanical injury induce post-traumatic osteoarthritis-like changes in a human cartilage-bone-synovium microphysiological system, 2022, Arthritis Research & Therapy
  • Nonuniformity in Periodontal Ligament: Mechanics and Matrix Composition, 2020, Journal of Dental Research
  • Mechanobiological model for simulation of injured cartilage degradation via pro-inflammatory cytokines and mechanical stimulus, 2020, PLoS Computational Biology

Frequent coauthors in their work include Atte S. A. Eskelinen, Petri Tanska, Rami K. Korhonen, Joonas P. Kosonen, and Cristina Florea.

Alan J. Grodzinsky has published regularly in venues such as bioRxiv (Cold Spring Harbor Laboratory), PLoS Computational Biology, Osteoarthritis and Cartilage, Arthritis Research & Therapy, and Journal of Orthopaedic Research®.

The scientist's research addresses topics including:

  • Osteoarthritis Treatment and Mechanisms
  • Knee injuries and reconstruction techniques
  • Inflammatory mediators and NSAID effects
  • Cell Adhesion Molecules Research
  • RNA Research and Splicing
  • Periodontal Regeneration and Treatments
  • Total Knee Arthroplasty Outcomes

Among recognitions, Alan J. Grodzinsky was named a Fellow of the Indian National Academy of Engineering (INAE) in 1993.

Best Publications

  • Fluorometric assay of DNA in cartilage explants using Hoechst 33258.

    Young-Jo Kim;Robert L.Y. Sah;Joe-Yuan H. Doong;Alan J. Grodzinsky

  • Role of extracellular matrix assembly in interstitial transport in solid tumors.

    Paolo A. Netti;David A. Berk;Melody A. Swartz;Alan J. Grodzinsky

  • Self-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: Implications for cartilage tissue repair

    J. Kisiday;M. Jin;B. Kurz;H. Hung

  • Biosynthetic response of cartilage explants to dynamic compression.

    R. L.-Y. Sah;Young-Jo Kim;J.-Y. H. Doong;A. J. Grodzinsky

  • Mechanical compression modulates matrix biosynthesis in chondrocyte/agarose culture

    Michael D. Buschmann;Yehezkiel A. Gluzband;Alan J. Grodzinsky;Ernst B. Hunziker

  • Bioreactor cultivation conditions modulate the composition and mechanical properties of tissue-engineered cartilage.

    G. Vunjak-Novakovic;I. Martin;B. Obradovic;S. Treppo

  • Articular cartilage and osteoarthritis.

    Joseph A Buckwalter;Henry J Mankin;Alan J Grodzinsky

  • Cartilage tissue remodeling in response to mechanical forces.

    Alan J. Grodzinsky;Marc E. Levenston;Moonsoo Jin;Eliot H. Frank

  • Local myocardial insulin-like growth factor 1 (IGF-1) delivery with biotinylated peptide nanofibers improves cell therapy for myocardial infarction.

    Michael E. Davis;Patrick C. H. Hsieh;Tomosaburo Takahashi;Qing Song

  • Transcranial direct current stimulation: a computer-based human model study.

    Tim A. Wagner;Felipe Fregni;Shirley Fecteau;Alan J. Grodzinsky

  • Chondrocytes in agarose culture synthesize a mechanically functional extracellular matrix.

    Michael D. Buschmann;Yehezkiel A. Gluzband;Alan J. Grodzinsky;James H. Kimura

  • Mechanical and physicochemical determinants of the chondrocyte biosynthetic response

    Martha L. Gray;Angelina M. Pizzanelli;Alan J. Grodzinsky;Raphael C. Lee

  • Structure-dependent dynamic mechanical behavior of fibrous caps from human atherosclerotic plaques.

    R T Lee;A J Grodzinsky;E H Frank;R D Kamm

  • The effects of cross-linking of collagen-glycosaminoglycan scaffolds on compressive stiffness, chondrocyte-mediated contraction, proliferation and biosynthesis.

    C.R Lee;C.R Lee;A.J Grodzinsky;M Spector

  • Injurious mechanical compression of bovine articular cartilage induces chondrocyte apoptosis.

    Andreas M. Loening;Ian E. James;Marc E. Levenston;Alison M. Badger

  • Mechanical Regulation of Cartilage Biosynthetic Behavior: Physical Stimuli

    Young-Jo Kim;Robert L. Y. Sah;Alan J. Grodzinsky;Anna H. K. Plaas

  • Comparison of biomechanical and biochemical properties of cartilage from human knee and ankle pairs.

    Steven Treppo;Holger Koepp;Emerson C. Quan;Ada A. Cole

  • Electromechanical and physicochemical properties of connective tissue.

    Grodzinsky Aj

  • Three-dimensional head model Simulation of transcranial magnetic stimulation

    T.A. Wagner;M. Zahn;A.J. Grodzinsky;A. Pascual-Leone

  • A Molecular Model of Proteoglycan-Associated Electrostatic Forces in Cartilage Mechanics

    M. D. Buschmann;A. J. Grodzinsky

Frequent Co-Authors

John D. Sandy
John D. Sandy Rush University Medical Center
Anna Plaas
Anna Plaas Rush University Medical Center
Myron Spector
Myron Spector Brigham and Women's Hospital
Richard T. Lee
Richard T. Lee Harvard University
Rakesh K. Jain
Rakesh K. Jain Harvard University
Ernst B. Hunziker
Ernst B. Hunziker University of Bern
Lawrence J. Bonassar
Lawrence J. Bonassar Cornell University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Biology and Biochemistry opens doors to diverse online programs and emerging career paths within healthcare, nutrition, and medical informatics. Many students look to specialized programs that build on biological sciences, allowing for advanced roles and interdisciplinary opportunities.

For those interested in mental health, consider pmhnp programs, which prepare graduates for clinical practice as psychiatric mental health nurse practitioners. Alternatively, health and wellness enthusiasts may pursue a holistic nutrition degree to integrate biology with nutrition counseling skills.

Careers in healthcare management are also expanding rapidly. If you’re considering leadership or administrative roles, check the healthcare mba cost for completing your business education online.

Finally, medical coding remains a vital career bridging biology and data. Research the medical coding certification options, including salary prospects and certification pathways, to assess your next steps.

Best Scientists Citing Alan J. Grodzinsky

Trending Scientists

Recently Published Articles