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Biology and Biochemistry

D-Index
94
Citations
29827
World Ranking
2027
National Ranking
1105

Overview

Robert L. Mauck is affiliated with the University of Pennsylvania in the United States. The primary field of study they contribute to is Medicine, with a particular focus on interdisciplinary areas such as Surgery, Rheumatology, Biomedical Engineering, Cell Biology, and Pathology and Forensic Medicine. Their research spans various facets of musculoskeletal health and treatment.

The scientist's recent publications highlight ongoing work in osteoarthritis, cartilage repair, and spine pathology. Notable papers include:

  • Targeting cartilage EGFR pathway for osteoarthritis treatment, 2021, Science Translational Medicine
  • Early changes in cartilage pericellular matrix micromechanobiology portend the onset of post-traumatic osteoarthritis, 2020, Acta Biomaterialia
  • Intervertebral Disc Degeneration Is Associated With Aberrant Endplate Remodeling and Reduced Small Molecule Transport, 2020, Journal of Bone and Mineral Research
  • Fabrication of MSC-laden composites of hyaluronic acid hydrogels reinforced with MEW scaffolds for cartilage repair, 2021, Biofabrication
  • Metabolic Labeling to Probe the Spatiotemporal Accumulation of Matrix at the Chondrocyte-Hydrogel Interface, 2020, Advanced Functional Materials

The main topics of their work encompass:

  • Osteoarthritis Treatment and Mechanisms
  • Knee injuries and reconstruction techniques
  • Spine and Intervertebral Disc Pathology
  • Tendon Structure and Treatment
  • Cellular Mechanics and Interactions
  • Musculoskeletal pain and rehabilitation
  • 3D Printing in Biomedical Research

Robert L. Mauck frequently publishes in a core set of journals, including:

  • JOR Spine
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Orthopaedic Research®
  • Osteoarthritis and Cartilage
  • Acta Biomaterialia

Collaboration forms a significant part of their scientific output, with frequent co-authors including Sarah E. Gullbrand, Jason A. Burdick, Lin Han, Edward D. Bonnevie, and Harvey E. Smith. These partnerships highlight interdisciplinary connections within musculoskeletal and biomedical engineering research.

Best Publications

  • Functional tissue engineering of articular cartilage through dynamic loading of chondrocyte-seeded agarose gels.

    Robert L. Mauck;Michael A. Soltz;Christopher C. B. Wang;Dennis D. Wong

  • The potential to improve cell infiltration in composite fiber-aligned electrospun scaffolds by the selective removal of sacrificial fibers.

    Brendon M. Baker;Albert O. Gee;Robert B. Metter;Ashwin S. Nathan

  • Chondrogenic differentiation and functional maturation of bovine mesenchymal stem cells in long-term agarose culture.

    R.L. Mauck;X. Yuan;R.S. Tuan

  • Fabrication and characterization of six electrospun poly(alpha-hydroxy ester)-based fibrous scaffolds for tissue engineering applications.

    Wan-Ju Li;James A. Cooper;Robert L. Mauck;Rocky S. Tuan

  • Hydrogel design for cartilage tissue engineering: A case study with hyaluronic acid

    Iris L. Kim;Robert L. Mauck;Jason A. Burdick

  • Tissue engineering for articular cartilage repair--the state of the art.

    Brian Johnstone;Mauro Alini;Magali Cucchiarini;George R. Dodge

  • ENGINEERING CONTROLLABLE ANISOTROPY IN ELECTROSPUN BIODEGRADABLE NANOFIBROUS SCAFFOLDS FOR MUSCULOSKELETAL TISSUE ENGINEERING

    Wan-Ju Li;Robert L. Mauck;James A. Cooper;Xiaoning Yuan

  • Enhanced MSC chondrogenesis following delivery of TGF-β3 from alginate microspheres within hyaluronic acid hydrogels in vitro and in vivo

    Liming Bian;David Y. Zhai;Elena Tous;Reena Rai

  • Hydrogels that mimic developmentally relevant matrix and N-cadherin interactions enhance MSC chondrogenesis

    Liming Bian;Murat Guvendiren;Robert L. Mauck;Jason A. Burdick

  • The Effect of Nanofiber Alignment on the Maturation of Engineered Meniscus Constructs

    Brendon M. Baker;Robert L. Mauck

  • Cartilage tissue engineering: its potential and uses

    Catherine K Kuo;Wan-Ju Li;Robert L Mauck;Rocky S Tuan

  • The role of cell seeding density and nutrient supply for articular cartilage tissue engineering with deformational loading.

    R.L. Mauck;C.C-B. Wang;E.S. Oswald;G.A. Ateshian

  • NANOFIBROUS BIOLOGIC LAMINATES REPLICATE THE FORM AND FUNCTION OF THE ANNULUS FIBROSUS

    Nandan L. Nerurkar;Brendon M. Baker;Sounok Sen;Emily E. Wible

  • Influence of seeding density and dynamic deformational loading on the developing structure/function relationships of chondrocyte-seeded agarose hydrogels.

    Robert L. Mauck;Sara L. Seyhan;Gerard A. Ateshian;Clark T. Hung

  • The influence of hyaluronic acid hydrogel crosslinking density and macromolecular diffusivity on human MSC chondrogenesis and hypertrophy.

    Liming Bian;Chieh Hou;Elena Tous;Reena Rai

  • Material properties in unconfined compression of human nucleus pulposus, injectable hyaluronic acid-based hydrogels and tissue engineering scaffolds.

    Jordan M. Cloyd;Neil R. Malhotra;Lihui Weng;Weiliam Chen

  • N-cadherin adhesive interactions modulate matrix mechanosensing and fate commitment of mesenchymal stem cells

    Brian D. Cosgrove;Brian D. Cosgrove;Keeley L. Mui;Tristan P. Driscoll;Tristan P. Driscoll;Steven R. Caliari

  • Coculture of Human Mesenchymal Stem Cells and Articular Chondrocytes Reduces Hypertrophy and Enhances Functional Properties of Engineered Cartilage

    Liming Bian;David Y. Zhai;Robert L. Mauck;Jason A. Burdick

  • Mechanical design criteria for intervertebral disc tissue engineering.

    Nandan L. Nerurkar;Dawn M. Elliott;Robert L. Mauck

  • A Paradigm for Functional Tissue Engineering of Articular Cartilage via Applied Physiologic Deformational Loading

    Clark T. Hung;Robert L. Mauck;Christopher C.-B. Wang;Eric G. Lima

Frequent Co-Authors

Jason A. Burdick
Jason A. Burdick University of Colorado Boulder
Dawn M. Elliott
Dawn M. Elliott University of Delaware
Gerard A. Ateshian
Gerard A. Ateshian Columbia University
Rocky S. Tuan
Rocky S. Tuan Chinese University of Hong Kong
Louis J. Soslowsky
Louis J. Soslowsky University of Pennsylvania
Clark T. Hung
Clark T. Hung Columbia University
Mauro Alini
Mauro Alini AO Foundation
Daisuke Sakai
Daisuke Sakai Tokai University
Liming Bian
Liming Bian South China University of Technology
Vivek B. Shenoy
Vivek B. Shenoy University of Pennsylvania

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