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D-Index & Metrics

Chemistry

D-Index
49
Citations
6308
World Ranking
15024
National Ranking
3827

Research.com Recognitions

  • 2010 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Steven E. Rokita is affiliated with Johns Hopkins University in the United States and has a research focus primarily within the field of Biochemistry, Genetics, and Molecular Biology. Their work spans multiple subfields including Molecular Biology, Organic Chemistry, Materials Chemistry, Health, Toxicology and Mutagenesis, as well as Pediatrics, Perinatology, and Child Health.

The scientist's research topics cover a range of biochemical and molecular biology themes. Key areas include:

  • Porphyrin Metabolism and Disorders
  • Synthesis of Indole Derivatives
  • Enzyme Structure and Function
  • Chemical Analysis and Environmental Impact
  • Neonatal Health and Biochemistry
  • Polyamine Metabolism and Applications
  • RNA Interference and Gene Delivery

Steven E. Rokita has contributed to several publications, with recent notable papers including:

  • "The minimal structure for iodotyrosine deiodinase function is defined by an outlier protein from the thermophilic bacterium Thermotoga neapolitana" (2021) in Journal of Biological Chemistry
  • "Migratory ability of quinone methide-generating acridine conjugates in DNA" (2020) in Organic & Biomolecular Chemistry
  • "Directing Quinone Methide-Dependent Alkylation and Cross-Linking of Nucleic Acids with Quaternary Amines" (2020) in Bioconjugate Chemistry
  • "Substrate Electronics Dominate the Rate of Reductive Dehalogenation Promoted by the Flavin-Dependent Iodotyrosine Deiodinase" (2023) in Biochemistry
  • "Sequence Conservation Does Not Always Signify a Functional Imperative as Observed in the Nitroreductase Superfamily" (2022) in Biochemistry

Their frequent co-authors include Bing Xu, Anton Kozyryev, Zuodong Sun, Daniel Lemen, and Ravina Moirangthem, reflecting collaboration across related biochemical and chemical research efforts.

Publications appear most frequently in the journal Biochemistry, followed by contributions to ACS Chemical Biology, Journal of Biological Chemistry, Nucleic Acids Research, and Organic & Biomolecular Chemistry.

Steven E. Rokita was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2010. This distinction indicates involvement and acknowledgment within the broader scientific community.

Best Publications

  • Substituents on quinone methides strongly modulate formation and stability of their nucleophilic adducts.

    Emily E. Weinert;Ruggero Dondi;Stefano Colloredo-Melz;Kristen N. Frankenfield

  • RECOGNITION OF GUANINE STRUCTURE IN NUCLEIC ACIDS BY NICKEL COMPLEXES

    Cynthia J. Burrows;Steven E. Rokita

  • Targeted strand scission of DNA substrates by a tricopper(II) coordination complex.

    Kristi J. Humphreys;Kenneth D. Karlin;Steven E. Rokita

  • Efficient and specific strand scission of DNA by a dinuclear copper complex: comparative reactivity of complexes with linked tris(2-pyridylmethyl)amine moieties.

    Kristi J. Humphreys;Kenneth D. Karlin;Steven E. Rokita

  • Alkylation of Nucleic Acids by a Model Quinone Methide

    Praveen Pande;Jason Shearer;Jianhong Yang;William A. Greenberg

  • Selective DNA strand scission with binuclear copper complexes: implications for an active Cu2-O2 species.

    Sunita Thyagarajan;Narasimha N. Murthy;Amy A. Narducci Sarjeant;Kenneth D. Karlin

  • DNA and RNA Modification Promoted by [Co(H2O)6]Cl2 and KHSO5: Guanine Selectivity, Temperature Dependence, and Mechanism

    James G. Muller;Ping Zheng;Steven E. Rokita;Cynthia J. Burrows

  • Changing selectivity of DNA oxidation from deoxyribose to Guanine by ligand design and a new binuclear copper complex.

    Lei Li;Kenneth D. Karlin;Steven E. Rokita

  • Ligand effects associated with the intrinsic selectivity of DNA oxidation promoted by nickel(II) macrocyclic complexes

    James G. Muller;Xiaoying Chen;Adonis C. Dadiz;Steven E. Rokita

  • Oxidative strand scission of nucleic acids by a multinuclear copper(II) complex.

    Kristi J. Humphreys;Anne E. Johnson;Kenneth D. Karlin;Steven E. Rokita

  • Nickel(III)‐Promoted DNA Cleavage with Ambient Dioxygen

    Chien Chung Cheng;Steven E. Rokita;Cynthia J. Burrows

  • FORMATION OF DNA ADDUCTS USING NICKEL(II) COMPLEXES OF REDOX-ACTIVE LIGANDS : A COMPARISON OF SALEN AND PEPTIDE COMPLEXES

    James G. Muller;Lou Anne Kayser;Sari J. Paikoff;Victor Duarte

  • Thermodynamic versus kinetic products of DNA alkylation as modeled by reaction of deoxyadenosine.

    Willem F. Veldhuyzen;Anthony J. Shallop;Roger A. Jones;Steven E. Rokita

  • Excess Electron Transfer from an Internally Conjugated Aromatic Amine to 5-Bromo-2‘-deoxyuridine in DNA

    Takeo Ito;Steven E Rokita

  • A transient product of DNA alkylation can be stabilized by binding localization.

    Willem F. Veldhuyzen;Praveen Pande;Steven E. Rokita

  • Criteria for efficient transport of excess electrons in DNA.

    Takeo Ito;Steven E. Rokita

  • Self-repair of thymine dimer in duplex DNA.

    Matthew Ray Holman;Takeo Ito;Steven E Rokita

  • Recognition and strand scission at junctions between single- and double-stranded DNA by a trinuclear copper complex.

    Kristi J. Humphreys;Kenneth D. Karlin;Steven E. Rokita

  • A general strategy for target-promoted alkylation in biological systems

    Qibing Zhou;Steven E. Rokita

  • DNA modification: Intrinsic selectivity of nickel(II) complexes

    Xiaoying Chen;Steven E. Rokita;Cynthia J. Burrows

Frequent Co-Authors

Cynthia J. Burrows
Cynthia J. Burrows University of Utah
Kenneth D. Karlin
Kenneth D. Karlin Johns Hopkins University
Sarah A. Woodson
Sarah A. Woodson Johns Hopkins University
Christopher T. Walsh
Christopher T. Walsh Stanford University
Joshua Telser
Joshua Telser Roosevelt University
David P. Ballou
David P. Ballou University of Michigan–Ann Arbor
Debra A. Kendall
Debra A. Kendall University of Connecticut
Mauro Freccero
Mauro Freccero University of Pavia
Neil V. Blough
Neil V. Blough University of Maryland, College Park
Xiang Zhou
Xiang Zhou Wuhan University

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