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Hiroshi Sugiyama

Hiroshi Sugiyama

D-Index & Metrics

Chemistry

D-Index
89
Citations
29262
World Ranking
2159
National Ranking
116

Biology and Biochemistry

D-Index
89
Citations
30151
World Ranking
2543
National Ranking
158

Overview

Hiroshi Sugiyama is affiliated with Kyoto University in Japan and has an extensive research portfolio within the field of Biochemistry, Genetics and Molecular Biology. Their work spans 309 publications, with a significant focus on Molecular Biology, which accounts for 290 of these. Other notable subfields include Oncology, Biomedical Engineering, Organic Chemistry, and Genetics.

The core research topics addressed by Sugiyama include:

  • Advanced biosensing and bioanalysis techniques
  • RNA Interference and Gene Delivery
  • DNA and Nucleic Acid Chemistry
  • RNA and protein synthesis mechanisms
  • RNA modifications and cancer
  • Epigenetics and DNA Methylation
  • RNA Research and Splicing

Sugiyama has contributed to numerous publications in well-known journals, with frequent appearances in the following venues:

  • ChemBioChem
  • Chemical Communications
  • Nucleic Acids Research
  • Chemistry - A European Journal
  • SSRN Electronic Journal

Some of the recent papers authored or co-authored by Sugiyama include:

  • "N 1-Methylpseudouridine substitution enhances the performance of synthetic mRNA switches in cells" (2020), published in Nucleic Acids Research
  • "CGG repeat RNA G-quadruplexes interact with FMRpolyG to cause neuronal dysfunction in fragile X-related tremor/ataxia syndrome" (2021), published in Science Advances
  • "DNA Nanostructures for Targeted Antimicrobial Delivery" (2020), published in Angewandte Chemie International Edition
  • "Isothermal self-assembly of multicomponent and evolutive DNA nanostructures" (2023), published in Nature Nanotechnology
  • "Artificial intelligence in microbial natural product drug discovery: current and emerging role" (2022), published in Natural Product Reports

The scientist collaborates frequently with several co-authors, including:

  • Masayuki Endo (37 publications)
  • Toshikazu Bando (28 publications)
  • Ganesh N. Pandian (26 publications)
  • Soyoung Park (22 publications)
  • Kaori Hashiya (18 publications)

Best Publications

  • Theoretical Studies of GG-Specific Photocleavage of DNA via Electron Transfer: Significant Lowering of Ionization Potential and 5‘-Localization of HOMO of Stacked GG Bases in B-Form DNA

    Hiroshi Sugiyama;Isao Saito

  • Photoinduced DNA Cleavage via Electron Transfer: Demonstration That Guanine Residues Located 5' to Guanine Are the Most Electron-Donating Sites

    Isao Saito;Masami Takayama;Hiroshi Sugiyama;Kazuhiko Nakatani

  • Mapping of the Hot Spots for DNA Damage by One-Electron Oxidation: Efficacy of GG Doublets and GGG Triplets as a Trap in Long-Range Hole Migration

    Isao Saito;Takashi Nakamura;Kazuhiko Nakatani;Yasunori Yoshioka

  • The new models of the human telomere d[AGGG(TTAGGG)3] in K+ solution.

    Yan Xu;Yuki Noguchi;Hiroshi Sugiyama

  • A DNA-based molecular motor that can navigate a network of tracks

    Shelley F. J. Wickham;Jonathan Bath;Yousuke Katsuda;Masayuki Endo

  • Oligomeric procyanidins in apple polyphenol are main active components for inhibition of pancreatic lipase and triglyceride absorption.

    Hiroshi Sugiyama;Yoko Akazome;Toshihiko Shoji;Atsuko Yamaguchi

  • Direct observation of stepwise movement of a synthetic molecular transporter

    Shelley F. J. Wickham;Masayuki Endo;Yousuke Katsuda;Kumi Hidaka

  • Recent Progress of Targeted G-Quadruplex-Preferred Ligands Toward Cancer Therapy

    Sefan Asamitsu;Shunsuke Obata;Zutao Yu;Toshikazu Bando

  • A light-driven three-dimensional plasmonic nanosystem that translates molecular motion into reversible chiroptical function

    Anton Kuzyk;Yangyang Yang;Xiaoyang Duan;Xiaoyang Duan;Simon Stoll;Simon Stoll

  • The C-kit receptor-mediated signal transduction and tumor-related diseases.

    Jing Liang;Yan-Ling Wu;Bing-Jia Chen;Wen Zhang

  • RNA-DNA Triplex Formation by Long Noncoding RNAs

    Yue Li;Junetha Syed;Hiroshi Sugiyama

  • Formation of the G-quadruplex and i-motif structures in retinoblastoma susceptibility genes (Rb).

    Yan Xu;Hiroshi Sugiyama

  • (P)-helicene displays chiral selection in binding to Z-DNA.

    Yan Xu;You Xin Zhang;Hiroshi Sugiyama;Tomoko Umano

  • A chiral wedge molecule inhibits telomerase activity.

    Ken-ichi Shinohara;Yuta Sannohe;Shuji Kaieda;Ken-ichi Tanaka

  • A single-molecule platform for investigation of interactions between G-quadruplexes and small-molecule ligands

    Deepak Koirala;Soma Dhakal;Beth Ashbridge;Yuta Sannohe

  • Single-molecule analysis using DNA origami.

    Arivazhagan Rajendran;Masayuki Endo;Hiroshi Sugiyama

  • Possible cause of G-C-->C-G transversion mutation by guanine oxidation product, imidazolone.

    Katsuhito Kino;Hiroshi Sugiyama

  • 13 C nuclear magnetic resonance spectra of glucobioses, glucotrioses, and glucans

    Taichi Usui;Naotaka Yamaoka;Kazuo Matsuda;Katura Tuzimura

  • Lipid-bilayer-assisted two-dimensional self-assembly of DNA origami nanostructures

    Yuki Suzuki;Masayuki Endo;Hiroshi Sugiyama

  • Synthesis and biological properties of sequence-specific DNA-alkylating pyrrole-imidazole polyamides.

    Toshikazu Bando;Hiroshi Sugiyama

  • Visualization of Dynamic Conformational Switching of the G-Quadruplex in a DNA Nanostructure

    Yuta Sannohe;Masayuki Endo;Yousuke Katsuda;Kumi Hidaka

Frequent Co-Authors

Masayuki Endo
Masayuki Endo Kyoto University
Isao Saito
Isao Saito Kyoto University
Souichi Adachi
Souichi Adachi Shiga Prefectural General Hospital
Makiya Nishikawa
Makiya Nishikawa Tokyo University of Science
Sidney M. Hecht
Sidney M. Hecht Arizona State University
Andrew H.-J. Wang
Andrew H.-J. Wang Academia Sinica
Yoshinobu Takakura
Yoshinobu Takakura Kyoto University
Takuya Ueda
Takuya Ueda University of Tokyo
Shosuke Kawanishi
Shosuke Kawanishi Suzuka University of Medical Science
Hiroshi Fukuda
Hiroshi Fukuda Tohoku University

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