World's Best Scientists 2026 revealed!

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Chemistry

D-Index
110
Citations
41909
World Ranking
815
National Ranking
325

Biology and Biochemistry

D-Index
112
Citations
55651
World Ranking
884
National Ranking
552

Research.com Recognitions

  • 2019 - Fellow, National Academy of Inventors
  • 2017 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2006 - US President's National Medal of Science "For his fundamental research contributions at the interface of organic chemistry and biology, and for his influence in education and industrial innovation.", Awarded by President George W. Bush in a White House ceremony on July 27, 2007.
  • 1988 - Fellow of the American Academy of Arts and Sciences
  • 1986 - Member of the National Academy of Sciences
  • 1983 - Fellow of John Simon Guggenheim Memorial Foundation
  • 1977 - Fellow of Alfred P. Sloan Foundation

Overview

Peter B. Dervan is affiliated with the California Institute of Technology in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant contributions in molecular biology and genetics subfields.

The scientist's work spans several main topics, including:

  • DNA and Nucleic Acid Chemistry
  • Genomics and Chromatin Dynamics
  • RNA Interference and Gene Delivery
  • Estrogen and related hormone effects
  • Cancer therapeutics and mechanisms
  • RNA and protein synthesis mechanisms

Recent publications by Peter B. Dervan include:

  • Single position substitution of hairpin pyrrole-imidazole polyamides imparts distinct DNA-binding profiles across the human genome, 2020, PLoS ONE
  • Repression of the transcriptional activity of ERRα with sequence-specific DNA-binding polyamides, 2020, Medicinal Chemistry Research
  • Single position substitution of hairpin pyrrole-imidazole polyamides imparts distinct DNA-binding profiles across the human genome, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Issue Information, 2021, Biopolymers

Frequent co-authors in the scientist's work are:

  • Paul B. Finn
  • Devesh Bhimsaria
  • Asfa Ali
  • Asuka Eguchi
  • Aseem Z. Ansari

Peter B. Dervan has published in the following venues multiple times:

  • PLoS ONE
  • Medicinal Chemistry Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biopolymers

The scientist's recognition includes several awards and fellowships, such as:

  • Fellow, National Academy of Inventors (2019)
  • Fellow of the American Association for the Advancement of Science (AAAS) (2017)
  • US President's National Medal of Science (2006), awarded for fundamental research contributions at the interface of organic chemistry and biology, as well as influence in education and industrial innovation
  • Fellow of the American Academy of Arts and Sciences (1988)
  • Member of the National Academy of Sciences (1986)
  • Fellow of John Simon Guggenheim Memorial Foundation (1983)
  • Fellow of Alfred P. Sloan Foundation (1977)

Best Publications

  • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

    Marcy E. MacDonald;Christine M. Ambrose;Mabel P. Duyao;Richard H. Myers

  • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

    M Shah;N Datson;L Srinidhi;VP Stanton

  • Sequence-specific cleavage of double helical DNA by triple helix formation

    Heinz E. Moser;Peter B. Dervan

  • Molecular recognition of DNA by small molecules.

    Peter B. Dervan

  • Design of sequence-specific DNA-binding molecules.

    Peter B. Dervan

  • Recognition of the DNA minor groove by pyrrole-imidazole polyamides.

    Peter B Dervan;Benjamin S Edelson

  • Second structural motif for recognition of DNA by oligonucleotide-directed triple-helix formation

    Peter A. Beal;Peter B. Dervan

  • Recognition of the four Watson–Crick base pairs in the DNA minor groove by synthetic ligands

    Sarah White;Jason W. Szewczyk;James M. Turner;Eldon E. Baird

  • Regulation of gene expression by small molecules

    Joel M. Gottesfeld;Laura Neely;John W. Trauger;Eldon E. Baird

  • Cleavage of DNA with methidiumpropyl-EDTA-iron(II): reaction conditions and product analyses

    Robert P. Hertzberg;Peter B. Dervan

  • Inhibition of DNA binding proteins by oligonucleotide-directed triple helix formation.

    Louis J. Maher;Barbara Wold;Peter B. Dervan

  • Cleavage of double helical DNA by methidium-propyl-EDTA-iron(II)

    Robert P. Hertzberg;Peter B. Dervan

  • Recognition of DNA by designed ligands at subnanomolar concentrations

    John W. Trauger;Eldon E. Baird;Peter B. Dervan

  • Solid Phase Synthesis of Polyamides Containing Imidazole and Pyrrole Amino Acids

    Eldon E. Baird;Peter B. Dervan

  • Map of distamycin, netropsin, and actinomycin binding sites on heterogeneous DNA: DNA cleavage-inhibition patterns with methidiumpropyl-EDTA.Fe(II)

    M W Van Dyke;R P Hertzberg;P B Dervan

  • Sequence-specific DNA recognition by polyamides

    Peter B Dervan;Roland W Bürli

  • Sequence-specific cleavage of single-stranded DNA: oligodeoxynucleotide-EDTA X Fe(II).

    Geoffrey B. Dreyer;Peter B. Dervan

  • A Structural Basis for Recognition of A·T and T·A Base Pairs in the Minor Groove of B-DNA

    Clara L. Kielkopf;Sarah White;Jason W. Szewczyk;James M. Turner

  • Triple helix formation by oligonucleotides on DNA extended to the physiological pH range

    Thomas J. Povsic;Peter B. Dervan

  • Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands.

    Liliane A. Dickinson;Richard J. Gulizia;John W. Trauger;Eldon E. Baird

Frequent Co-Authors

Eldon E. Baird
Eldon E. Baird California Institute of Technology
Joel M. Gottesfeld
Joel M. Gottesfeld Scripps Research Institute
Christian Melander
Christian Melander University of Notre Dame
Milan Mrksich
Milan Mrksich Northwestern University
Aseem Z. Ansari
Aseem Z. Ansari University of Wisconsin–Madison
David E. Wemmer
David E. Wemmer University of California, Berkeley
Peter G. Schultz
Peter G. Schultz Scripps Research Institute
Scott A. Strobel
Scott A. Strobel Yale University
Karolin Luger
Karolin Luger University of Colorado Boulder
Barbara J. Wold
Barbara J. Wold California Institute of Technology

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