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Medicine

D-Index
150
Citations
81351
World Ranking
1161
National Ranking
670

Overview

Christopher A. Ross is affiliated with Johns Hopkins University School of Medicine in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, medicine, and neuroscience.

The scientist's main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine
  • Neuroscience

Subfields of particular focus are:

  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Neurology
  • Radiology, Nuclear Medicine and Imaging
  • Genetics

The major topics covered in their work are:

  • Genetic Neurodegenerative Diseases
  • Mitochondrial Function and Pathology
  • Neurological disorders and treatments
  • Parkinson's Disease Mechanisms and Treatments
  • Muscle Physiology and Disorders
  • Cancer-related gene regulation
  • Ocular Surface and Contact Lens

Frequent publication venues for their work include:

  • Human Molecular Genetics
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Investigative Ophthalmology & Visual Science
  • Brain
  • Nature Communications

Notable recent papers authored or co-authored by Christopher A. Ross include:

  • "Huntington disease: new insights into molecular pathogenesis and therapeutic opportunities," 2020, Nature Reviews Neurology
  • "A biological classification of Huntington's disease: the Integrated Staging System," 2022, The Lancet Neurology
  • "Preventing amyotrophic lateral sclerosis: insights from pre-symptomatic neurodegenerative diseases," 2021, Brain
  • "Amygdala and anterior cingulate transcriptomes from individuals with bipolar disorder reveal downregulated neuroimmune and synaptic pathways," 2022, Nature Neuroscience
  • "TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models," 2020, The EMBO Journal

The scientist frequently collaborates with the following researchers:

  • Tamara Ratovitski
  • Wanli W. Smith
  • Nicolas Arbez
  • Wenzhen Duan
  • Russell L. Margolis

Best Publications

  • FORMATION OF NEURONAL INTRANUCLEAR INCLUSIONS UNDERLIES THE NEUROLOGICAL DYSFUNCTION IN MICE TRANSGENIC FOR THE HD MUTATION

    Stephen W Davies;Mark Turmaine;Barbara A Cozens;Marian DiFiglia

  • Huntington's disease: from molecular pathogenesis to clinical treatment

    Christopher A Ross;Sarah J Tabrizi

  • Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

    Andrew B. West;Darren J. Moore;Saskia Biskup;Artem Bugayenko

  • Trinucleotide repeat length instability and age of onset in Huntington's disease

    M Duyao;C Ambrose;R Myers;A Novelletto

  • Interference by Huntingtin and Atrophin-1 with CBP-Mediated Transcription Leading to Cellular Toxicity

    Frederick C. Nucifora;Masayuki Sasaki;Matthew F. Peters;Hui Huang

  • Tonic vasomotor control by the rostral ventrolateral medulla: effect of electrical or chemical stimulation of the area containing C1 adrenaline neurons on arterial pressure, heart rate, and plasma catecholamines and vasopressin

    Christopher A. Ross;David A. Ruggiero;Dong H. Park;Tong H. Joh

  • TriTrypDB: a functional genomic resource for the Trypanosomatidae

    Martin Aslett;Cristina Aurrecoechea;Matthew Berriman;John Brestelli

  • Huntington disease: natural history, biomarkers and prospects for therapeutics

    Christopher A Ross;Elizabeth Hoppes Aylward;Edward J Wild;Douglas R Langbehn

  • Parkin ubiquitinates the α-synuclein–interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease

    Kenny K.K. Chung;Yi Zhang;Kah Leong Lim;Yuji Tanaka

  • Detection of Huntington’s disease decades before diagnosis: The Predict HD study

    Jane Paulsen;Douglas R Langbehn;Julie C Stout;Elizabeth H Aylward

  • Intranuclear Inclusions and Neuritic Aggregates in Transgenic Mice Expressing a Mutant N-Terminal Fragment of Huntingtin

    Gabriele Schilling;Mark W. Becher;Alan H. Sharp;Hyder A. Jinnah

  • Decreased expression of striatal signaling genes in a mouse model of Huntington’s disease

    Ruth Luthi-Carter;Andrew Strand;Nikki L. Peters;Steven M. Solano

  • Opinion: What is the role of protein aggregation in neurodegeneration?

    Christopher A. Ross;Michelle A. Poirier

  • A huntingtin-associated protein enriched in brain with implications for pathology

    Xiao-Jiang Li;Shi-Hua Li;Alan H. Sharp;Frederick C. Nucifora

  • Kinase activity of mutant LRRK2 mediates neuronal toxicity.

    Wanli W Smith;Zhong Pei;Haibing Jiang;Valina L Dawson

  • Caspase Cleavage of Gene Products Associated with Triplet Expansion Disorders Generates Truncated Fragments Containing the Polyglutamine Tract

    Cheryl L. Wellington;Lisa M. Ellerby;Abigail S. Hackam;Russell L. Margolis

  • Endothelin in brain: receptors, mitogenesis, and biosynthesis in glial cells

    Mathew W. Maccumber;Christopher A. Ross;Solomon H. Snyder

  • A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development.

    Atsushi Kamiya;Atsushi Kamiya;Ken Ichiro Kubo;Toshifumi Tomoda;Toshifumi Tomoda;Manabu Takaki

  • Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1 : implications for Lewy body formation

    Kah Leong Lim;Katherine C. M. Chew;Jeanne M. M. Tan;Cheng Wang

  • Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions.

    Simone Engelender;Zachary Kaminsky;Xin Guo;Alan H. Sharp

Frequent Co-Authors

Russell L. Margolis
Russell L. Margolis Johns Hopkins University School of Medicine
Elizabeth Aylward
Elizabeth Aylward Seattle Children's Hospital
Jane S. Paulsen
Jane S. Paulsen University of Wisconsin–Madison
Michael R. Hayden
Michael R. Hayden University of British Columbia
Peter C.M. van Zijl
Peter C.M. van Zijl Kennedy Krieger Institute
Akira Sawa
Akira Sawa Johns Hopkins University
Solomon H. Snyder
Solomon H. Snyder Johns Hopkins University School of Medicine
Alan H. Sharp
Alan H. Sharp Johns Hopkins University School of Medicine
Susumu Mori
Susumu Mori Johns Hopkins University School of Medicine
Melvin G. McInnis
Melvin G. McInnis University of Michigan–Ann Arbor

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