What is he best known for?
The fields of study he is best known for:
Xiao-Jiang Li focuses on Huntingtin, Huntington's disease, Huntingtin Protein, Molecular biology and Neurodegeneration.
His Huntingtin research includes themes of Neuron and Cell biology.
His Huntington's disease study integrates concerns from other disciplines, such as Neuropathology, Anatomy, Neuropil, Neuroscience and Degenerative disease.
His Huntingtin Protein research is multidisciplinary, incorporating perspectives in Genetically modified mouse, Transgene, Gliosis and Glial fibrillary acidic protein.
His studies in Molecular biology integrate themes in fields like Neurotoxicity, Immunoprecipitation, Glutamate receptor, Excitotoxicity and HEK 293 cells.
His Mutant research is multidisciplinary, incorporating elements of Mutation and Cell nucleus.
His most cited work include:
- A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration. (749 citations)
- Nuclear and Neuropil Aggregates in Huntington’s Disease: Relationship to Neuropathology (738 citations)
- Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease (639 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of investigation include Huntingtin, Cell biology, Neurodegeneration, Mutant and Molecular biology.
As part of his Huntington's disease and Genetics and Huntingtin studies, he is studying Huntingtin.
The various areas that he examines in his Huntington's disease study include Neuropil and Neuropathology.
His work deals with themes such as Neurotoxicity, Neurite and Biochemistry, which intersect with Cell biology.
Xiao-Jiang Li combines subjects such as Neuroscience, Transgene, Pathogenesis and Proteasome with his study of Neurodegeneration.
The concepts of his Molecular biology study are interwoven with issues in Immunoprecipitation, Transcription factor, HEK 293 cells, Promoter and Regulation of gene expression.
He most often published in these fields:
- Huntingtin (59.31%)
- Cell biology (45.45%)
- Neurodegeneration (49.35%)
What were the highlights of his more recent work (between 2018-2021)?
- Neurodegeneration (49.35%)
- Cell biology (45.45%)
- Mutant (35.50%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Neurodegeneration, Cell biology, Mutant, Neuroscience and CRISPR.
His Neurodegeneration research includes themes of Neuropathology and Primate.
Xiao-Jiang Li has included themes like Huntingtin and Retinal ganglion cell, Retina in his Cell biology study.
His Huntingtin study necessitates a more in-depth grasp of Huntington's disease.
His Mutant research incorporates themes from Neurotoxicity, Transgene, Decussation, Zebrafish and Spinocerebellar ataxia.
The study incorporates disciplines such as Autism and Autism spectrum disorder in addition to Neuroscience.
Between 2018 and 2021, his most popular works were:
- CRISPR/Cas9-mediated PINK1 deletion leads to neurodegeneration in rhesus monkeys (21 citations)
- CRISPR/Cas9-mediated PINK1 deletion leads to neurodegeneration in rhesus monkeys (21 citations)
- CRISPR/Cas9-mediated disruption of SHANK3 in monkey leads to drug-treatable autism-like symptoms. (15 citations)
In his most recent research, the most cited papers focused on:
His primary scientific interests are in Neurodegeneration, CRISPR, Neuroscience, Autism spectrum disorder and Autism.
The Neurodegeneration study combines topics in areas such as Genome editing, Computational biology, PINK1 and Cell biology.
His CRISPR study integrates concerns from other disciplines, such as Mutation, SHANK3 Gene, Scaffold protein, Fluoxetine and Antidepressant.
His study in Neuroscience is interdisciplinary in nature, drawing from both Offspring and Pregnancy.
In most of his Autism spectrum disorder studies, his work intersects topics such as Cerebellum.
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