World's Best Scientists 2026 revealed!
Marcy E. MacDonald

Marcy E. MacDonald

Award Badge
Best Female Scientists
2025

D-Index & Metrics

Best Female Scientists

D-Index
114
Citations
63364
World Ranking
728
National Ranking
440

Genetics

D-Index
115
Citations
64647
World Ranking
450
National Ranking
229

Medicine

D-Index
115
Citations
65193
World Ranking
4457
National Ranking
2429

Neuroscience

D-Index
115
Citations
65056
World Ranking
446
National Ranking
262

Marcy E. MacDonald publication distribution in Neuroscience in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Neuroscience in 2026. The highlighted bar marks where Marcy E. MacDonald sits on this spectrum.

38–47 publications: 18 scientists 48–57 publications: 79 scientists 58–67 publications: 193 scientists 68–77 publications: 323 scientists 78–87 publications: 406 scientists 88–97 publications: 452 scientists 98–107 publications: 539 scientists 108–117 publications: 505 scientists 118–127 publications: 522 scientists 128–137 publications: 469 scientists 138–147 publications: 456 scientists 148–157 publications: 459 scientists 158–167 publications: 397 scientists 168–177 publications: 383 scientists 178–187 publications: 350 scientists 188–197 publications: 302 scientists 198–207 publications: 306 scientists 208–217 publications: 262 scientists 218–227 publications: 242 scientists 228–237 publications: 220 scientists 238–247 publications: 203 scientists 248–257 publications: 174 scientists 258–267 publications: 176 scientists 268–277 publications: 175 scientists 278–287 publications: 125 scientists 288–297 publications: 116 scientists 298–307 publications: 127 scientists 308–317 publications: 128 scientists 318–327 publications: 99 scientists 328–337 publications: 89 scientists 338–347 publications: 78 scientists 348–357 publications: 96 scientists 358–367 publications: 66 scientists 368–377 publications: 59 scientists 378–387 publications: 65 scientists 388–397 publications: 54 scientists 398–407 publications: 48 scientists 408–417 publications: 49 scientists 418–427 publications: 34 scientists 428–437 publications: 31 scientists 438–447 publications: 30 scientists 448–457 publications: 31 scientists 458–467 publications: 36 scientists 468–477 publications: 40 scientists 478–487 publications: 35 scientists 488–497 publications: 30 scientists 498–507 publications: 23 scientists 508–517 publications: 26 scientists 518–527 publications: 20 scientists 528–537 publications: 23 scientists 538–547 publications: 20 scientists 548–557 publications: 20 scientists 558–567 publications: 17 scientists 568–577 publications: 14 scientists 578–587 publications: 20 scientists 588–597 publications: 20 scientists 598–607 publications: 19 scientists 608–617 publications: 18 scientists 618–627 publications: 17 scientists 628–637 publications: 11 scientists 638–647 publications: 11 scientists 648–657 publications: 11 scientists 658–667 publications: 8 scientists 668–677 publications: 7 scientists 678–687 publications: 11 scientists 688–697 publications: 10 scientists 698–707 publications: 4 scientists 708–717 publications: 6 scientists 718–727 publications: 5 scientists 728–737 publications: 5 scientists 738–747 publications: 9 scientists 748–757 publications: 9 scientists 758–767 publications: 3 scientists 768–777 publications: 7 scientists 778–787 publications: 7 scientists 788–797 publications: 6 scientists 798–807 publications: 2 scientists 808–817 publications: 2 scientists 818–827 publications: 7 scientists 828–837 publications: 0 scientists 838–847 publications: 9 scientists 848–857 publications: 3 scientists 858–867 publications: 1 scientists 868–877 publications: 3 scientists 878–886 publications: 6 scientists 887+ publications: 100 scientists
38 publications 887+

This scientist: 347 publications — 87th percentile

87% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 887 publications or more.

Marcy E. MacDonald D-index placement in Neuroscience in 2026

The chart shows the D-index (discipline H-index) distribution of Neuroscience scientists ranked by Research.com in 2026. The highlighted bar marks where Marcy E. MacDonald sits on this spectrum.

30–31 D-Index: 42 scientists 32–33 D-Index: 172 scientists 34–35 D-Index: 296 scientists 36–37 D-Index: 435 scientists 38–39 D-Index: 459 scientists 40–41 D-Index: 456 scientists 42–43 D-Index: 467 scientists 44–45 D-Index: 478 scientists 46–47 D-Index: 512 scientists 48–49 D-Index: 435 scientists 50–51 D-Index: 425 scientists 52–53 D-Index: 418 scientists 54–55 D-Index: 392 scientists 56–57 D-Index: 357 scientists 58–59 D-Index: 334 scientists 60–61 D-Index: 328 scientists 62–63 D-Index: 260 scientists 64–65 D-Index: 278 scientists 66–67 D-Index: 239 scientists 68–69 D-Index: 250 scientists 70–71 D-Index: 210 scientists 72–73 D-Index: 200 scientists 74–75 D-Index: 189 scientists 76–77 D-Index: 170 scientists 78–79 D-Index: 146 scientists 80–81 D-Index: 113 scientists 82–83 D-Index: 126 scientists 84–85 D-Index: 100 scientists 86–87 D-Index: 84 scientists 88–89 D-Index: 99 scientists 90–91 D-Index: 84 scientists 92–93 D-Index: 85 scientists 94–95 D-Index: 72 scientists 96–97 D-Index: 76 scientists 98–99 D-Index: 45 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 43 scientists 104–105 D-Index: 32 scientists 106–107 D-Index: 45 scientists 108–109 D-Index: 50 scientists 110–111 D-Index: 32 scientists 112–113 D-Index: 39 scientists 114–115 D-Index: 32 scientists 116–117 D-Index: 29 scientists 118–119 D-Index: 27 scientists 120–121 D-Index: 19 scientists 122–123 D-Index: 23 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 16 scientists 128–129 D-Index: 24 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 21 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 14 scientists 138–139 D-Index: 15 scientists 140–141 D-Index: 10 scientists 142–143 D-Index: 10 scientists 144–145 D-Index: 13 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 8 scientists 150–151 D-Index: 6 scientists 152–153 D-Index: 6 scientists 154–155 D-Index: 7 scientists 156–157 D-Index: 7 scientists 158–159 D-Index: 10 scientists 160–161 D-Index: 4 scientists 162 D-Index: 8 scientists 163+ D-Index: 100 scientists
30 D-Index 163+

This scientist: 115 D-Index — 95th percentile

95% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 163 D-Index or more.

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award

Overview

Marcy E. MacDonald is affiliated with Harvard University in the United States, focusing primarily on research related to genetic neurodegenerative diseases. Their work spans several interconnected fields within biochemistry, genetics, molecular biology, and neuroscience, with a particular concentration on molecular biology and cellular and molecular neuroscience subfields.

The topics of their research include genetic neurodegenerative diseases, mitochondrial function and pathology, ubiquitin and proteasome pathways, neurological disorders and treatments, DNA repair mechanisms, muscle physiology and disorders, and RNA research and splicing.

Marcy E. MacDonald has contributed to notable papers, including:

  • "Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington's disease knock-in mice is blocked by Mlh1 knock-out," 2020, Human Molecular Genetics
  • "Genetic and Functional Analyses Point to FAN1 as the Source of Multiple Huntington Disease Modifier Effects," 2020, The American Journal of Human Genetics
  • "Genetic modifiers of somatic expansion and clinical phenotypes in Huntington's disease highlight shared and tissue-specific effects," 2025, Nature Genetics
  • "A Multi-Omic Huntington's Disease Transgenic Sheep-Model Database for Investigating Disease Pathogenesis," 2021, Journal of Huntington s Disease
  • "Posttranscriptional regulation of FAN1 by miR-124-3p at rs3512 underlies onset-delaying genetic modification in Huntington's disease," 2024, Proceedings of the National Academy of Sciences

Their frequent coauthors have included James F. Gusella, Jong-Min Lee, Tammy Gillis, Seung Kwak, and Kyung-Hee Kim.

Marcy E. MacDonald has published works in several venues, most frequently in bioRxiv (Cold Spring Harbor Laboratory), along with publications in Human Molecular Genetics, The American Journal of Human Genetics, Nature Genetics, and Proceedings of the National Academy of Sciences.

Best Publications

  • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

    Marcy E. MacDonald;Christine M. Ambrose;Mabel P. Duyao;Richard H. Myers

  • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

    M Shah;N Datson;L Srinidhi;VP Stanton

  • Homozygous Defect in HIV-1 Coreceptor Accounts for Resistance of Some Multiply-Exposed Individuals to HIV-1 Infection

    Rong Liu;William A Paxton;Sunny Choe;Daniel Ceradini

  • Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

    Bin Zhang;Chris Gaiteri;Liviu Gabriel Bodea;Zhi Wang

  • A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor

    James A. Trofatter;Mia M. MacCollin;Joni L. Rutter;Jill R. Murrell

  • Loss of Huntingtin-Mediated BDNF Gene Transcription in Huntington's Disease

    Chiara Zuccato;Andrea Ciammola;Dorotea Rigamonti;Blair R. Leavitt

  • Huntingtin Controls Neurotrophic Support and Survival of Neurons by Enhancing BDNF Vesicular Transport along Microtubules

    Laurent R Gauthier;Bénédicte C Charrin;Maria Borrell-Pagès;Jim P Dompierre

  • Trinucleotide repeat length instability and age of onset in Huntington's disease

    M Duyao;C Ambrose;R Myers;A Novelletto

  • Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset

    Nancy S. Wexler;Judith Lorimer;Julie Porter;Fidela Gomez

  • Inactivation of the mouse Huntington's disease gene homolog Hdh.

    Mabel P. Duyao;Anna B. Auerbach;Angela Ryan;Francesca Persichetti

  • Detection of Huntington’s disease decades before diagnosis: The Predict HD study

    Jane Paulsen;Douglas R Langbehn;Julie C Stout;Elizabeth H Aylward

  • Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease

    Russell G. Snell;John C. MacMillan;Jeremy Peter Cheadle;Iain Fenton

  • CAG repeat number governs the development rate of pathology in Huntington's disease

    John B. Penney;Jean‐Paul Vonsattel;Marcy E. Macdonald;James F. Gusella

  • Disruption of Neurexin 1 Associated with Autism Spectrum Disorder

    Hyung Goo Kim;Shotaro Kishikawa;Anne W. Higgins;Ihn Sik Seong

  • Dominant phenotypes produced by the HD mutation in STHdhQ111 striatal cells

    Flavia Trettel;Dorotea Rigamonti;Paige Hilditch-Maguire;Vanessa C. Wheeler

  • Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion.

    Jacqueline K. White;Wojtek Auerbach;Mabel P. Duyao;Jean-Paul Vonsattel

  • Polyglutamine-Expanded Human Huntingtin Transgenes Induce Degeneration of Drosophila Photoreceptor Neurons

    George R Jackson;Iris Salecker;Xinzhong Dong;Xiang Yao

  • Induced Pluripotent Stem Cells from Patients with Huntington’s Disease : Show CAG Repeat-Expansion-Associated Phenotypes

    Virginia B. Mattis;Soshana P. Svendsen;Allison Ebert;Clive N. Svendsen

  • Identification of Genetic Factors that Modify Clinical Onset of Huntington’s Disease

    Jong-Min Lee;Vanessa C. Wheeler;Michael J. Chao;Jean Paul G. Vonsattel

  • Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release

    Yeun Su Choo;Gail V.W. Johnson;Marcy MacDonald;Peter J. Detloff

  • Molecular genetics: unmasking polyglutamine triggers in neurodegenerative disease.

    James F. Gusella;Marcy E. MacDonald

Frequent Co-Authors

James F. Gusella
James F. Gusella Harvard University
Richard H. Myers
Richard H. Myers Boston University
John J. Wasmuth
John J. Wasmuth University of California, Irvine
Gillian P. Bates
Gillian P. Bates University College London
Christopher A. Ross
Christopher A. Ross Johns Hopkins University School of Medicine
Christine Ambrose
Christine Ambrose Biogen (United States)
Michael R. Hayden
Michael R. Hayden University of British Columbia
Jane S. Paulsen
Jane S. Paulsen University of Wisconsin–Madison
Andrea Novelletto
Andrea Novelletto University of Rome Tor Vergata
Michael Orth
Michael Orth University of Ulm

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Genetics often leads students to consider diverse healthcare fields that blend science with patient care. Many career pathways are available through online learning, offering flexibility for working professionals and students alike.

For those interested in advanced clinical practice, pursuing a nurse practitioner degree online can open doors to specialized roles and increased responsibilities. If you’re starting your journey in healthcare, researching the best online nursing programs is a great way to compare options that fit your goals and budget.

Nurses aiming for leadership or research-focused positions may find value in the cheapest dnp online programs, which prepare graduates for top-tier roles in healthcare innovation and administration. Meanwhile, registered nurses seeking to advance can benefit from enrolling in the best online rn to bsn programs.

Together, these online degrees support a variety of genetics-related careers, from clinical practice to healthcare leadership, expanding your opportunities in the ever-evolving field of life and health sciences.

Best Scientists Citing Marcy E. MacDonald

Trending Scientists

Recently Published Articles