What is she best known for?
The fields of study she is best known for:
The scientist’s investigation covers issues in Genetics, Huntington's disease, Huntingtin, Huntingtin Protein and Trinucleotide repeat expansion.
Her work on Genetics deals in particular with Allele, Mutation, Gene, Exon and Chromosome.
Her Huntington's disease research is multidisciplinary, relying on both Striatum, Endocrinology and Degenerative disease.
Her work carried out in the field of Huntingtin brings together such families of science as Molecular biology, Mutant protein and Cell biology.
Her Huntingtin Protein study combines topics from a wide range of disciplines, such as RE1-silencing transcription factor, Transgene, Neurotrophic factors, Neurotrophin and Endoplasmic reticulum.
The various areas that Marcy E. MacDonald examines in her Trinucleotide repeat expansion study include Fragile X syndrome, Lymphoblast, Phenotype, Somatic cell and Locus.
Her most cited work include:
- A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes (6485 citations)
- A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group. (2979 citations)
- Homozygous Defect in HIV-1 Coreceptor Accounts for Resistance of Some Multiply-Exposed Individuals to HIV-1 Infection (2813 citations)
What are the main themes of her work throughout her whole career to date?
Her main research concerns Genetics, Huntington's disease, Huntingtin, Gene and Trinucleotide repeat expansion.
Her Genetics study typically links adjacent topics like Molecular biology.
Her Huntington's disease study incorporates themes from Phenotype, Neuroscience, Neurodegeneration and Age of onset.
Her Huntingtin research is multidisciplinary, incorporating elements of SETD2 and Cell biology.
Her Trinucleotide repeat expansion study combines topics in areas such as Single-nucleotide polymorphism, Genetic association, Genetic variation and DNA repair.
Her Allele research is multidisciplinary, relying on both Chromosome and Genotype.
She most often published in these fields:
- Genetics (68.41%)
- Huntington's disease (53.02%)
- Huntingtin (31.32%)
What were the highlights of her more recent work (between 2016-2021)?
- Huntington's disease (53.02%)
- Genetics (68.41%)
- Trinucleotide repeat expansion (28.85%)
In recent papers she was focusing on the following fields of study:
Her scientific interests lie mostly in Huntington's disease, Genetics, Trinucleotide repeat expansion, Gene and Huntingtin.
Her research on Huntington's disease concerns the broader Disease.
Her research in Trinucleotide repeat expansion intersects with topics in Gene knockin, Genetic variation and DNA repair.
Her work in the fields of Gene, such as Phenotype, Exon, Exome sequencing and Gene expression, intersects with other areas such as FAN1.
Marcy E. MacDonald has researched Huntingtin in several fields, including Neuropathology, Neurodegeneration and Human brain.
Marcy E. MacDonald combines subjects such as Huntingtin Protein, Mutant, Polyglutamine tract and Genotype with her study of Mutation.
Between 2016 and 2021, her most popular works were:
- CAG repeat not polyglutamine length determines timing of Huntington’s disease onset (133 citations)
- Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice (128 citations)
- A modifier of Huntington's disease onset at the MLH1 locus. (48 citations)
In her most recent research, the most cited papers focused on:
Marcy E. MacDonald mostly deals with Huntington's disease, Genetics, Trinucleotide repeat expansion, Allele and Huntingtin.
Her Huntington's disease research incorporates themes from Neuroscience, Phenotype, Gene, Neurodegeneration and Computational biology.
Her Genetics study is mostly concerned with Locus and Genome-wide association study.
Her Allele research focuses on Mutation and how it connects with Subclinical infection, Genotype, Chromosome, Putamen and Chromosome 15.
Her study in the field of Huntingtin Protein is also linked to topics like Urea transporter.
Marcy E. MacDonald has included themes like Neuropathology, Endocrinology and Age of onset in her Huntingtin Protein study.
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