What is he best known for?
The fields of study he is best known for:
- Gene
- Enzyme
- Internal medicine
His primary scientific interests are in Immunology, Adenosine deaminase, Adenosine deaminase deficiency, Adenosine and Deoxyadenosine.
His work carried out in the field of Immunology brings together such families of science as Genetic enhancement, Severe combined immunodeficiency and Enzyme replacement therapy.
His Adenosine deaminase research is under the purview of Endocrinology.
He has researched Adenosine deaminase deficiency in several fields, including Peripheral blood mononuclear cell, Asymptomatic, Adenine nucleotide and Immunodeficiency.
Within one scientific family, Michael S. Hershfield focuses on topics pertaining to Pharmacology under Adenine nucleotide, and may sometimes address concerns connected to Pegloticase and Hyperuricemia.
His research in Adenosine intersects with topics in Hydrolase and Adenosylhomocysteinase.
His most cited work include:
- Early-Onset Stroke and Vasculopathy Associated with Mutations in ADA2 (385 citations)
- Treatment of adenosine deaminase deficiency with polyethylene glycol-modified adenosine deaminase. (379 citations)
- Treatment of adenosine deaminase deficiency with polyethylene glycol-modified adenosine deaminase. (379 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Adenosine deaminase, Immunology, Adenosine deaminase deficiency, Biochemistry and Severe combined immunodeficiency.
Michael S. Hershfield interconnects Molecular biology, Genetic enhancement and Enzyme replacement therapy in the investigation of issues within Adenosine deaminase.
In most of his Immunology studies, his work intersects topics such as Hematopoietic stem cell transplantation.
The various areas that Michael S. Hershfield examines in his Adenosine deaminase deficiency study include Deoxyadenosine triphosphate, Antibody and Lymphocyte.
As part of his studies on Biochemistry, Michael S. Hershfield frequently links adjacent subjects like Pharmacology.
His Adenosine research includes themes of Hydrolase and Adenosylhomocysteinase.
He most often published in these fields:
- Adenosine deaminase (44.76%)
- Immunology (37.76%)
- Adenosine deaminase deficiency (29.37%)
What were the highlights of his more recent work (between 2015-2021)?
- Immunology (37.76%)
- Adenosine deaminase (44.76%)
- Hematopoietic stem cell transplantation (9.44%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include Immunology, Adenosine deaminase, Hematopoietic stem cell transplantation, Adenosine deaminase deficiency and Internal medicine.
His Immunology research is multidisciplinary, incorporating perspectives in Genotype, Disease and Polyarteritis nodosa, Adenosine Deaminase 2 Deficiency.
Michael S. Hershfield combines subjects such as Enzyme replacement therapy, Heterozygote advantage, Compound heterozygosity, Primary immunodeficiency and Severe combined immunodeficiency with his study of Adenosine deaminase.
His Hematopoietic stem cell transplantation study combines topics in areas such as Missense mutation, Combined immunodeficiencies, Immune system, Newborn screening and Genetic enhancement.
The study incorporates disciplines such as Hypogammaglobulinemia, Transplantation and Cancer research in addition to Adenosine deaminase deficiency.
His Internal medicine research integrates issues from Gastroenterology and Immunodeficiency.
Between 2015 and 2021, his most popular works were:
- Pre-existing anti-polyethylene glycol antibody linked to first-exposure allergic reactions to pegnivacogin, a PEGylated RNA aptamer. (129 citations)
- Hematopoietic stem cell transplantation rescues the hematological, immunological, and vascular phenotype in DADA2 (65 citations)
- Deficiency of Adenosine Deaminase 2 Causes Antibody Deficiency. (57 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Enzyme
- Internal medicine
Michael S. Hershfield mainly investigates Immunology, Adenosine deaminase, Polyarteritis nodosa, Hematopoietic stem cell transplantation and Disease.
Particularly relevant to Immunodeficiency is his body of work in Immunology.
His Adenosine deaminase study combines topics from a wide range of disciplines, such as Heterozygote advantage, Young adult and Pure red cell aplasia.
His work deals with themes such as Genetic enhancement and Adenosine deaminase deficiency, which intersect with Hematopoietic stem cell transplantation.
His Adenosine deaminase deficiency research is within the category of Severe combined immunodeficiency.
His studies deal with areas such as Hyperuricemia, Gout and Rheumatology as well as Disease.
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