D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 72 Citations 22,616 307 World Ranking 1055 National Ranking 28

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Internal medicine

The scientist’s investigation covers issues in Genetic enhancement, Immunology, Hematopoietic stem cell transplantation, Haematopoiesis and Severe combined immunodeficiency. The concepts of his Genetic enhancement study are interwoven with issues in Hematopoietic stem cell, Viral vector and Transplantation. His research combines Cell biology and Immunology.

The various areas that Alessandro Aiuti examines in his Hematopoietic stem cell transplantation study include Metachromatic leukodystrophy and Arylsulfatase A. His studies deal with areas such as Progenitor cell, CD34, Wiskott–Aldrich syndrome and Transduction as well as Haematopoiesis. Alessandro Aiuti has researched Bone marrow in several fields, including Myeloid and Cancer research.

His most cited work include:

  • A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1) (1328 citations)
  • The Chemokine SDF-1 Is a Chemoattractant for Human CD34+ Hematopoietic Progenitor Cells and Provides a New Mechanism to Explain the Mobilization of CD34+ Progenitors to Peripheral Blood (1296 citations)
  • Correction of ADA-SCID by Stem Cell Gene Therapy Combined with Nonmyeloablative Conditioning (998 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Immunology, Genetic enhancement, Haematopoiesis, Stem cell and Progenitor cell. His research integrates issues of Hematopoietic stem cell transplantation and Wiskott–Aldrich syndrome in his study of Immunology. As part of the same scientific family, Alessandro Aiuti usually focuses on Hematopoietic stem cell transplantation, concentrating on Immunodeficiency and intersecting with Autoimmunity.

The study incorporates disciplines such as Cancer research, Viral vector, Hematopoietic stem cell, Severe combined immunodeficiency and Transplantation in addition to Genetic enhancement. His Severe combined immunodeficiency research is multidisciplinary, incorporating elements of Adenosine deaminase and Chronic granulomatous disease. His study on Progenitor cell also encompasses disciplines like

  • CD34 and related Stromal cell,
  • Molecular biology and related Gene.

He most often published in these fields:

  • Immunology (50.64%)
  • Genetic enhancement (39.10%)
  • Haematopoiesis (23.72%)

What were the highlights of his more recent work (between 2018-2021)?

  • Genetic enhancement (39.10%)
  • Immunology (50.64%)
  • Cancer research (12.50%)

In recent papers he was focusing on the following fields of study:

Alessandro Aiuti mainly focuses on Genetic enhancement, Immunology, Cancer research, Haematopoiesis and Progenitor cell. His Genetic enhancement study combines topics in areas such as Hematopoietic stem cell transplantation, Stem cell, Wiskott–Aldrich syndrome, Viral vector and Hematopoietic stem cell. His Hematopoietic stem cell transplantation study incorporates themes from Autoimmunity, Bone marrow, EBI3 and Tuberculosis.

His research in Bone marrow tackles topics such as CD34 which are related to areas like Stromal cell and Mesenchymal stem cell. His Immunology research includes elements of Phenotype, Follicular phase and Disease. The Haematopoiesis study combines topics in areas such as Genome editing, Concomitant and Metachromatic leukodystrophy.

Between 2018 and 2021, his most popular works were:

  • Autoantibodies against type I IFNs in patients with life-threatening COVID-19. (503 citations)
  • A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection. (72 citations)
  • Intrabone hematopoietic stem cell gene therapy for adult and pediatric patients affected by transfusion-dependent ß-thalassemia. (65 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Internal medicine

Alessandro Aiuti spends much of his time researching Immunology, Genetic enhancement, Transplantation, Stem cell and Internal medicine. His Immunology research includes themes of Disease and Rash. As part of his studies on Genetic enhancement, he often connects relevant subjects like Wiskott–Aldrich syndrome.

His Transplantation study combines topics from a wide range of disciplines, such as Progenitor cell and Haematopoiesis, Hematopoietic stem cell. Alessandro Aiuti studied Hematopoietic stem cell and Bone marrow that intersect with Autoimmunity. His Internal medicine research is multidisciplinary, incorporating perspectives in Severe combined immunodeficiency, Oncology and Gene mutation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The Chemokine SDF-1 Is a Chemoattractant for Human CD34+ Hematopoietic Progenitor Cells and Provides a New Mechanism to Explain the Mobilization of CD34+ Progenitors to Peripheral Blood

A. Aiuti;I.J. Webb;C. Bleul;T. Springer.
Journal of Experimental Medicine (1997)

2080 Citations

A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)

Conrad C. Bleul;Robert C. Fuhlbrigge;Jose M. Casasnovas;Alessandro Aiuti.
Journal of Experimental Medicine (1996)

1863 Citations

Autoantibodies against type I IFNs in patients with life-threatening COVID-19.

Paul Bastard;Paul Bastard;Paul Bastard;Lindsey B. Rosen;Qian Zhang;Eleftherios Michailidis.
Science (2020)

1550 Citations

Correction of ADA-SCID by Stem Cell Gene Therapy Combined with Nonmyeloablative Conditioning

Alessandro Aiuti;Shimon Slavin;Memet Aker;Francesca Ficara.
Science (2002)

1378 Citations

Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy.

Alessandra Biffi;Eugenio Montini;Laura Lorioli;Martina Cesani.
Science (2013)

1201 Citations

Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome

Alessandro Aiuti;Luca Biasco;Samantha Scaramuzza;Francesca Ferrua.
Science (2013)

1088 Citations

Gene Therapy for Immunodeficiency Due to Adenosine Deaminase Deficiency

Alessandro Aiuti;Federica Cattaneo;Stefania Galimberti;Ulrike Benninghoff.
The New England Journal of Medicine (2009)

1060 Citations

Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial

Maria Sessa;Laura Lorioli;Francesca Fumagalli;Serena Acquati.
The Lancet (2016)

384 Citations

Hot spots of retroviral integration in human CD34+ hematopoietic cells

Claudia Cattoglio;Giulia Facchini;Daniela Sartori;Antonella Antonelli.
Blood (2007)

322 Citations

Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy

Alessandro Aiuti;Barbara Cassani;Grazia Andolfi;Massimiliano Mirolo.
Journal of Clinical Investigation (2007)

304 Citations

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