The scientist’s investigation covers issues in Genetic enhancement, Immunology, Hematopoietic stem cell transplantation, Haematopoiesis and Severe combined immunodeficiency. The concepts of his Genetic enhancement study are interwoven with issues in Hematopoietic stem cell, Viral vector and Transplantation. His research combines Cell biology and Immunology.
The various areas that Alessandro Aiuti examines in his Hematopoietic stem cell transplantation study include Metachromatic leukodystrophy and Arylsulfatase A. His studies deal with areas such as Progenitor cell, CD34, Wiskott–Aldrich syndrome and Transduction as well as Haematopoiesis. Alessandro Aiuti has researched Bone marrow in several fields, including Myeloid and Cancer research.
His main research concerns Immunology, Genetic enhancement, Haematopoiesis, Stem cell and Progenitor cell. His research integrates issues of Hematopoietic stem cell transplantation and Wiskott–Aldrich syndrome in his study of Immunology. As part of the same scientific family, Alessandro Aiuti usually focuses on Hematopoietic stem cell transplantation, concentrating on Immunodeficiency and intersecting with Autoimmunity.
The study incorporates disciplines such as Cancer research, Viral vector, Hematopoietic stem cell, Severe combined immunodeficiency and Transplantation in addition to Genetic enhancement. His Severe combined immunodeficiency research is multidisciplinary, incorporating elements of Adenosine deaminase and Chronic granulomatous disease. His study on Progenitor cell also encompasses disciplines like
Alessandro Aiuti mainly focuses on Genetic enhancement, Immunology, Cancer research, Haematopoiesis and Progenitor cell. His Genetic enhancement study combines topics in areas such as Hematopoietic stem cell transplantation, Stem cell, Wiskott–Aldrich syndrome, Viral vector and Hematopoietic stem cell. His Hematopoietic stem cell transplantation study incorporates themes from Autoimmunity, Bone marrow, EBI3 and Tuberculosis.
His research in Bone marrow tackles topics such as CD34 which are related to areas like Stromal cell and Mesenchymal stem cell. His Immunology research includes elements of Phenotype, Follicular phase and Disease. The Haematopoiesis study combines topics in areas such as Genome editing, Concomitant and Metachromatic leukodystrophy.
Alessandro Aiuti spends much of his time researching Immunology, Genetic enhancement, Transplantation, Stem cell and Internal medicine. His Immunology research includes themes of Disease and Rash. As part of his studies on Genetic enhancement, he often connects relevant subjects like Wiskott–Aldrich syndrome.
His Transplantation study combines topics from a wide range of disciplines, such as Progenitor cell and Haematopoiesis, Hematopoietic stem cell. Alessandro Aiuti studied Hematopoietic stem cell and Bone marrow that intersect with Autoimmunity. His Internal medicine research is multidisciplinary, incorporating perspectives in Severe combined immunodeficiency, Oncology and Gene mutation.
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The Chemokine SDF-1 Is a Chemoattractant for Human CD34+ Hematopoietic Progenitor Cells and Provides a New Mechanism to Explain the Mobilization of CD34+ Progenitors to Peripheral Blood
A. Aiuti;I.J. Webb;C. Bleul;T. Springer.
Journal of Experimental Medicine (1997)
A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)
Conrad C. Bleul;Robert C. Fuhlbrigge;Jose M. Casasnovas;Alessandro Aiuti.
Journal of Experimental Medicine (1996)
Autoantibodies against type I IFNs in patients with life-threatening COVID-19.
Paul Bastard;Paul Bastard;Paul Bastard;Lindsey B. Rosen;Qian Zhang;Eleftherios Michailidis.
Science (2020)
Correction of ADA-SCID by Stem Cell Gene Therapy Combined with Nonmyeloablative Conditioning
Alessandro Aiuti;Shimon Slavin;Memet Aker;Francesca Ficara.
Science (2002)
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy.
Alessandra Biffi;Eugenio Montini;Laura Lorioli;Martina Cesani.
Science (2013)
Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome
Alessandro Aiuti;Luca Biasco;Samantha Scaramuzza;Francesca Ferrua.
Science (2013)
Gene Therapy for Immunodeficiency Due to Adenosine Deaminase Deficiency
Alessandro Aiuti;Federica Cattaneo;Stefania Galimberti;Ulrike Benninghoff.
The New England Journal of Medicine (2009)
Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial
Maria Sessa;Laura Lorioli;Francesca Fumagalli;Serena Acquati.
The Lancet (2016)
Hot spots of retroviral integration in human CD34+ hematopoietic cells
Claudia Cattoglio;Giulia Facchini;Daniela Sartori;Antonella Antonelli.
Blood (2007)
Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy
Alessandro Aiuti;Barbara Cassani;Grazia Andolfi;Massimiliano Mirolo.
Journal of Clinical Investigation (2007)
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