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Molecular Biology
Italy
2023

D-Index & Metrics

Molecular Biology

D-Index
79
Citations
27059
World Ranking
1032
National Ranking
16

Research.com Recognitions

  • 2023 - Research.com Molecular Biology in Italy Leader Award

Overview

Fulvio Mavilio is affiliated with the University of Modena and Reggio Emilia in Italy. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with significant contributions also to Medicine. Within these broader areas, their work focuses on key subfields such as Genetics, Molecular Biology, Immunology, Physiology, and Hematology.

The topics explored in their publications cover a range of biomedical research areas, including:

  • Hemoglobinopathies and Related Disorders
  • CRISPR and Genetic Engineering
  • Virus-based gene therapy research
  • Lysosomal Storage Disorders Research
  • Muscle Physiology and Disorders
  • Neurogenetic and Muscular Disorders Research
  • Iron Metabolism and Disorders

Fulvio Mavilio has contributed to several recent papers, highlighting advancements in gene therapy and genetic editing technologies. Notable works include:

  • "Editing a γ-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype," published in 2020 in Science Advances
  • "Safety and efficacy of gene replacement therapy for X-linked myotubular myopathy (ASPIRO): a multinational, open-label, dose-escalation trial," published in 2023 in The Lancet Neurology
  • "Designing Lentiviral Vectors for Gene Therapy of Genetic Diseases," published in 2021 in Viruses
  • "Correction of β-thalassemia by CRISPR/Cas9 editing of the α-globin locus in human hematopoietic stem cells," published in 2021 in Blood Advances
  • "Muscle-directed gene therapy corrects Pompe disease and uncovers species-specific GAA immunogenicity," published in 2021 in EMBO Molecular Medicine

These publications have appeared in a variety of scientific venues. Among the frequent journals in which this researcher publishes are:

  • Blood
  • Gastroenterology
  • Molecular Genetics and Metabolism
  • Neuromuscular Disorders
  • Science Advances

Collaboration is evident in their work with several frequent co-authors, including:

  • Anne Chalumeau
  • Annarita Miccio
  • Marina Cavazzana
  • Mario Amendola
  • Michael W. Lawlor

Best Publications

  • Muscle Regeneration by Bone Marrow-Derived Myogenic Progenitors

    Giuliana Ferrari;Gabriella Cusella;Gabriella Cusella;De Angelis;De Angelis;Marcello Coletta;Marcello Coletta

  • HSV-TK Gene Transfer into Donor Lymphocytes for Control of Allogeneic Graft-Versus-Leukemia

    Chiara Bonini;Giuliana Ferrari;Simona Verzeletti;Paolo Servida

  • Gene therapy in peripheral blood lymphocytes and bone marrow for ADA- immunodeficient patients

    Claudio Bordignon;Luigi D. Notarangelo;Nadia Nobili;Giuliana Ferrari

  • Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells

    Fulvio Mavilio;Graziella Pellegrini;Stefano Ferrari;Francesca Di Nunzio

  • IL-7 and IL-15 instruct the generation of human memory stem T cells from naïve precursors

    Nicoletta Cieri;Barbara Camisa;Fabienne Cocchiarella;Mattia Forcato

  • Sequential activation of HOX2 homeobox genes by retinoic acid in human embryonal carcinoma cells

    Antonio Simeone;Dario Acampora;Laura Arcioni;Peter W. Andrews

  • Muscle-derived hematopoietic stem cells are hematopoietic in origin

    Shannon L. McKinney-Freeman;Kathyjo A. Jackson;Fernando D. Camargo;Giuliana Ferrari

  • Outcomes Following Gene Therapy in Patients With Severe Wiskott-Aldrich Syndrome

    Salima Hacein-Bey Abina;H. Bobby Gaspar;Johanna Blondeau;Laure Caccavelli

  • Cytokine-dependent granulocytic differentiation. Regulation of proliferative and differentiative responses in a murine progenitor cell line.

    M. Valtieri;D. J. Tweardy;D. Caracciolo;Keith R Johnson

  • Granulocyte colony-stimulating factor gene transfer suppresses tumorigenicity of a murine adenocarcinoma in vivo.

    M P Colombo;G Ferrari;A Stoppacciaro;M Parenza

  • Human embryonic hemopoiesis. Kinetics of progenitors and precursors underlying the yolk sac----liver transition.

    G Migliaccio;A R Migliaccio;S Petti;F Mavilio

  • The future of gene therapy

    Marina Cavazzana-Calvo;Adrian Thrasher;Fulvio Mavilio

  • Nuclear architecture dictates HIV-1 integration site selection

    Bruna Marini;Attila Kertesz-Farkas;Hashim Ali;Bojana Lucic;Bojana Lucic

  • Hot spots of retroviral integration in human CD34+ hematopoietic cells

    Claudia Cattoglio;Giulia Facchini;Daniela Sartori;Antonella Antonelli

  • Growth factor requirements of childhood acute leukemia: establishment of GM-CSF-dependent cell lines

    B Lange;M Valtieri;D Santoli;D Caracciolo

  • Differential regulation by retinoic acid of the homeobox genes of the four HOX loci in human embryonal carcinoma cells

    Antonio Simeone;Dario Acampora;Vincenzo Nigro;Antonio Faiella

  • The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity.

    Jens Berthelsen;Vincenzo Zappavigna;Elisabetta Ferretti;Fulvio Mavilio

  • Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy

    Alessandro Aiuti;Barbara Cassani;Grazia Andolfi;Massimiliano Mirolo

  • HOX gene activation by retinoic acid

    Edoardo Boncinelli;Antonio Simeone;Dario Acampora;Fulvio Mavilio

  • HMG1 interacts with HOX proteins and enhances their DNA binding and transcriptional activation

    V. Zappavigna;L. Falciola;M. Helmer-Citterich;F. Mavilio

Frequent Co-Authors

Giuliana Ferrari
Giuliana Ferrari Vita-Salute San Raffaele University
Adrian J. Thrasher
Adrian J. Thrasher University College London
Chiara Bonini
Chiara Bonini Vita-Salute San Raffaele University
Claudio Bordignon
Claudio Bordignon MolMed (Italy)
Michele De Luca
Michele De Luca University of Modena and Reggio Emilia
Edoardo Boncinelli
Edoardo Boncinelli Vita-Salute San Raffaele University
Alessandro Aiuti
Alessandro Aiuti Vita-Salute San Raffaele University
Antonio Simeone
Antonio Simeone King's College London
Philippe Moullier
Philippe Moullier University of Nantes
Gianluca De Bellis
Gianluca De Bellis National Academies of Sciences, Engineering, and Medicine

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