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Biology and Biochemistry

D-Index
52
Citations
14881
World Ranking
16476
National Ranking
523

Overview

Michele De Luca is affiliated with the University of Modena and Reggio Emilia in Italy. They have contributed extensively to the field of Biochemistry, Genetics and Molecular Biology, with a particular focus on Molecular Biology, Cell Biology, and Genetics. Their research interests also touch on Plant Science and Biomaterials.

The scientist's work spans several main topics including:

  • Skin and Cellular Biology Research
  • Pluripotent Stem Cells Research
  • Melanin and Skin Pigmentation
  • RNA Interference and Gene Delivery
  • Silk-based Biomaterials and Applications
  • Transgenic Plants and Applications
  • Plant Reproductive Biology

Michele De Luca has published in a variety of scientific journals. Frequent publication venues include:

  • Frontiers in Genetics
  • Frontiers in Public Health
  • Nature Communications
  • New England Journal of Medicine
  • EMBO Reports

Recent papers authored or co-authored by De Luca and colleagues include:

  • Single-keratinocyte transcriptomic analyses identify different clonal types and proliferative potential mediated by FOXM1 in human epidermal stem cells (2021, Nature Communications)
  • Transgenic Epidermal Cultures for Junctional Epidermolysis Bullosa - 5-Year Outcomes (2021, New England Journal of Medicine)
  • Cost and availability of novel cell and gene therapies (2023, EMBO Reports)
  • Hologene 5: A Phase II/III Clinical Trial of Combined Cell and Gene Therapy of Junctional Epidermolysis Bullosa (2021, Frontiers in Genetics)
  • Epigenetic and metabolic regulation of epidermal homeostasis (2021, Experimental Dermatology)

The scientist collaborates frequently with several co-authors, including:

  • Laura De Rosa
  • Elena Enzo
  • Laura Sercia
  • Mattia Forcato
  • Maria Pia Polito

Best Publications

  • p63 identifies keratinocyte stem cells

    Graziella Pellegrini;Elena Dellambra;Osvaldo Golisano;Enrica Martinelli

  • Long-term restoration of damaged corneal surfaces with autologous cultivated corneal epithelium

    Graziella Pellegrini;Carlo E Traverso;Adriano Tito Franzi;Mario Zingirian

  • Limbal stem-cell therapy and long-term corneal regeneration

    Paolo Rama;Stanislav Matuska;Giorgio Paganoni;Alessandra Spinelli

  • Location and Clonal Analysis of Stem Cells and Their Differentiated Progeny in the Human Ocular Surface

    Graziella Pellegrini;Osvaldo Golisano;Patrizia Paterna;Alessandro Lambiase

  • Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells

    Fulvio Mavilio;Graziella Pellegrini;Stefano Ferrari;Francesca Di Nunzio

  • Regeneration of the entire human epidermis using transgenic stem cells

    Tobias Hirsch;Tobias Rothoeft;Norbert Teig;Johann W. Bauer

  • Autologous fibrin-cultured limbal stem cells permanently restore the corneal surface of patients with total limbal stem cell deficiency.

    Paolo Rama;Stefano Bonini;Alessandro Lambiase;Osvaldo Golisano

  • Isoforms of ΔNp63 and the migration of ocular limbal cells in human corneal regeneration

    Enzo Di Iorio;Vanessa Barbaro;Alessandro Ruzza;Diego Ponzin

  • A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status.

    James G. Rheinwald;William C. Hahn;William C. Hahn;Matthew R. Ramsey;Jenny Y. Wu

  • New ISSCR Guidelines Underscore Major Principles for Responsible Translational Stem Cell Research

    Insoo Hyun;Olle Lindvall;Lars Ährlund-Richter;Elena Cattaneo

  • Downregulation of 14-3-3σ Prevents Clonal Evolution and Leads to Immortalization of Primary Human Keratinocytes

    Elena Dellambra;Osvaldo Golisano;Sergio Bondanza;Emanuela Siviero

  • Regeneration of squamous epithelia from stem cells of cultured grafts.

    Michele De Luca;Graziella Pellegrini;Howard Green

  • Advances in stem cell research and therapeutic development

    Michele De Luca;Alessandro Aiuti;Giulio Cossu;Malin Parmar

  • C/EBPδ regulates cell cycle and self-renewal of human limbal stem cells

    Vanessa Barbaro;Anna Testa;Enzo Di Iorio;Fulvio Mavilio

  • In vitro paracrine regulation of human keratinocyte growth by fibroblast-derived insulin-like growth factors.

    Antonina Barreca;Michele de Luca;Patrizia Del Monte;Sergio Bondanza

  • Evidence that human oral epithelium reconstituted in vitro and transplanted onto patients with defects in the oral mucosa retains properties of the original donor site.

    Michele De Luca;Enrico Albanese;Mauro Megna;Ranier I. Cancedda

  • Marketing of unproven stem cell–based interventions: A call to action

    Douglas Sipp;Timothy Caulfield;Jane Kaye;Jan Barfoot

  • Corrective transduction of human epidermal stem cells in laminin-5-dependent junctional epidermolysis bullosa.

    Elena Dellambra;Joëlle Vailly;Graziella Pellegrini;Sergio Bondanza

  • Treatment of "Stable" Vitiligo by Timedsurgery and Transplantation of Cultured Epidermal Autografts

    Liliana Guerra;Sergio Capurro;Francesco Melchi;Grazia Primavera

  • The control of epidermal stem cells (holoclones) in the treatment of massive full-thickness burns with autologous keratinocytes cultured on fibrin. [5YIF: 3.60, Citations: 215]

    Graziella Pellegrini;R. Ranno;G. Stracuzzi;S. Bondanza

Frequent Co-Authors

Ranieri Cancedda
Ranieri Cancedda University of Genoa
Fulvio Mavilio
Fulvio Mavilio University of Modena and Reggio Emilia
Leonard D. Kohn
Leonard D. Kohn National Institutes of Health
Giovanna Zambruno
Giovanna Zambruno Bambino Gesù Children's Hospital
Stefano Ferrari
Stefano Ferrari Veneto Eye Bank Foundation
Pier Carlo Marchisio
Pier Carlo Marchisio Vita-Salute San Raffaele University
Pilar Santisteban
Pilar Santisteban Spanish National Research Council
Giuliana Ferrari
Giuliana Ferrari Vita-Salute San Raffaele University
Elena Cattaneo
Elena Cattaneo University of Milan
Andrea Ballabio
Andrea Ballabio Baylor College of Medicine

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